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ISOLATED UNILATERAL PTOSIS DUE TO JUVENILE OCULAR MYASTHENIA GRAVIS, CASE REPORT Pramanto, Adji; Sutyawan, Eka
Majalah Oftalmologi Indonesia Vol 51 No 1 (2025): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v51i1.101693

Abstract

Introduction: Ocular myasthenia gravis in children is an uncommon autoimmune condition impacting the neuromuscular junction. Typical manifestations include weakness in the levator palpebrae, orbicularis oculi, or extraocular muscles, leading to symptoms such as ptosis and binocular diplopia.   Case Report: a 5-year-old girl was brought in with the primary concern of her right eyelid drooping for the last 11 days. The weakness of the eyelid is more pronounced during daytime and nighttime but improves upon waking up in the morning. The patient did not experience difficulties in speaking, swallowing, or breathing. There was no extremity weakness. Ophthalmologic examination reveals orthophoric eye position without restriction of eye movement. The patient exhibited drooping of the right eyelid. Repetitive Nerve Stimulation (RNS) confirmed the presence of a lesion at the neuromuscular junction. Consequently, the diagnosis was made of myasthenia gravis causing the right eye ptosis. Seven months after beginning treatment with oral pyridostigmine, there was a noticeable improvement in the patient's condition during a follow-up examination.   Discussion: Juvenile ocular myasthenia gravis, can present with isolated unilateral ptosis. Diagnosis of mechanical/congenital ptosis, external ophthalmoplegia, and Horner syndrome has ptosis as a manifestation was ruled out.   Conclusion: The diagnosis and initial management of juvenile ocular myasthenia gravis play a crucial role in preventing disease progression. First-line therapy with oral pyridostigmine is safe and effective. The prognosis for ocular myasthenia gravis in prepubertal patients is generally favorable.
AGE AND OCULAR MANIFESTATIONS IN HIV PATIENTS AT VCT POLYCLINIC, PROF. DR. IGNG NGOERAH HOSPITAL, DENPASAR PERIOD JUNE 2020 TO APRIL 2023: A HOSPITAL BASED ANALYTIC RETROSPECTIVE STUDY Pramanto, Adji; Juliari, I Gusti Ayu Made; Pramita, Ida Ayu Ary
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.29600

Abstract

Ocular manifestation in HIV refers to a wide range of eye problems. The likelihood of experiencing at least one visual symptom increases with age in HIV patients. The possible explanation is that older people may be more susceptible to other health problems that can exacerbate ocular manifestations. People who have had HIV for a longer period also may experience decline in the immune function, and accumulation of chronic inflammation and damage over time therefore increasing their risk of complications. Examining the possible clinical correlation between age and ocular manifestation in HIV patients was the primary objective of the research. 159 HIV-positive Patients at Prof. IGNG. Ngoerah Central General Hospital Voluntary Counseling and Testing (VCT) Clinic in Denpasar, Bali were examined for ocular-related complaints between June 2020 and April 2023 as part of this hospital-based analytic retrospective study. The research found no statistically significant correlation between age and the occurrence of ocular symptoms (p = 0.276). However, the percentage of HIV patients that have ocular manifestations increase along with older age group. Age and ocular manifestation did not correlate significantly in the HIV patient population. To further understand the relationship between age, length of HIV infection, and the onset of ocular symptoms, further research is required.