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Optimizing Burn Injury Care: A Comparative Network Meta-Analysis of Skin Grafts' Efficacy Del Rosario Puling, Imke Maria; Pramana Giri, Nyoman Deva; Almadita, Teresa; Limantara, Jane; Arviansyah, Arviansyah
Jurnal Kedokteran Brawijaya Vol. 33 No. 3 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.03.8

Abstract

Burn injuries, causing approximately 180,000 deaths. Skin grafting serves as a cornerstone intervention in burn injury management. This study aimed to evaluate the efficacy of different types of skin grafts in promoting the healing process of burn injuries. The outcomes of the study were the reepithelialization time and repigmentation rate of skin graft. Quality appraisal was done using ROBINS-I and the Newcastle Ottawa Scale, while network and single arm meta-analysis were conducted using R-Studio. A literature search across 6 databases resulted in the selection of 7 articles. Quality assessment categorized 6 studies as low- and 1 as moderate-risk of bias studies. The device facilitated autologous skin cell increase in reepithelialization rate (OR=5.21; 95% CI=0.24-114.41), followed by autologous skin cell and synthetic graft (OR=0.47; 95% CI=0.04-5.98), topical agent (OR=0.30; 95% CI=0.06-1.47), and Xenograft (OR=0.09; 95% CI=0.00-4.89). Furthermore, the single-arm meta-analysis showed an overall repigmentation rate of 61.49%, with xenograft displaying the highest repigmentation rate (87.50%), followed by synthetic graft (70.32%), and autologous skin cell (37.54%). Xenografts have proven effective in promoting burn wound healing. Nevertheless, the outstanding efficacy and minimal repigmentation of device-facilitated autologous skin cell transplantation highlight its potential in clinical practice.
Optimizing Burn Injury Care: A Comparative Network Meta-Analysis of Skin Grafts' Efficacy Del Rosario Puling, Imke Maria; Pramana Giri, Nyoman Deva; Almadita, Teresa; Limantara, Jane; Arviansyah, Arviansyah
Jurnal Kedokteran Brawijaya Vol. 33 No. 3 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.03.8

Abstract

Burn injuries, causing approximately 180,000 deaths. Skin grafting serves as a cornerstone intervention in burn injury management. This study aimed to evaluate the efficacy of different types of skin grafts in promoting the healing process of burn injuries. The outcomes of the study were the reepithelialization time and repigmentation rate of skin graft. Quality appraisal was done using ROBINS-I and the Newcastle Ottawa Scale, while network and single arm meta-analysis were conducted using R-Studio. A literature search across 6 databases resulted in the selection of 7 articles. Quality assessment categorized 6 studies as low- and 1 as moderate-risk of bias studies. The device facilitated autologous skin cell increase in reepithelialization rate (OR=5.21; 95% CI=0.24-114.41), followed by autologous skin cell and synthetic graft (OR=0.47; 95% CI=0.04-5.98), topical agent (OR=0.30; 95% CI=0.06-1.47), and Xenograft (OR=0.09; 95% CI=0.00-4.89). Furthermore, the single-arm meta-analysis showed an overall repigmentation rate of 61.49%, with xenograft displaying the highest repigmentation rate (87.50%), followed by synthetic graft (70.32%), and autologous skin cell (37.54%). Xenografts have proven effective in promoting burn wound healing. Nevertheless, the outstanding efficacy and minimal repigmentation of device-facilitated autologous skin cell transplantation highlight its potential in clinical practice.
SEXUALLY HARMFUL BEHAVIOR IN AN ADOLESCENT WITH A REPORTED HISTORY OF CHILDHOOD SEXUAL VICTIMIZATION: A CASE REPORT Limantara, Jane
Journal of Psychiatry Psychology and Behavioral Research Vol. 7 No. 2 (2026): Emerging Perspectives in Mental Health: From Clinical Challenges to Innovative
Publisher : Departemen Psikiatri Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Sexually harmful behavior in adolescents presents developmental, diagnostic, forensic, and safeguarding challenges. A history of childhood sexual victimization may be clinically relevant, but it does not establish the cause of later harmful behavior. Methods: This case report describes a brief psychiatric evaluation conducted to support therapeutic follow-up for a 15-year-old male residing in a juvenile correctional facility. Information was obtained through autoanamnesis and a mental status examination. A structured assessment of the risk of repeated sexual violence was not conducted because a separate legal assessment was still pending Results: The patient reported a sexual offense against a 3-year-old child when he was 12, persistent intrusive urges associated with the prior behavior, anger and retaliatory thoughts preceding the offense, and repeated childhood sexual victimization by an older cousin. He denied sexual attraction to the child and attributed the offense to anger and retaliation. During the interview, he was calm and cooperative, with intact orientation, memory, and reality testing; insight was partial, and he described impaired judgment. The available information did not independently corroborate the reported history. Discuss: The available information is insufficient to establish conduct disorder or a paraphilic disorder. The reported urges require further assessment before they can be classified as obsessions, sexual fantasies, aggressive impulses, or another experience. The reported trauma history warrants sensitive clinical consideration but cannot be assumed to explain the offense. The absence of a structured risk assessment limits conclusions about recurrence risk. Conclusion: This case highlights developmentally informed diagnostic reasoning, cautious interpretation of trauma history, and the distinction between brief therapeutic follow-up and a comprehensive forensic or legal assessment. Ethical safeguards and protection of the identities of both the adolescent and the child victim are essential.