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Muzakkir Baits
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PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL DAUN TANAMAN JONGI (Dillenia serrata) MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Savitri Ananda; Mamat Pratama; Muzakkir Baits
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 3 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Jongi leaves (Dillernia serrata) is a type of medicinal plant which is used as an anti-inflammatory, antioxidant, antimicrobial, antitumor, anti-ulcer, immunoprevention, cancer chemoprevention, medicine for thrush, vomiting blood, fever, and wound medicine because it contains polyphenolic compounds, such as tannins and flavonoids. This study aims to determine the total flavonoid content of jongi leaves (Dillenia serrata) using the UV-VIS spectrophotometry method. This type of research is laboratory experimental using a spectrophotometer method based on the determination of extract levels and quarcetin standards. The stages of this research began with sample preparation, qualitative testing of flavonoid compounds, and ended with the determination of total flavonoid content of the sample and quarcetin standard. This study obtained results that positive jongi leaf extract contained flavonoids based on the results of identification using FeCl3 reagents and on the results of quantitative testing using UV-VIS spectrophotometry jongi fruit extract had a percentage of flavonoid content of 16.8633%.
Studi Literatur Penetapan Kadar Fenolik Ekstrak Etanol Daun Turi (Sesbania grandiflora L) secara Spektrofotometri UV-';Vis nurul aenung; Muzakkir Baits; Andi Trihadi
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Turi plant (Sesbania grandiflora L) is a fabaceae plant that is widely used by the local community as a medicine for sprains, wounds and bruises.Turi plants contain active compounds of alkaloids, flavonoids, saponins, triterpenoids, phenolics and tannins. The purpose of this study was to determine how much phenolic content contained in the ethanol extract of Turi leaves using UV-Vis Spectrophotometry . The research method used is the Literature Review method by collecting journals conducted online using Google and Google Scholar data bases, then selected 5 journals in accordance with the criteria in the study of literature. Based on the results of research from 5 journals it can be concluded that the ethanol extract of turi leaves has different levels in a row, namely 3,7± 0,44 mg/g, 8,9 ± 1,35 mg, 1445,9 ± 49,33 µg, 88,56 ± 0,09 mg/g dan 0,137 mg.
Analisis Kadar Siklamat Pada Selai Yang Beredar Di Perumahan BTP Kota Makassar Dengan Metode Spektrofotometri UV-Vis Ayu Andini; Harti Widiastuti; Muzakkir Baits
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Sweeteners are chemical compounds that are widely added and used in various processed food and beverage products, one of which is jam. Jam is a semi-solid food made from fruit or other processed products. Sweeteners consist of natural sweeteners and artificial sweeteners. Cyclamate is one of the artificial sweeteners that is often used in society because it has a sweetness intensity 30 times that of pure sugar. Excessive use of cyclamate can cause negative effects on health such as cancer (carcinogenic), nerve disorders, impaired liver function, stomach irritation and changes in cell function. The maximum limit for using cyclamate in jam according to SNI 01-0222-1995 is 2 g/kg. This study aims to identify and determine the levels of cyclamate in jam circulating in BTP Makassar housing. The type of research used is laboratory observation with simple random sampling technique. This research was conducted qualitatively (TLC and precipitation method) and quantitatively (uv-vis spectrophotometric method). The results of this study indicated that all negative samples contained cyclamate with a standard Rf value of 0.875 for cyclamate.
Analisis Kadar Flavonoid Ekstrak Etanol Cabe Rawit, Cabe Keriting, Dan Cabe Besar Menggunakan Metode Spektrofotometri UV-VIS Nur Fadillah; Muzakkir Baits; St Maryam
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Chili fruit is a type of medicinal plant which is used as an anti-inflammatory, analgesic, antiflatulant, headache and rheumatism because it contains capsaicin, capsantin, carotenoids, essential alkaloids, resin, volatile oil, multivitamins. This study aims to determine the total flavonoid content of three types of chili using the UV-VIS spectrophotometry method. This type of research is laboratory experimental using a spectrophotometer method based on the determination of extract levels and quarcetin standards. The stages of this study began with sample preparation, extraction of compounds in the sample using ethanol solvent, and ended with the determination of total flavonoid content of the chili fruit sample and quarcetin standard. This study found that the average total flavonoid content for samples of bird's eye chilies, large chilies, and curly chilies was 19.695; 31.72; and 16.011 mg QE/g extract. The percentage of total flavonoid content in bird's eye chilies, large chilies, and curly chilies in this study were 1.9695%; 3.172%; and 1.6011%.
UJI AKTIVITAS ANTIOKSIDAN DARI TEH DAUN TANAMAN KAKAO (Theobroma cacao L.) BERDASARKAN TEMPAT TUMBUH DENGAN METODE PEREDAMAN RADIKAL BEBAS DPPH Nurizzah Aulia Syam; St. Maryam; Muzakkir Baits
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Tanaman kakao merupakan salah satu tanaman yang digunakan oleh masyarakat sebagai obat tradisional. Daun tanaman kakao mengandung metabolit sekunder yaitu flavonoid,saponin dan tanin serta mengandung senyawa fenolat, yang juga memiliki peran sebagai antioksidan. Tujuan dari penelitian ini untuk mengetahui aktivitas antioksidan dan menganalisa IC50 dari teh daun tanaman kakao (Theobroma cacao L.) dengan menggunakan metode DPPH (2,2-difenil-1-pikrilhidrazil). Sampel yang digunakan berasal dari tiga daerah yaitu Jeneponto, Wajo, dan Malino. Berdasarkan hasil penelitian, menunjukkan bahwa sediaan teh daun kakao (Theobroma cacao L.) memiliki aktivitas sebagai antioksidan. Nilai IC50 sediaan teh daun kakao (Theobroma cacao L.) Jeneponto sebesar 187,946 µg/mL, Wajo 309,629 µg/mL, dan Malino sebesar 314,055 µg/mL dengan kategori klasifikasi sangat lemah. Sediaan teh daerah Jeneponto memiliki aktivitas antioksidan yang lebih baik dari dua daerah lainnya. Kata kunci: Antioksidan, DPPH (2,2-difenil-1-pikrilhidrazil), Theobroma cacao L., Kuarsetin.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL AKAR BAJAKAH TAMPALA (Spatholobus Littoralis Hassk) MENGGUNAKAN METODE PEREDAMAN RADIKAL BEBAS DPPH Wina Astri Sari; Masdiana Tahir; Muzakkir Baits
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Bajakah tampala (Spatholobus littoralis Hassk.) is a plant that lives on vines in tropical areas. This plant comes from Sebuku Village, North Kalimantan. The Bajakah Tampala plant contains saponins, flavonoids and tannins. The roots of the Bajakah Tampala plant are thought to have strong antioxidant activity which is able to reduce the activity of free radicals. The aim of this research is to analyze the antioxidant activity of Bajakah Tampala roots using the DPPH reduction method using a UV Vis spectrophotometer which is based on calculating the IC50 value. The results of this study indicate that the ethanol extract of Bajakah Tampala roots has antioxidant activity against DPPH free radicals with an IC50 value of 9.206 µg/mL. which is included in the group of very strong antioxidants.
Antioxidant Activity ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT OF RED BAJAKAH KALALAWIT ROOTS (Uncaria gambir Roxb) USING THE FRAP METHOD Arru'nnisa Ika Nur Ilmi Aris; Muzakkir Baits; Asriani Suhaenah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 4 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Akar bajakah kalalawit merah (Uncaria gambir Roxb) merupakan salah satu tanaman yang dikenal memiliki kandungan alkaloid, fenol, dan triterpenoid yang digunakan untuk mengobati kanker, tumor, luka, penuaan dini, diabetes, dan antioksidan. Antioksidan adalah suatu senyawa yang memiliki struktur molekul yang dapat memberikan elektron untuk molekul radikal bebas yang tidak stabil tanpa terganggu sama sekali sehingga dapat memutuskan reaksi berantai radikal bebas. Tujuan penelitian ini adalah untuk mengetahui aktivitas antioksidan ekstrak etanol akar bajakah kalalawit merah (Uncaria gambir Roxb) menggunakan metode FRAP, berdasarkan kemampuan sampel mereduksi ion Fe3+ menjadi Fe2+. Hasil pengujian kualitatif menunjukkan bahwa akar bajakah kalalawit merah (Uncaria gambir Roxb) mengandung senyawa alkaloid, flavonoid, fenolik,dan tannin. Hasil pengujian kuantitatif diperoleh nilai rata-rata aktivitas antioksidan ekstrak etanol akar bajakah kalalawit merah (Uncaria gambir Roxb) yaitu sebesar 193,403 mg QE/g ekstrak.
Co-Authors Andi Trihadi Arru'nnisa Ika Nur Ilmi Aris Asriani Suhaenah Ayu Andini Harti Widiastuti Mamat Pratama Masdiana Tahir Mochammad Imron Awalludin NUR FADILLAH Nurizzah Aulia Syam nurul aenung Savitri Ananda Wina Astri Sari