Rezki Amriati Syarif
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Uji Toksisitas Ekstrak Kulit Buah Tanaman Jeruk Purut (Citrus hystrix DC.) Dengan Menggunakan Metode Brine Shrimp Lethality Test (BSLT) Isti Aprilyanie; Virsa Handayani; Rezki Amriati Syarif
Makassar Natural Product Journal (MNPJ) April 2023
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Kaffir lime peel extract (Citrus hystrix DC.) contains flavonoids and alkaloids still rarely used as medicine; however, its toxicity is lack of the research until now. The research aimed to determine the effects of toxicity in the extracts by Brine Shrimp Lethality test (BSLT). The extraction used maceration and infusion. The former used ethanol of 70% with the thick extract of 3.81 mg and the letter used aquadest with the dried extract of 2.77 mg. The screening-was conducted by observing the color change in the extract and obtained the toxicity effects at the concentration of 1 ppm, 3 ppm, 5 ppm, 7 ppm, and 9 ppm by obtaining LC50 values for both the ethanol extract of 0.98 ppm and water extract of 1.20 ppm. The results showed that the water and ethanol extracts of kaffir lime peel had toxic properties.
Total Flavonoid Content and Antioxidant Activity of Soursop Leaves from the Three Largest Producing Areas of South Sulawesi Province, Indonesia Faradiba, Faradiba; Amin, Asni; Sukmawati, Sukmawati; Achmad, Cindy Artikasari; Ananda, Ratu Hilda; Dicka Saputri; Nur adnin; Sinta Faradilla; Rezki Amriati Syarif
Window of Health : Jurnal Kesehatan Vol 7 No 4 (October 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.v7i4.1385

Abstract

Soursop leaves (Annona muricata L.) have anticancer and antioxidant activities; soursop leaves contain substances with the potential as antioxidants, such as flavonoids. Antioxidant assays and total flavonoid content from the three largest producing regions in South Sulawesi Province, namely Gowa, Takalar, and Pinrang, were carried out to obtain data on the antioxidant activity and flavonoid content of soursop leaves (Annona muricata L.) three areas. Total Flavonoid content was determined by UV-Vis spectrophotometry, and antioxidant activity was measured by the DPPH (1,1-Diphenyl-2-picryl Hydrazyl) method. According to the study, soursop leaves (Annona muricata L.) from the Gowa, Takalar, and Pinrang regions have total flavonoid levels of 7,6484 mg QE/g, 3,74429 mg QE/g, and 3,3105 mg QE/g, respectively, and IC50 values of 70.509 g/mL, 102.159 g/mL, and 99.246 g/mL, respectively. The results showed that soursop leaves (Annona muricata L.) from the Gowa area had the highest flavonoid content and antioxidant activity. Gowa region could be the best source of soursop leaves for developing soursop as an herbal remedy.