Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Andalas JSFK (Jurnal Sains Farmasi & Klinis)
Salsabila, Amilia
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Potensi Eugenol Fraksi Etil Asetat Bunga Cengkeh terhadap Proliferasi Kanker Serviks (HeLa Cell Line) Pratama, Fajri Rahendra; Sari, Annisa Permata; Susanti, Aprilia; Syakira, Hasya; Salsabila, Amilia; Arisanty, Dessy
Jurnal Kesehatan Andalas Vol. 13 No. 1 (2024): March 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i1.2326

Abstract

Cervix cancer, also known as cervical cancer, is a type of cancer that is caused mainly by oncogenic Human Papillomavirus (HPV), which attacks the cervix. One of the plants that can be used in medicine is clove. Objective: To analyzed the effect of a fraction of ethyl acetate eugenol of clove flower for the proliferation and migration of HeLa cells. Methods: This was an in vitro experiment. Ethyl acetate fraction was tested in vitro with the MTT Assay method. A scratch Assay is done to determine the migratory power of cancer cells to Trypan Blue to see (dead cells/living cells). Data collection techniques were carried out using experimental observation techniques. The data obtained in the MTT test is the percentage of inhibited HeLa cells. Scratch Assay results were analyzed with ImageJ software and the Trypan Blue method using the TC10 tool. Results: The MTT Assay test obtained an IC50 value of 24.51 µg/ml, the average migration of treatment cells 303 and the average control group 715 cells. The number of proliferating treatments 6.14 x 105 and control 12.1 x 105. Conclusion: Based on its potential, clove flower can be a candidate for cervical cancer cell therapy (HeLa Cell Line) in the future.Keywords:  anti-cervical cancer, cervical cancer, cell proliferation, MTT assay, scratch assay 
Formulation of Nanoemulsion Gel Cayenne Pepper (Capsicum frutescens) Extract as an Anti-inflammatory in Gout Arthritis Pain Salsabila, Amilia; Jonisa, Rahma Aprilya; Jannah, Yasmin Raudhatul; Yuningzia, Vannesha; Sari, Aulia Desvita; Lucida, Henny
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 2 (2025): J Sains Farm Klin 12(2), August 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.2.92-101.2025

Abstract

Cayenne pepper fruit extract has anti-inflammatory effects and could be a natural remedy of arthritis gout pain. The research aims to find the optimal formula for cayenne pepper extract nanoemulsion gel to improve its permeation capability and assess its effect on inflammation in mice induced by 1.5% carrageenan. Extraction using the maceration method followed by standardizing the extract. The optimal nanoemulsion formula is determined by constructing a pseudo-ternary diagram of the nanoemulsion base. The optimal formula obtained was 80% aquadest, 2% VCO, 18% SMIX (surfactant and cosurfactant). The cayenne pepper extract nanoemulsion is integrated with a gel base followed by evaluation. The extract nanoemulsion has been proven to form globules with a size of 54.4 nm, zeta potential of -23.6 mV, and polydispersity index of 0.403. Exudate volume and TNF-α levels were measured using the air pouch method to assess for anti-inflammatory activity. In comparison to other treatment groups, rats treated with chili pepper extract nanoemulsion gel had the lowest average exudate volume, with a statistically significant difference (DNMRT; P <0.05), according to the results of an ANOVA test combined with Duncan's post-hoc test. Meanwhile, the test for TNF-α levels did not show any significant differences
Co-Authors Annisa Permata Sari, Annisa Permata Aprilia Susanti, Aprilia Dessy Arisanty Henny Lucida Jannah, Yasmin Raudhatul Jonisa, Rahma Aprilya Pratama, Fajri Rahendra Sari, Aulia Desvita Syakira, Hasya Yuningzia, Vannesha