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All Journal Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh SENTRI: Jurnal Riset Ilmiah
Munandar, Rudi Haris
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Aerospace Engineering Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Pengaruh daun kelor dan dislipidemia terhadap kuantitas sperma Dahril; Muhammad Puteh Mauny; Munandar, Rudi Haris
Journal of Medical Science Vol 2 No 2 (2021): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.507 KB) | DOI: 10.55572/jms.v2i2.44

Abstract

Infertility is a global health problem affecting 1 of 10 couples in the world and its related to dyslipidemia. Dyslipidemia, as metabolic syndrome, had become global epidemic. It is estimated 12-37% Asian population and 12-26% of European population had dyslipidemia. Dyslipidemia decreased sperm count by increasing free radical oxygen species (ROS) caused of lypotoxicity and lipid peroxidation. Antioxidant is treatment choice for this problem. Drum stick (Moringa oleifera L) is medical herb that contain antioxidant compound such as alkaloid, flavonoid, tannin, vitamin C, E, and steroid. So, Moringa oleifera L leaf could protect sperm cells from free radicals of dyslipidemia and become alternative treatment for infertility. It was a post-test only control group design. Sample consist of 30 rats devided into 6 groups. It began with atherogenic diet to induce dyslipidemia. Then, Ethanol extract of Moringa oleifera L leaf was given. Sperm count was calculated microscopically with Neubauer chamber. Data analysis was using one way analysis of variance (ANNOVA) test, then continued with post hoc Duncan test. There were significant differences of total cholesterol, triglyceride, high density protein, low density protein, and sperm count between groups based on one way ANNOVA test (p < 0,05). On post hoc Duncan test, Dyslipidemia induction decreased sperm count compared to other groups. Ethanol extract of 200 mg/body weight and 400 mg/body weight leaf had no difference effect compared to atorvastatin. Ethanol extract of 800 mg/body weight leaf increased sperm count significantly compared to other groups.
Penanganan Bedah Tumor Mammae: Studi terhadap Efektivitas Teknik Onkoplastik dan Konservasi Payudara dalam Menurunkan Morbiditas Pasca Operasi Munandar, Rudi Haris
SENTRI: Jurnal Riset Ilmiah Vol. 5 No. 2 (2026): SENTRI : Jurnal Riset Ilmiah, Februari 2026 (In Press)
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v5i2.5681

Abstract

Breast cancer remains one of the most prevalent malignancies globally, prompting continuous refinement of surgical strategies to achieve optimal oncological control while preserving patients’ physical integrity and quality of life. The transition from radical mastectomy toward breast-conserving surgery and oncoplastic approaches reflects a paradigm shift that prioritizes both tumor eradication and postoperative functional–aesthetic outcomes. This study systematically evaluates the effectiveness of oncoplastic and breast-conserving techniques in reducing postoperative morbidity among patients with breast tumors. The research employed a Systematic Literature Review (SLR) guided by the PRISMA framework, focusing on peer-reviewed articles published within the past decade that addressed conservative surgical methods and reported morbidity-related outcomes. From 325 articles initially identified across multiple databases, 75 duplicates were removed, leaving 250 records for title and abstract screening. Subsequently, 125 articles underwent full-text review; 40 were excluded due to inaccessibility, and 55 did not meet the eligibility criteria. Ultimately, 30 studies fulfilled all inclusion requirements and were analyzed comprehensively. The findings indicate that oncoplastic surgery expands the eligibility criteria for breast-conserving procedures without elevating local recurrence rates, while simultaneously improving cosmetic satisfaction and overall quality of life. Conventional breast-conserving surgery combined with radiotherapy demonstrates long-term oncological safety comparable to mastectomy, with added advantages in maintaining body image and psychosocial well-being. Determinants of successful outcomes include anatomical suitability, tumor dimension and topography, surgical expertise, multidisciplinary collaboration, and institutional support systems. Collectively, the evidence underscores that integrative surgical approaches balancing oncological rigor and reconstructive precision contribute significantly to lowering postoperative morbidity.
Co-Authors Dahril Muhammad Puteh Mauny