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All Journal AcTion: Aceh Nutrition Journal Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh
Haroen, Elvia
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Hubungan Faktor Risiko Tuli Kongenital Pada Anak Dengan Hasil Pemeriksaan Fungsi Pendengaran di RSUDZA Haroen, Elvia; Alia, Dina; Osman, Gilbran Ayyubi; Khalilullah
Journal of Medical Science Vol 4 No 2 (2023): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v4i2.89

Abstract

Berdasarkan data Riset Kesehatan Dasar (Riskesdas) 2018, prevalensi penyakit jantung koroner sebagai etiologi utama sindrom koroner akut (SKA) di Indonesia sebesar 1,5%. Sekitar 5,4% pasien dengan penyakit arteri koroner (PAD) dan 0,9% pasien dengan SKA didiagnosis dengan trombositopenia. Menurut American Heart Association (AHA)/American College of Cardiology Foundation (ACCF) dan European Society of Cardiology (ESC), pemberian dual antiplatelet therapy (DAPT) yang terdiri dari aspirin dan antagonis reseptor P2Y12 adalah komponen mendasar dari manajemen SKA. Selain itu, terapi definitif berupa intervensi koroner perkutan (IKP), harus disertai dengan kombinasi obat antiplatelet dan antikoagulan untuk mencegah pembentukan trombus di lokasi intervensi koroner. Studi melaporkan bahwa trombositopenia yang diinduksi agen antiplatelet berkorelasi dengan mortalitas dan komorbiditas jangka pendek dan jangka panjang yang lebih tinggi pada pasien dengan SKA. Pada pasien dengan SKA dan trombositopenia, manajemen terapi pemberian antiplatelet masih sulit untuk dipertimbangkan dan saat ini tidak ada pedoman rekomendasi atau laporan konsensus untuk memandu dokter tentang manajemen pada kelompok ini. Oleh karena itu, kami berusaha untuk menjelaskan dari berbagai macam studi literatur tentang penggunaan DAPT pada pasien SKA dengan trombositopenia.
Beetroot (Beta vulgaris L.) juice supplementation and hemoglobin response in head and neck cancer patients after chemotherapy Andini, Dena Tria; Kurnia, Benny; Setiani, Lily; Ridwan, Azwar; Haroen, Elvia
AcTion: Aceh Nutrition Journal Vol 10, No 4 (2025): December
Publisher : Department of Nutrition at the Health Polytechnic of Aceh, Ministry of Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/action.v10i4.2701

Abstract

Anemia frequently occurs in patients with cancer and can worsen due to chemotherapy. The literature on non-pharmacological interventions to increase hemoglobin levels in patients with head and neck cancer following chemotherapy remains limited. This study aimed to measure the effect of beetroot juice supplementation on changes in hemoglobin levels in patients with head and neck cancer who had undergone chemotherapy. Methods: An experimental study with a one-group pretest–posttest design was conducted at dr. Zainoel Abidin General Hospital, Banda Aceh (July–November 2024). The sample consisted of all head and neck cancer patients undergoing chemotherapy cycles I–VI (total sampling, n=40), divided into two treatment groups: 100 g beetroot juice (n=20) and 200 g beetroot juice (n = 20). Hemoglobin levels were measured before and 14 days after the intervention. The analysis was performed using paired t-tests and effect sizes (Cohen’s d). Results: Administration of 100 g of beetroot juice did not significantly alter hemoglobin levels, with an average difference of −0.24 g/dL (p = 0.241). In contrast, the 200-gram dose resulted in a significant increase in hemoglobin levels, with an average difference of +0.44 g/dL (p = 0.016) after 14 days of intervention. Furthermore, the estimated Cohen’s d (pooled SD) was 0.51, indicating a moderate effect. In conclusion, the administration of 200 g beetroot juice for 14 days was associated with a small but statistically significant increase in hemoglobin levels in patients with head and neck cancer who underwent chemotherapy. Further studies in the form of RCTs with larger sample sizes and stricter compliance monitoring are needed to confirm these findings and assess their clinical relevance.
Co-Authors Alia, Dina Andini, Dena Tria Khalilullah Kurnia, Benny Osman, Gilbran Ayyubi Ridwan, Azwar Setiani, Lily