Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Sriwijaya Journal of Forensic and Medicolegal Sriwijaya Journal of Otorhinolaryngology
Rizki Ayu
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
The Influence of Traditional Indonesian Practices (Jamu) on the Prevention and Management of Common Otorhinolaryngology Complaints: A Mixed-Methods Study Fifia Ardinanti; Brian Edgar Wicaksana; Rizki Ayu; Mohammad Arfin; Abd El Nasser
Sriwijaya Journal of Otorhinolaryngology Vol. 2 No. 2 (2024): Sriwijaya Journal of Otorhinolaryngology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjorl.v3i1.189

Abstract

Introduction: In Indonesia, jamu (traditional herbal medicine) is culturally significant for health maintenance, including managing common ear, nose, and throat (ENT) complaints. This study explored the influence of jamu on the prevention and management of these complaints by examining patient beliefs, usage patterns, perceived outcomes, and associations with conventional healthcare-seeking. Methods: A mixed-methods sequential explanatory design was used. A cross-sectional survey of 1200 Indonesian adults assessed demographics, ENT complaint prevalence, jamu use (type, frequency, perceived effectiveness), and healthcare seeking. Subsequently, semi-structured interviews were conducted with 30 survey participants who regularly used jamu for ENT issues to explore their beliefs and experiences. Quantitative data were analyzed using descriptive statistics, chi-square tests, and logistic regression. Qualitative data underwent thematic analysis. Results: Survey data showed 68.5% experienced ENT complaints in the past year, with sore throat (42.3%), cough (38.7%), and nasal congestion (31.2%) most common. Among them, 53.2% used jamu, primarily turmeric-based for sore throat and ginger-based for cough and congestion. Regular jamu use was associated with perceived symptom relief (p < 0.001) but also with a higher likelihood of delaying conventional care for persistent symptoms (OR = 1.85). Interviews revealed strong cultural beliefs in jamu's efficacy and safety for mild ENT issues, often used as a first-line treatment due to its natural origin, fewer perceived side effects, and affordability. However, some acknowledged its limitations for severe conditions. Conclusion: Jamu plays a significant role in managing common ENT complaints in Indonesia, driven by strong cultural beliefs and perceived benefits. While users report symptom relief, delayed access to conventional care for serious conditions is a potential concern. Further research is needed to scientifically evaluate specific jamu formulations and develop integrated usage guidelines in Indonesia.
Toxicological Profiling of Unregulated Traditional Medicines in Unexplained Sudden Deaths Using LC-MS and Latent Class Analysis: A Forensic Autopsy-Based Study in South Sumatra Fifia Ardinanti; Rizki Ayu; Sudarto
Sriwijaya Journal of Forensic and Medicolegal Vol. 4 No. 1 (2026): Sriwijaya Journal of Forensic and Medicolegal
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjfm.v4i1.254

Abstract

Introduction: Unexplained sudden death (USD) presents a persistent diagnostic challenge in forensic medicine, especially in regions where consumption of unregulated traditional medicines (TM) is widespread. The toxicological contribution of unregulated TM to USD remains poorly characterized in Indonesia, where jamu use is prevalent and a large proportion of herbal products are unregistered. Methods: A forensic autopsy-based cross-sectional study was conducted on 120 USD cases at Hospital X, Palembang, South Sumatra, from January 2020 to December 2024. Postmortem femoral blood and liver tissue were screened by liquid chromatography-tandem mass spectrometry (LC-MS/MS) using a validated 85-compound panel covering alkaloids, heavy metals, pyrrolizidine alkaloids, aristolochic acid, and pharmaceutical adulterants. Sixty cases with verified TM use were compared with 60 non-TM user controls frequency-matched by age decade and gender. Latent class analysis (LCA) was applied for subgroup classification. Results: Alkaloids were detected in 75.0% of TM users versus 18.3% of controls (OR 13.36, 95% CI 5.62–31.72, p < 0.001). Pyrrolizidine alkaloids and pharmaceutical adulterants showed the highest discriminatory capacity (OR 15.55 and 21.00, respectively). Cardiac death was significantly more frequent in TM users (78.3% vs. 41.7%, p < 0.001). LCA identified three distinct toxicological subgroups: Class I (High Toxin Load, n=40), Class II (Moderate, n=36), and Class III (Low Toxin Load, n=44). Multivariate logistic regression, adjusted for age, BMI, hypertension, and toxicological findings, confirmed TM use as an independent predictor of cardiac death (adjusted OR 2.18, 95% CI 1.07–4.42, p = 0.031). Conclusion: These findings support the incorporation of TM-specific toxicological screening into standard forensic autopsy protocols and provide evidence for strengthened regulatory oversight of unregistered herbal products in Indonesia.
Co-Authors Abd El Nasser Brian Edgar Wicaksana Fifia Ardinanti Mohammad Arfin Sudarto