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Association Between Cervical Cancer Stage and Sexual Dysfunction as a Side Effect of Radiotherapy in Patients at Margono Soekardjo Hospital, Purwokerto Utomo, Aditya; Putri Susilo, Artha Falentin; Armawan, Edwin; Sutrisno, Sutrisno; Marlina, Dina; Adinda Adriansyah, Putri Nadhira
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 1 Maret 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i1.761

Abstract

Objective: This study aims to determine the side effects of radiotherapy on sexual function and its association with cancer staging in cervical cancer patients at Margono Soekardjo Hospital in 2017-2022.Methods: This research uses a cross-sectional analysis with a retrospective data collection method. The data collected include primary data from FSFI questionnaire results and secondary data from medical records containing demographic data, cervical cancer stage, and treatment given to cervical cancer patients at Margono Soekardjo Hospital, Purwokerto. Results: There were 79 subjects with a mean age of 48.8 ± 10 years old, with the most prevalent age group being 45-59 years old. The majority of patients were at stage IIB (45.57%). The mean FSFI score obtained was 27.31 ± 14.69, with 46 patients (58%) having sexual dysfunction. Based on the results of the Chi-Square test, there is no significant relationship between the stage of cervical cancer and sexual function (p=0.586). Conclusion: The study results show a high incidence of sexual dysfunction among cervical cancer survivors, particularly in those with an average age of 48.8 years and most commonly diagnosed at stage IIB. Radiotherapy significantly impacted sexual function, with an average FSFI score of 27.31. Regular sexual function evaluations before and after radiotherapy are recommended to enable early management and reduce morbidity.Hubungan antara Stadium Kanker Serviks dan Disfungsi Seksual sebagai Efek Samping Radioterapi pada Pasien di Rumah Sakit Margono Soekardjo, PurwokertoAbstrakTujuan: Tujuan dari penelitian ini adalah untuk mengetahui efek samping radioterapi terhadap fungsi seksual serta hubungannya dengan stadium pada pasien kanker serviks di RS Margono tahun 2017-2022.Metode: Penelitian ini merupakan penelitian analitik cross-sectional dengan metode pengambilan data secara retrospektif. Data yang diambil merupakan data primer berupa hasil kuesioner FSFI serta data sekunder berupa rekam medis berisi data demografi, stadium kanker serviks, dan tatalaksana yang diberikan pada pasien kanker serviks di RS Margono yang selanjutnya dilakukan uji analisis Chi-Square. Hasil: Terdapat 79 pasien kanker serviks yang merupakan subjek penelitian dengan rerata usia 48,8±10 tahun dengan kelompok usia terbanyak 45 - 59 tahun. Mayoritas pasien berada pada stadium IIB sebanyak 36 pasien (45,57%). Rerata skor FSFI yang didapat 27,31±14,69 dengan 46 pasien (58%) memiliki disfungsi seksual. Berdasarkan hasil uji Chi-Square tidak terdapat hubungan yang sifgnifikan antara stadium kanker serviks dan fungsi seksual (p=0,586).Kesimpulan: Studi ini menemukan insidensi tinggi disfungsi seksual pada penyintas kanker serviks, terutama pada pasien dengan rata-rata usia 48,8 tahun dan mayoritas terdiagnosis pada stadium IIB. Radioterapi secara signifikan memengaruhi fungsi seksual dengan skor rata-rata FSFI sebesar 27,31. Evaluasi fungsi seksual secara rutin sebelum dan setelah radioterapi direkomendasikan untuk memungkinkan penanganan dini dan mengurangi morbiditas.Kata kunci: Disfungsi seksual, FSFI, Kanker serviks 
The impact of endometriosis towards the severity of anemia Nurjanah, Salsa Evva; Ningrom, Ira Citra; Purbowati, Mustika Ratnaningsih; Agatri, Norina; Poernomo, Megawati Al’badly Ponco Dewi; Marlina, Dina; Utomo, Aditya; Amri, Beni Samsul
Indonesian Journal of Health Science Vol 5 No 4 (2025)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v5i4.1597

Abstract

The purpose of this study was to investigate the relationship between endometriosis and anemia severity, along with other potential contributing factors. The study was conducted at Margono Hospital in Indonesia and involved patients with endometriosis who were enrolled from 2020 to 2024. Inclusion and exclusion criteria were applied, and statistical analyses, including odds ratios and prevalence ratios, were performed. The analysis revealed that women of reproductive age were significantly more likely to develop endometriosis, with an odds ratio of 3.033 [95% CI 1.703-5.403, p<0.001]. Increasing age contributed 0.9% to the likelihood of endometriosis, and parity was significantly associated with endometriosis, with nulliparous women having an odds ratio of 11.883 [95% CI 2.103-67.163, p<0.001]. No significant correlation was found between anemia severity and endometriosis, though moderate anemia was most likely in the case group [OR 0.744, 95% CI 0.520-1.063, p=0.613]. Although endometriosis did not significantly affect anemia severity in our study, further research is needed to explore the molecular impact of different types of endometriosis on erythropoiesis.