Article Per Year (5 Year)
p-Index From 2021 - 2026
1.066
P-Index
This Author published in this journals
All Journal Indonesian Journal of Global Health research KESANS : International Journal of Health and Science Journal of Applied Nursing and Health International Journal of Health and Pharmaceutical (IJHP) HelFin Journal
Angreni, Frisca
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search

 1 
Morphology Profile and PD-L1 Expression in Non-Small Cell Lung Cancer (NSCLC) Patients Nurprilinda, Marliana; Novelyn, Silphia; Siahaan, Sonya Trinur Veronika; Angreni, Frisca
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6167

Abstract

Lung cancer cases in Indonesia became the second highest with the highest mortality rate in 2022. Various advanced examinations such as histopathology and immunohistochemistry are performed to identify the morphological types of lung cancer. Histopathologically, lung cancer classified into two types are Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC). After histopathological examination, further immunohistochemical testing is required to help classify the subtype and identify therapeutic markers. One of the markers is the expression of Programmed Death Ligand 1 (PD-L1). Patients with this marker can receive anti-PD-L1 immunotherapy according to the specified criteria. This study determined the morphological profile and PD-L1 expression in patients with Non-Small Cell Lung Cancer (NSCLC) at Siloam MRCCC Semanggi Hospital between 2020 and 2022. The method used was descriptive with a retrospective approach by collecting data from the archives of the Anatomical Pathology Laboratory at Siloam MRCCC Semanggi Hospital. The population in this study comprised all patients diagnosed with NSCLC who underwent PD-L1 IHC testing at Siloam MRCCC Semanggi Hospital between 2020 and 2022. Data collection was conducted using a total sampling method, including all individuals who met the predefined inclusion and exclusion criteria. The final sample consisted of 91 patients diagnosed with NSCLC who had undergone PD-L1 IHC examination during the 2020–2022 period. A total of 91 patients including the inclusion and exclusion criteria were included in the data and analyzed. The analysis revealed that the age group 60-69 years accounted for 39.5% of cases, 54.9% of cases were male, 73.6% of cases had an adenocarcinoma morphology, and 54.9% of cases had a negative PD-L1. The incidence of NSCLC patients who underwent PD-L1 IHK examination based on age was dominated by the 60-69 year age group, and most of them were male with the most common diagnosis being adenocarcinoma morphology type and PD-L1 expression with negative values.
Trabeculectomy Surgery in Primary and Secondary Glaucoma: Retrospective Cross-sectional Analysis Christine, Reinne Natali; Tanong, Nicolas Dwiki; Rombe, Claudia Valoryn Iona; Angreni, Frisca
Journal of Applied Nursing and Health Vol. 7 No. 2 (2025): Journal of Applied Nursing and Health
Publisher : Chakra Brahmanda Lentera Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55018/janh.v7i2.333

Abstract

Background: Glaucoma remains a leading cause of permanent blindness worldwide, with elevated intraocular pressure (IOP) as the most modifiable risk factor. When medical therapy fails, trabeculectomy is often the preferred surgical option, though its effectiveness may differ based on the type of glaucoma. Primary glaucoma is typically idiopathic, while secondary glaucoma results from identifiable causes such as trauma, inflammation, or diabetes. Understanding these distinctions is essential for optimizing surgical outcomes and tailoring patient-specific treatment strategies. This study aims to determine whether there is a difference between the reduction in intraocular pressure in primary and secondary glaucoma after undergoing trabeculectomy surgery. Methods: This descriptive cross-sectional study used purposive sampling to select medical records of patients who underwent trabeculectomy at the Christian University of Indonesia Teaching Hospital from July 2021 to June 2022. A total of 30 patients were included. Inclusion criteria were patients diagnosed with either primary or secondary glaucoma who underwent trabeculectomy and had complete pre- and postoperative IOP data. Exclusion criteria included patients with previous glaucoma surgery, incomplete medical records, or less than one month of follow-up. The primary outcome was the percentage reduction in IOP one month postoperatively.. Results: The results showed that the percentage reduction in IOP within 1 month in primary glaucoma was 43.54%, whereas in secondary glaucoma, it was 41.87%. P value > 0.05 in all postoperative IOPs between primary glaucoma and secondary glaucoma. Conclusion: Trabeculectomy is still the first choice to reduce IOP, which has failed pharmacological treatments. However, there was no significant difference between decreased intraocular pressure in patients with primary and secondary glaucoma.
Spastic Lower Paraparesis Due To Multiple Ossification of The Ligamentum Flavum of Fusion and Tuberous Type In The Thoracolumbar Region In A 42-Year-Old Woman Septayudha Suryonegoro, Gregorius; Angreni, Frisca
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.462

Abstract

Ossification of the ligamentum flavum (OLF) is characterized by the replacement of ligamentum flavum tissue with mature laminar bone accompanied by hypertrophy. Although rare, its highest prevalence is reported among East Asian populations, predominantly affecting males under 50 years old, and most commonly found in the lower thoracic region. Clinically, OLF presents as a slowly progressive myelopathy, yet its precise pathogenesis remains unclear. Diagnostic imaging modalities include radiography, computed tomography (CT), and magnetic resonance imaging (MRI). This case report describes a 42-year-old female diagnosed with thoracolumbar OLF based on MRI examination. The patient presented with spastic paraparesis and hypoesthesia from both feet to dermatomes Th10–11 following a history of trauma. Lumbar radiography showed only lumbal spondylosis, while thoracolumbar MRI revealed nodular thickening of the ligamentum flavum from Th6–7 to Th12–L1, resulting in spinal canal stenosis and compression of the spinal cord. Additional degenerative findings included superior endplate degeneration of L4 and multiple intervertebral disc bulging. Neurological deficits indicated myelopathy and radiculopathy due to compression of the lateral corticospinal and spinothalamic tracts. The absence of spinal cord edema on MRI suggested a chronic onset. OLF frequently coexists with vertebral degenerative abnormalities, as observed in this patient. Based on the radiologic characteristics, the lesion represented several morphological types including extended, enlarged, fused, and tuberous forms. Laminectomy performed in this case resulted in gradual neurological recovery. In conclusion, OLF is a rare but important cause of progressive thoracic myelopathy that may lead to irreversible neurological impairment. MRI evaluation plays a crucial role in preoperative assessment of spinal canal stenosis and spinal cord compression.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN STUNTING PADA BALITA DI DESA PANGADEGAN KABUPATEN SUMEDANG: FACTORS RELATED TO THE INCIDENT OF STUNTING IN TODDLERS IN PANGADEGAN VILLAGE, SUMEDANG REGENCY Andriyani Risma Sanggul; Angreni, Frisca
HelFin Journal Vol. 3 No. 1 (2026): Januari
Publisher : Fakultas Vokasi Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/helfin.v3i1.6421

Abstract

Stunting merupakan gangguan pertumbuhan dan perkembangan pada anak yang terjadi akibat interaksi berbagai faktor. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berkaitan dengan kejadian stunting pada balita yang berdomisili di Desa Pangadegan. Penelitian menggunakan desain analitik dengan pendekatan potong lintang (cross-sectional) dan dilaksanakan pada bulan Mei 2023. Pengumpulan data dilakukan melalui pengisian kuesioner oleh responden serta pemeriksaan antropometri pada balita, yang meliputi pengukuran tinggi dan berat badan. Responden dipilih menggunakan teknik purposive sampling dengan total sampel sebanyak 170 orang. Hasil uji statistik Chi-Square menunjukkan bahwa kualitas air minum (p = 0,002), ketersediaan fasilitas limbah (p = 0,003), kadar hemoglobin ibu saat hamil (p = 0,002), asupan nutrisi ibu selama kehamilan (p = 0,005), riwayat berat badan lahir rendah (BBLR) (p = 0,0001), pemberian ASI eksklusif (p = 0,0001), serta penyakit infeksi (p = 0,0001) memiliki hubungan yang signifikan dengan kejadian stunting. Faktor-faktor tersebut berpotensi menjadi determinan penting dalam upaya pencegahan stunting pada anak.
The Relationship Between Random Blood Glucose Levels and The Incidence of Diabetic Foot Ulcers Nunu Prihantini, Nur; Rahmawati, Fri; Angelita Permata Sitorus, Zefeilyne; Jackson Yang, John; Angreni, Frisca
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.615

Abstract

Diabetes mellitus is a global health challenge characterized by an ever-increasing number of cases annually. The most feared chronic complication of diabetes mellitus is diabetic foot ulcer (DFU), which significantly increases the risk of amputation and mortality rates. This study aims to analyze the relationship between random blood sugar (RBS) levels and the incidence of DFU in type 2 diabetes mellitus patients at Paragon Hospital, Citeureup 2026. The research method used is an analytical observational design with a cross-sectional approach. A total of 54 subjects meet the inclusion criteria out of 109 type 2 diabetes mellitus patients. Medical record data were statistically analyzed using the Chi-Square test. The results indicated that DFU patients were predominantly male (53.7%) and belonged to the 46-55 age group (38.9%). Clinical findings showed that the majority of research subjects (88.9%) had high random blood sugar levels (≥ 200 mg/dL). Statistical test results yielded a p-value of 0.000 (p < 0.05), indicating a significant relationship between high RBS levels and the incidence of DFU. Based on the result the concluded that uncontrolled RBS levels are a primary trigger for DFU. Chronic hyperglycemia triggers vascular and nerve damage, which inhibits the tissue healing process in the feet. Optimal control of RBS levels is essential as a preventive measure to avoid amputation complications in type 2 diabetes patients.
Data Profile of Lipoma and Liposarcoma at the Anatomical Pathology Laboratory of Siloam MRCCC Semanggi Cancer Hospital Jakarta Gultom, Fajar Lamhot; Simanjuntak, Jonathan Savero; Angreni, Frisca
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 7 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i7.620

Abstract

Introduction: Soft tissue tumors arise from mesenchymal tissues, with lipoma and liposarcoma being common types derived from adipose tissue. Considering the increasing prevalence of tumors in Jakarta, updated data on these specific cases are essential for better diagnostic and preventive measures. Objective: This study aims to determine the data profile of lipoma and liposarcoma patients at the Anatomical Pathology Laboratory of Siloam Cancer Special Hospital MRCCC Semanggi Jakarta during 2018–2019. Method: This research used a descriptive method with a cross-sectional approach. Data were collected from secondary medical records of all patients diagnosed with lipoma and liposarcoma at the laboratory. Result and Discussion: The study identified 56 cases in total, consisting of 52 cases of lipoma (92%) and 4 cases of liposarcoma (8%). Lipoma was predominantly found in patients aged 40–60 years, consistent with global epidemiological trends, while liposarcoma cases remained rare but clinically significant due to their malignant nature. Conclusions: Lipoma is significantly more prevalent than liposarcoma at this facility. These findings provide baseline data for clinical management and further epidemiological studies in specialized cancer hospitals in Indonesia
Co-Authors Andriyani Risma Sanggul Angelita Permata Sitorus, Zefeilyne Gultom, Fajar Lamhot Jackson Yang, John Novelyn, Silphia Nurprilinda, Marliana Prihantini, Nur Nunu Rahmawati, Fri Reinne Natali Christine, Reinne Natali Rombe, Claudia Valoryn Iona Septayudha Suryonegoro, Gregorius Siahaan, Sonya Trinur Veronika Simanjuntak, Jonathan Savero Tanong, Nicolas Dwiki