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All Journal Media Farmasi Indonesia Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Reza Adityas Trisnadi
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Other

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Hubungan Antara Indeks Massa Tubuh (IMT) dengan Lama Rawat Inap: Studi terhadap Pasien SNH di Rumah Sakit Islam Sultan Agung Semarang Daiffa Rafif Santoso; Heny Yuniarti; Reza Adityas Trisnadi
Jurnal Anestesi Vol. 3 No. 2 (2025): Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v3i2.1773

Abstract

Stroke is the second leading cause of death after heart disease. This condition is thought to be related to risk factors such as hypertension, diabetes mellitus, smoking, and lack of physical activity. The existence of these risk factors can affect a person's BMI (Body Mass Index). This study aims to determine the relationship between BMI status and the length of hospitalization of SNH patients at Sultan Agung Islamic Hospital, Semarang. This study uses analytical observational research and cohort research design. Data collection was carried out prospectively through the measurement of LLA and knee height in SNH patients as well as patient medical record data. The medical record data taken is the length of hospitalization of SNH patients obtained from the date of admission to the date of discharge from the hospital. The number of samples studied was 65 patients using the non-probability sampling method with consecutive sampling that had met the inclusion and exclusion criteria. The research was conducted at Sultan Agung Islamic Hospital Semarang from October 2024 - January 2024. The results of bivariate data analysis using the contingency coefficient statistical test obtained a significance value of P=0.047 (P<0.05) so that it can be concluded that there is a significant relationship between BMI status and the length of hospitalization of SNH patients at Sultan Agung Islamic Hospital, Semarang. The level of closeness of the relationship with the contingency coefficient test in this study was obtained r = 0.239 (0.20-0.399) so it is said that the closeness of the relationship is weak. It can be concluded that there is a significant relationship between BMI and length of stay in SNH patients at Sultan Agung Islamic Hospital Semarang. The length of hospitalization in SNH patients is also influenced by the severity of comorbidities, so that SNH patients with a high level of comorbidity severity have a longer length of hospitalization.
Antibacterial Activity of Beyond Use Date 0.3% Ofloxacin Eye Drops against Pseudomonas aeruginosa Fariha firdi gadis; Rahayu Rahayu; Masfiyah; Reza Adityas Trisnadi
Media Farmasi Indonesia Vol. 21 No. 2 (2026): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v21i2.365

Abstract

Pseudomonas aeruginosa is a Gram-negative bacterium and a major cause of healthcare-associated ocular infections. The beyond-use date (BUD) of ophthalmic preparations is intended to ensure drug safety and efficacy. This study aimed to analyze the effect of the BUD of 0.3% ofloxacin eye drops on the growth of P. aeruginosa. This in vitro experimental study used a post-test only control group design. Samples were obtained by purposive sampling using P. aeruginosa colonies, with five samples in each time group. Antibacterial activity was evaluated by measuring inhibition zone diameters and analyzed using the Friedman test followed by the Wilcoxon test. The mean inhibition zone diameters at day 0, day 7, day 14, day 21, and day 28 were 37.4 mm, 34.2 mm, 31.6 mm, 30.0 mm, and 29.4 mm, respectively (p < 0.001). Statistically significant differences were observed among the BUD groups from day 0 to day 28 (p < 0.05); however, no significant difference was found between day 21 and day 28 (p > 0.05). The findings indicate that extended storage time may compromise the stability of the active pharmaceutical ingredient, thereby contributing to a measurable decline in antibacterial efficacy.
Co-Authors Daiffa Rafif Santoso Fariha firdi gadis Heny Yuniarti Masfiyah Rahayu Rahayu