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All Journal Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Sainteknol : Jurnal Sains dan Teknologi
Prastiyo, Danu
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Health Professions Medicine & Pharmacology Nursing Public Health Other

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Optimization Formula of Collagen Nanoemulgel from WasteMilkfish (Chanos chanos) Bones as Antiaging Nasyanka, Anindi Lupita; Tiadeka, pemta; Nur Imtihani, Hilya; Octaviary, Niken Laras; Prastiyo, Danu
Sainteknol : Jurnal Sains dan Teknologi Vol. 22 No. 2 (2024): December 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/sainteknol.v22i2.14768

Abstract

Climate change has negative impacts throughout the countries in the world, especially Indonesia, which has a tropical climate. Successful aging can be achieved by building individual self-confidence through prevention and skin aging. Indonesia is a producer of milkfish waste, reaching 5.4 tons/year, which is in line with the increasing center of "Otak-otak" milkfish souvenirs found in Gresik. The waste, especially fishbones, can be synthesized into collagen. The characteristic fishbone collagen waste are in the form of large porous sheets, while particle size is an essential factor in the absorption effectiveness of cosmetics. Therefore, Nanoemulgel is able to overcome this problem. This research aims to produce best collagen nanoemulgel from milkfish bone by physical evaluation with varying ratios of surfactant: cosurfactant in collagen nanoemulgel. The research method was done experimentally by comparing the components Tween 80: PEG 400 F1 (30:30), F2 (40:20), and F3 (35:15) through qualitative and quantitative physical characteristics using one-way anova. Evaluations whose results differ significantly are pH on the 7th day, spreadability, and viscosity. Research results show F2 is the best formula and meets physical stability specifications : particle size 3.89 nm, PDI 0.1906, zeta potential -0.2 mV, pH 4.7±0.04, viscosity 890.1± 4.26 cps, spreading 5.93±0.23 cm. 
Formulation and Physical Evaluation of Depilatory Cream from with Variation Concentrations of Turmeric (Curcuma longa) and Bromelain Enzyme Ratnasari, Diah; Na’imah, Janatun; Trikurniadewi, Nastiti; Agustin, Irani; Prastiyo, Danu
Viva Medika Vol 18 No 3 (2025)
Publisher : LPPM Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v18i3.2064

Abstract

The Indonesian cosmetics industry market is predicted to grow by 5.91% per year, including skin care products. One type of skin care is removing unwanted hair from the skin because this hair can interfere with appearance, especially for women. One way to remove this hair is by using hair removal cream (depilatory cream). One natural ingredient that has depilatory properties is turmeric. Depilatory cream also requires sulfhydryl protease enzymes that can break down the molecular structure of proteins contained in hair into amino acids. One protease enzyme is bromelain. The purpose of this study was to obtain the best formula for depilatory cream with varying levels of turmeric and bromelain enzymes based on physical evaluation results. The research method used was experimental research with stages of turmeric extraction, bromelain enzyme isolation, depilatory cream formulation, and physical evaluation of the depilatory cream. The results showed that Formula 1 was the best turmeric-based depilatory cream formula with bromelain enzyme based on physical evaluation results.
Co-Authors Agustin, Irani Diah Ratnasari Nastiti Trikurniadewi Nasyanka, Anindi Lupita Na’imah, Janatun Nur Imtihani, Hilya Octaviary, Niken Laras Pemta Tiadeka Yunitasari, Norainny