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The Role of Bacillus pseudomycoides Isolates and Bioinformatics Modeling for Modern Pharmaceutical Applications: A Literature Review Ananta, Yorasakhi; Fitri, Salsabila Dwi
Dinasti Health and Pharmacy Science Vol. 2 No. 3 (2025): Dinasti Health and Pharmacy Science (January 2025)
Publisher : Dinasti Research & Yayasan Dharma Indonesia Tercinta (DINASTI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/dhps.v2i3.1832

Abstract

This article presents a literature review on the role of Bacillus pseudomycoides isolates as protease enzyme producers and how bioinformatics modeling enhances their potential in modern pharmaceutical applications. B. pseudomycoides is known to produce proteases with superior characteristics such as temperature and pH stability, making them potential candidates for pharmaceutical formulations. Bioinformatics approaches such as protein structure modeling, molecular docking, and genomic analysis have accelerated the functional characterization of these enzymes. The combination of the utilization of microorganisms and computational approaches opens up new opportunities in drug development, wound therapy, and pharmaceutical biotechnology. This study recommends multidisciplinary integration in the utilization of microbial resources for future therapeutic needs.
The Role of Bacterial Protease Enzymes and In Silico Prediction on the Effectiveness of Medical Applications Muliawan, Adi; Ananta, Yorasakhi; Fitri, Salsabila Dwi
Dinasti Health and Pharmacy Science Vol. 2 No. 4 (2025): Dinasti Health and Pharmacy Science (April 2025)
Publisher : Dinasti Research & Yayasan Dharma Indonesia Tercinta (DINASTI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/dhps.v2i4.1841

Abstract

Bacterial protease enzymes have a wide range of medical applications, particularly in the treatment of infected wounds and therapy for protein digestion disorders. Proteases produced by bacteria such as Bacillus pseudomycoides show great potential for medical therapy due to their ability to break down proteins in the human body. In silico prediction using bioinformatics software such as AutoDock and PyMOL allows researchers to analyze the three-dimensional structure and molecular interactions of proteases with target substrates before conducting laboratory experiments. This article examines the role of bacterial protease enzymes in medical applications and the benefits of using in silico prediction to study the therapeutic potential of proteases. With a combined approach of experimentation and in silico analysis, the process of developing protease-based therapies can be more efficient and faster. This study emphasizes the importance of bioinformatics approaches in accelerating the discovery of enzyme-based medical therapies for future clinical applications.
Pengaruh Etika Bisnis dan Transparansi Informasi terhadap Kepercayaan Konsumen dalam Transaksi B2C di Indonesia: Kajian Literatur Fitri, Salsabila Dwi; Ananta, Yorasakhi
Jurnal Kewirausahaan dan Multi Talenta Vol. 3 No. 4 (2025): Jurnal Kewirausahan dan Multi Talenta (Oktober - Desember 2025)
Publisher : Siber Nusantara Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jkmt.v3i4.529

Abstract

Dalam era digital, model bisnis Business to Consumer (B2C) berkembang pesat seiring meningkatnya konsumsi daring di Indonesia. Kepercayaan konsumen menjadi elemen krusial dalam menjaga keberlangsungan hubungan jangka panjang antara pelaku usaha dan pelanggan. Artikel ini bertujuan mengkaji peran etika bisnis dan transparansi informasi terhadap kepercayaan konsumen dalam konteks transaksi B2C di Indonesia melalui pendekatan kajian literatur sistematis. Penelusuran dilakukan pada berbagai sumber ilmiah dari database daring seperti Google Scholar, Mendeley, dan jurnal nasional, dengan fokus pada penelitian yang terbit dalam lima tahun terakhir. Hasil kajian menunjukkan bahwa penerapan etika bisnis yang konsisten dan transparansi informasi yang tinggi berkontribusi signifikan terhadap peningkatan kepercayaan konsumen. Artikel ini menyimpulkan bahwa kedua faktor tersebut saling melengkapi dan perlu diintegrasikan dalam strategi pemasaran digital B2C agar tercipta loyalitas dan keberlanjutan usaha.