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Didi, A.
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Energy Physics

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Fluka Monte Carlo for Validating Low-Energy Neutron Capture Therapy Tissue with Boron and Gadolinium Bakolia, T. E.; Didi, A.; Sebihi, R.; Adambounou, K.; Hazou, E.
Atom Indonesia VOL 50, NO 1 (2024): APRIL 2024
Publisher : National Research and Innovation Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/aij.2024.1380

Abstract

Research Gap: Neutron Capture Therapy (NCT) represents a cutting-edge neutron-therapy technique for tumor treatment, but there is a gap in understanding the optimization of neutron dose deposition in tumor cells, particularly in tissues enriched with boron and gadolinium. Research Objective: This study aims to evaluate the dose deposited by thermal neutrons in adipose tissues enriched with boron and gadolinium, utilizing the Monte Carlo Fluka code. Research Methodology: The research employs Fluka, an open source Monte Carlo simulations to assess thermal neutron dose deposition in tissues. The focus is on boron and gadolinium-enriched tissues to understand their impact on neutron dose optimization. Results: Findings affirm the advantages of boron and gadolinium in enhancing neutron dose deposition within tissues. Fluka simulations demonstrate the strategic utilization of neutron properties, showcasing the potential for improved tumor management. The study highlights gadolinium's attractiveness, suggesting its promising application in clinical settings.
Carbone or Oxygen Therapy: A Comparative Dosimetric Study Using PHITS Code El Bekkouri, H.; Al Ibrahmi, E.; El-Asery, M.; Bardane, A.; El Mahjoub, C.; Didi, A.; Sadoune, Z.
Atom Indonesia Vol 50, No 2 (2024): AUGUST 2024
Publisher : National Research and Innovation Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/aij.2024.1352

Abstract

Compared to conventional radiotherapy (X-rays or γ-rays), charged particle therapy shows more potential in treating deep-seated and radio-resistant tumors. Currently, all centers that offer hadron therapy use proton or 12C ion. Ongoing research is exploring the possibility of using others heavier ions, such as oxygen ion 16O or helium ion 4He. In this study, Monte Carlo method was used employing the Particle and Heavy Ion Transport code System (PHITS), to examine the amount of dose deposited by incident particles of 12C ion with energies of 200 and 300 MeV/u, as well as 16O ions with energies of 237.5 and 358.5 MeV/u. In this study, we investigated the depth dose distribution of carbon and oxygen ion beams by comparing their energy deposition in a water phantom and the impact of secondary particles. When considering lower energies, oxygen ions are more advantageous than carbon ions as they have slightly higher peak input ratios. This property enables higher doses to be delivered to tumor targets or lower doses to healthy surrounding tissues.
Bibliometric Analysis of the Literature on Carbon Ion Therapy Using VOSviewer Software and Dimensions Database El Bekkouri, H.; Al Ibrahmi, E.; El-Asery, M.; Bardane, A.; Didi, A.; El Mahjoub, C.; Sadoune, Z.
Atom Indonesia Vol 50, No 2 (2024): AUGUST 2024
Publisher : National Research and Innovation Agency

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/aij.2024.1392

Abstract

This study aims to carry out a bibliometric assessment of the worldwide research literature and historical research results on carbon ion therapy for cancer treatment. To carry out this work, we used the VOSviewer software and the Dimensions database. The VOSviewer software tool examined 2,500 publications exported from the Dimensions database. The results show a notable upward trajectory in academic research on carbon ion therapy since 1994, with 2020 showing the highest volume of publications. “Biomedical and Clinical Sciences”, “Physical Sciences”, “Oncology and Carcinogenesis”, and “Medical and Biological Physics” are the most important research categories. “Physics in Medicine and Biology” and “Medical Physics” are the leading journals for research publications on carbon ion therapy. Scrutiny based on term occurrences demonstrates the shift in research interest towards carbon ion radiation therapy. The analysis of bibliographic couplings concerning different countries revealed that Japan is the most dynamic and prolific country based on the number of publications (659) and citations (13734), followed by Germany with 590 publications and 19679 citations. These analytical studies provide a thorough overview of academic publications dedicated to using carbon ions for tumor treatment. This data is anticipated to be highly valuable for researchers seeking to pinpoint the most recent developments and emerging trends in this field of research.
Co-Authors Adambounou, K. Al Ibrahmi, E. Bakolia, T. E. Bardane, A. El Bekkouri, H. EL Mahjoub, C. El-Asery, M. Hazou, E. Sadoune, Z. Sebihi, R.