Nur Amalinda
Universitas Muhammadiyah Makassar

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Perbandingan Efektivitas Paracetamol vs Ibuprofen dalam Manajemen Demam Dewasa: Analisis Berbasis Data Real-World Nur Amalinda; Haryanto Haryanto
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1300

Abstract

Fever is the body's response to infection or inflammation, which often indicates a certain medical condition. One common treatment for fever is the use of antipyretic drugs. The purpose of this study was to evaluate the effectiveness of antipyretic drugs in lowering body temperature in adult patients with fever. The method used was a clinical trial with a randomized controlled trial (RCT) design, involving 100 adult patients with fever ≥38°C. Patients were divided into two groups: the group receiving antipyretic drugs (paracetamol) and the placebo group. Body temperature measurements were taken every 2 hours for 24 hours after drug administration. The results showed that the group receiving antipyretic drugs experienced a significant decrease in body temperature compared to the placebo group (p <0.05). The side effects that appeared were relatively mild and not dangerous..