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POTENSI HERBAL INDONESIA DALAM BIDANG BEDAH ANAK: PENDEKATAN BIOMEDIK MOLEKULER TERHADAP PENYEMBUHAN LUKA, INFLAMASI, DAN IMUNOMODULASI Mashdarul Ma’arif; Riki Nova; Febianne Eldrian; Dhina Lydia Lestari; Khomeini Khomeini
Nusantara Hasana Journal Vol. 5 No. 12 (2026): Nusantara Hasana Journal, May 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i12.2036

Abstract

Herbal-based complementary therapy approaches have recently gained attention in pediatric surgery due to their potential to support wound healing, reduce inflammation, decrease oxidative stress, and accelerate tissue regeneration. Indonesia possesses rich biodiversity of medicinal plants that have the potential to be developed as adjuvant therapies based on evidence-based medicine. This article aims to review the potential of Indonesian herbal medicine in the context of pediatric surgery through a molecular biomedical approach, focusing on wound healing, anti-inflammatory, antimicrobial, and immunomodulatory mechanisms. The method used in this study was a narrative literature review by searching scientific articles from PubMed, Scopus, ScienceDirect, and Google Scholar databases published between 2015 and 2025. The review findings indicate that several Indonesian herbs, including turmeric (Curcuma longa), moringa leaves (Moringa oleifera), ginger (Zingiber officinale), aloe vera (Aloe vera), and temulawak (Curcuma xanthorrhiza), exhibit biological activities through the regulation of NF-κB, TGF-β, VEGF, and PI3K/Akt pathways, as well as modulation of inflammatory cytokines and oxidative stress. The bioactive compounds of these herbs have the potential to accelerate angiogenesis, fibroblast proliferation, collagen synthesis, and wound epithelialization. Molecular approaches suggest that Indonesian herbal medicine has promising potential as a complementary therapy in pediatric surgical patients, particularly in the management of postoperative wounds and tissue inflammation.
PENGARUH DUKUNGAN KELUARGA TERHADAP TINGKAT AKTIVITAS SEHARI-HARI LANSIA PASCA STROKE NON HEMORAGIK PUSKESMAS LUBUK BUAYA Fidiariani Sjaff; Rasti Andika Sari; Mashdarul Ma’arif
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1839

Abstract

Following a stroke, elderly individuals often experience increased dependence on others, resulting in reduced independence in performing activities of daily living (ADL). Consequently, post-stroke care requires substantial family involvement and support. This study aimed to examine the effect of family support on the level of daily activities among elderly patients after non-hemorrhagic stroke at Puskesmas Lubuk Buaya Padang. This research was conducted within the fields of geriatrics (Internal Medicine) and neurology in November 2023. An observational study with a cross-sectional design was employed, utilizing secondary data obtained from questionnaires and medical records. A purposive sampling technique was applied, and a total of 30 elderly respondents were included in the analysis. Univariate analysis was presented as frequency distributions, while bivariate analysis was performed using the chi-square test. The results demonstrated that the majority of respondents received high levels of family support (83.3%), while the remaining participants received moderate levels of support (16.7%). In addition, most elderly patients exhibited good levels of daily activity (86.6%), whereas 13.3% demonstrated moderate activity levels. Statistical analysis revealed a significant association between family support and the level of daily activities among elderly patients after non-hemorrhagic stroke (p = 0.01). In conclusion, elderly patients with non-hemorrhagic stroke at Puskesmas Lubuk Buaya Padang generally receive high family support, which is significantly associated with better performance of daily activities.
PERBANDINGAN WAKTU MOBILISASI PASCA ANESTESI SPINAL PADA PASIEN SECTIO CAESAREA DENGAN METODE ERACS DAN NON ERACS DI RSU HERMINA PADANG Anita Darmayanti; Mashdarul Ma’arif; Nadya Nabila Vedrin
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1847

Abstract

Cesarean section is a surgical procedure to deliver a fetus through an incision in the abdominal wall and uterus, which generally uses spinal anesthesia. One innovation to accelerate postoperative recovery is the Enhanced Recovery After Cesarean Surgery (ERACS) method, which integrates pre-, intra-, and postoperative management to accelerate patient mobilization. Assessment of motor recovery after spinal anesthesia can be measured using the Bromage Score. This study aimed to compare the time to achieve the Bromage Score as an indicator of patient mobilization after spinal anesthesia in cesarean section surgery with the ERACS method and non-ERACS at Hermina Padang General Hospital. This study used a comparative analytical design with a cross-sectional approach. The sample consisted of 36 patients who underwent cesarean section surgery with spinal anesthesia at Hermina Padang General Hospital, which were divided into two groups: 18 patients with the ERACS method and 18 patients with the non-ERACS method. Data were analyzed univariately and bivariately using the independent t-test if the data were normally distributed and the Mann-Whitney test if the data were not normally distributed. Most patients were aged 26–35 years (80.6%), with the majority being nulliparous and primiparous (38.9%), and the majority having never undergone a cesarean section (55.6%). The mean time to achieve the Bromage Score showed that the ERACS group recovered faster than the non-ERACS group. The test results showed no significant difference in Bromage Score 3 (p = 0.825), but significant differences in Bromage Score 2 (p = 0.039), Bromage Score 1 (p = 0.000), and Bromage Score 0 (p = 0.046). The ERACS method has been shown to accelerate lower extremity motor recovery after spinal anesthesia compared to the non-ERACS method in cesarean section patients at Hermina Padang Hospital.