Kaeng, Juneke J
Indonesian Socety of Obstetrics and Gynecology

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Maternal Serum Interleukin6 Level in Correlation with Preterm Delivery Noviyanti, Noviyanti; Tendean, Hermie M M; Kaeng, Juneke J
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.092 KB)

Abstract

Objective: To determine the correlation between maternal serum Interleukin-6 (IL-6) serum level with preterm delivery. Methods: We performed an observational cross-sectional study of 30 pregnant women between 21 to 36 week gestational age with and wthout labour (delivery) in Prof. Dr. RD. Kandou Hospital Manado. Samples were collected with consecutive sampling method. Data was analyzed using Mann-Whitney test with significance level of p
Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features Homenta, Christian; Wantania, John J; Kaeng, Juneke J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.884 KB) | DOI: 10.32771/inajog.v4i3.433

Abstract

Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sam Ratulangi/Prof. Dr. R. D. Kandou General Hospital Manado. The subjects consisted of 26 pregnant women with normal blood pressure and 26 women with severe features of preeclampsia. We took the patients’ history, general physical examination, and laboratory assessment. The blood samples were taken from normotensive women more than 20 weeks of pregnancy and preeclamptic women with severe features more than 20 weeks of pregnancy. The data obtained was processed using SPSS 20.0 software. We did the nonparametric Mann-Whitney test to analyze the relationship between heme oxygenase-1 (HO-1) level in normotensive pregnancy and preeclampsia with severe features. Result: The level of heme oxygenase-1 (HO-1) in normotensive pregnant women was at 3.24 (SD 0.58) ng/ml (95% CI 3.00-3.47), and the level of heme oxygenase-1 (HO-1) of preeclamptic women with severe features was 3.92 (SD 0.73) ng/ml (95% CI 3.62-4.21). The result of Mann-Whitney test showed p value of 0.001 which meant that there was significant difference in the level of heme oxygenase- 1 (HO-1) between normotensive women and pre-eclamptic women with severe features. Conclusion: There was the relationship between the level of heme oxygenase-1 (HO-1) and the incidence of preeclampsia with severe features. Keywords: heme oxygenase-1 (HO-1), normotensive pregnancy, preeclampsia with severe features
Levels of 25 Hydroxyvitamin D in Normotensive Pregnancy and Severe Preeclampsia Palinoan, Meynita; Kaeng, Juneke J; Suparman, Erna
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.254 KB) | DOI: 10.32771/inajog.v6i2.765

Abstract

  Objective: To determine the ratio of 25-hydroxyvitamin D levels innormotensive pregnancy and severe preeclampsia.   Methods: This study was an analytic cross-sectional study witht-test. The subject of this study consists of 17 samples normotensivepregnancy and 17 samples severe preeclampsia. This study wasconducted and evaluated from August 2016 until December 2016 atDepartment of Obstetrics and Gynecology Faculty of MedicineUniversitas Sam Ratulangi Prof. Dr. R.D. Kandou Hospital Manadoand satellite hospital in Manado. Samples were taken from serumas much as 5 ccs and were analyzed using CLIA at Prodia clinicallaboratory. Data were analyzed with SPSS version 20.0.   Results: By using the t- test, there were significant differences in25-hydroxyvitamin D levels between normotensive pregnancygroup (24.771  6.9567ng/ml) and severe preeclamptic group(17.712  3.7513ng/ml), p = 0.001.   Conclusion: Levels of 25-hydroxyvitamin D in normotensive pregnancysignificantly higher compared to severe preeclampsia so it canbe concluded that the levels of 25-hydroxyvitamin D were associatedwith preeclampsia.   Keywords: 25-hydroxyvitamin D, normotensive, severe preeclampsia
Secretory Leukocyte Protease Inhibitor in Preterm Labor and Pregnancy Sutiono, Ferriyanto; Kaeng, Juneke J; Loho, Maria FT
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (117.639 KB) | DOI: 10.32771/inajog.v6i3.778

Abstract

  Objective: To investigate the levels of secretory leukocyteprotease inhibitor (SLPI) in women with preterm labor andpregnancy.   Methods: SLPI level examination conducted to 32 samples ofpregnant women who meet the inclusion and exclusion criteria,consists of 16 preterm labor and 16 preterm pregnancy.Sample analysis carried out in Prodia Laboratory Jakarta. SLPIlevel examination used ELISA method. The obtained dataprocessed by SPSS software version 20.0 and discussed withexisting literature theory.   Results: Mean plasma SLPI level in patients with preterm laboris 30.319 ng/ml and median: 29.950 ng/ml with p value: 0.652,while the mean on preterm pregnancy is 45.975 ng/ml andmedian: 41.600 ng/ml with p value: 0.005.   Conclusion: There are significant differences of SLPI level betweenpreterm labor and preterm pregnancy. Keywords: preterm labor, preterm pregnancy, SLPI
Maternal Serum Interleukin6 Level in Correlation with Preterm Delivery Noviyanti, Noviyanti; Tendean, Hermie M M; Kaeng, Juneke J
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 4, October 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.092 KB) | DOI: 10.32771/inajog.v3i4.52

Abstract

Objective: To determine the correlation between maternal serum Interleukin-6 (IL-6) serum level with preterm delivery. Methods: We performed an observational cross-sectional study of 30 pregnant women between 21 to 36 week gestational age with and wthout labour (delivery) in Prof. Dr. RD. Kandou Hospital Manado. Samples were collected with consecutive sampling method. Data was analyzed using Mann-Whitney test with significance level of p
Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features Homenta, Christian; Wantania, John J; Kaeng, Juneke J
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.884 KB) | DOI: 10.32771/inajog.v4i3.433

Abstract

Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sam Ratulangi/Prof. Dr. R. D. Kandou General Hospital Manado. The subjects consisted of 26 pregnant women with normal blood pressure and 26 women with severe features of preeclampsia. We took the patients’ history, general physical examination, and laboratory assessment. The blood samples were taken from normotensive women more than 20 weeks of pregnancy and preeclamptic women with severe features more than 20 weeks of pregnancy. The data obtained was processed using SPSS 20.0 software. We did the nonparametric Mann-Whitney test to analyze the relationship between heme oxygenase-1 (HO-1) level in normotensive pregnancy and preeclampsia with severe features. Result: The level of heme oxygenase-1 (HO-1) in normotensive pregnant women was at 3.24 (SD 0.58) ng/ml (95% CI 3.00-3.47), and the level of heme oxygenase-1 (HO-1) of preeclamptic women with severe features was 3.92 (SD 0.73) ng/ml (95% CI 3.62-4.21). The result of Mann-Whitney test showed p value of 0.001 which meant that there was significant difference in the level of heme oxygenase- 1 (HO-1) between normotensive women and pre-eclamptic women with severe features. Conclusion: There was the relationship between the level of heme oxygenase-1 (HO-1) and the incidence of preeclampsia with severe features. Keywords: heme oxygenase-1 (HO-1), normotensive pregnancy, preeclampsia with severe features
Levels of 25 Hydroxyvitamin D in Normotensive Pregnancy and Severe Preeclampsia Palinoan, Meynita; Kaeng, Juneke J; Suparman, Erna
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 2 April 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.254 KB) | DOI: 10.32771/inajog.v6i2.765

Abstract

  Objective: To determine the ratio of 25-hydroxyvitamin D levels innormotensive pregnancy and severe preeclampsia.   Methods: This study was an analytic cross-sectional study witht-test. The subject of this study consists of 17 samples normotensivepregnancy and 17 samples severe preeclampsia. This study wasconducted and evaluated from August 2016 until December 2016 atDepartment of Obstetrics and Gynecology Faculty of MedicineUniversitas Sam Ratulangi Prof. Dr. R.D. Kandou Hospital Manadoand satellite hospital in Manado. Samples were taken from serumas much as 5 ccs and were analyzed using CLIA at Prodia clinicallaboratory. Data were analyzed with SPSS version 20.0.   Results: By using the t- test, there were significant differences in25-hydroxyvitamin D levels between normotensive pregnancygroup (24.771  6.9567ng/ml) and severe preeclamptic group(17.712  3.7513ng/ml), p = 0.001.   Conclusion: Levels of 25-hydroxyvitamin D in normotensive pregnancysignificantly higher compared to severe preeclampsia so it canbe concluded that the levels of 25-hydroxyvitamin D were associatedwith preeclampsia.   Keywords: 25-hydroxyvitamin D, normotensive, severe preeclampsia
Secretory Leukocyte Protease Inhibitor in Preterm Labor and Pregnancy Sutiono, Ferriyanto; Kaeng, Juneke J; Loho, Maria FT
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 3 July 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (117.639 KB) | DOI: 10.32771/inajog.v6i3.778

Abstract

  Objective: To investigate the levels of secretory leukocyteprotease inhibitor (SLPI) in women with preterm labor andpregnancy.   Methods: SLPI level examination conducted to 32 samples ofpregnant women who meet the inclusion and exclusion criteria,consists of 16 preterm labor and 16 preterm pregnancy.Sample analysis carried out in Prodia Laboratory Jakarta. SLPIlevel examination used ELISA method. The obtained dataprocessed by SPSS software version 20.0 and discussed withexisting literature theory.   Results: Mean plasma SLPI level in patients with preterm laboris 30.319 ng/ml and median: 29.950 ng/ml with p value: 0.652,while the mean on preterm pregnancy is 45.975 ng/ml andmedian: 41.600 ng/ml with p value: 0.005.   Conclusion: There are significant differences of SLPI level betweenpreterm labor and preterm pregnancy. Keywords: preterm labor, preterm pregnancy, SLPI