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All Journal Cermin Dunia Kedokteran
R. Prihandjojo Andri Putranto
Biochemistry Laboratory, Faculty of Medicine, Sebelas Maret University, Surakarta
Health Professions

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Pengaruh Ekstrak Buah Naga Merah (Hylocereus polyrhizus) terhadap Kadar HDL Tikus Wistar Model Sindrom Metabolik: Hasil Penelitian Valensia Putri Melliana; Jarot Subandono; Danus Hermawan; R. Prihandjojo Andri Putranto; Sarsono
Cermin Dunia Kedokteran Vol 51 No 10 (2024): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i10.1145

Abstract

Introduction: Metabolic syndrome is characterized by hypertension, central obesity, insulin resistance, and dyslipidemia. Hylocereus polyrhizus is known for its potential in treating metabolic syndrome. Method: Laboratory experimental study with pretest-posttest control group design. Thirty rats were divided into 5 groups: K1 and K2 as negative and positive control, K3, K4, and K5 as groups receiving red dragon fruit extract at doses of 60, 120, and 180 mg/200 gBW. Data were analyzed using one-way ANOVA, Tukey HSD test, paired T-test, and Pearson correlation. Results: The highest HDL levels were observed in K5, while the lowest was in K1. Pearson correlation revealed a strong relationship between the dose of Hylocereus polyrhizus and HDL levels. Conclusion: Hylocereus polyrhizus extract could significantly increase HDL level. In this study, the optimal dose was 180 mg/200 gBW.
Co-Authors Danus Hermawan Jarot Subandono Sarsono Valensia Putri Melliana