p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Jurnal EduHealth
Febriane Balafif, Felisa
Unknown Affiliation

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Non-Invasive Immunological Monitoring Using Saliva in Dental and Oral Health Research Najmi, Nuroh; Kuswandani , Faisal; Rafisa, Anggun; Febriane Balafif, Felisa
Jurnal EduHealth Vol. 16 No. 03 (2025): Jurnal EduHealt, Edition July - September , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Saliva plays vital roles in oral and systemic health and is emerging as a valuable tool in biomedical research. It contains bioactive components such as cytokines, enzymes, and immunoglobulins that reflect immune status, making it a promising non-invasive diagnostic fluid. A literature review was conducted using PubMed and Google Scholar Science Direct (2015–2025) with keywords related to saliva, immunological markers, and oral health. Studies included were original research on human subjects. Articles were screened following PRISMA guidelines. Salivary biomarkers such as IL-6, TNF-α, IL-17A/F, IFN-γ, CRP, calprotectin, IP-10, MCP-1, NT-proBNP, IL-1β, IL-2, IL-8, and sTNFRII have been linked to oral cancer, periodontitis, diabetes, autoimmune disorders, cardiovascular disease, and viral infections. Studies showed that these markers reflect both local inflammation and systemic immune responses. Saliva captures immune activity through pathways like Th17, TNF, and JAK/STAT signaling. Its non-invasive nature, molecular stability, and compatibility with modern analysis techniques (e.g., transcriptomics and proteomics) make it ideal for monitoring disease progression and immune function. The presence of stable biomarkers like cytokines, acute-phase proteins, and cardiovascular indicators in saliva supports its diagnostic relevance.Saliva offers a practical, non-invasive approach to immunological monitoring. With proven biomarkers for various diseases, it holds strong potential for future diagnostic and research applications.
Malnutrition and oral Health in Elderly: a Narrative Review Anggraini, Jamas Ari; Najmi, Nuroh; Rafisa, Anggun; Febriane Balafif, Felisa; Sari, Kartika Indah
Jurnal EduHealth Vol. 16 No. 04 (2025): Jurnal EduHealt, Edition October-December , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aging process is generally defined as the accumulation of various changes that occur in cells and tissues as we age. According to the World Health Organization (WHO), an elderly individual is defined as a person who has reached or surpassed 60 years of age. Changes in conditions experienced by the elderly are not only physical changes, but also social and psychological changes. These changes influence each other and interact with other factors, which have an impact on the health conditions of the elderly, including appetite regulation which indirectly also has an impact on nutritional status in elderly. As we already know, nutrition is an important component for the elderly that affects the entire aging process and the general health condition of the elderly, including their oral health. Oral health and nutrition themselves have a multidirectional relationship. This relationship is manifested in the oral cavity, including plaque formation, dental caries, periodontal disease and other oral conditions. It is imperative for clinicians to comprehend the interplay between oral health and nutrition, as this knowledge is crucial for the effective management of elderly patients. This article focuses on the relationship between nutrition an oral health and its impact on older adults.