Article Per Year (5 Year)
p-Index From 2021 - 2026
3.77
P-Index
This Author published in this journals
All Journal Journal of Biomedicine and Translational Research Jurnal Analis Kesehatan Jurnal Kesehatan Tambusai Jurnal EduHealth Jurnal Sehat Indonesia (JUSINDO)
Nuroh Najmi
Anatomy Pathology, Department Of Oral Biology Faculty Of Dentistry Universitas Padjadjaran, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

Published : 26 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 26 Documents
Search

 1   2   3 
Gambaran Hiperurisemia pada Pria dan Wanita Obesitas Usia Produktif Otih Yuningsih; Adelia Febriyossa; Apriani Apriani; Nuroh Najmi; Agus Rohmat Hidayat
Jurnal Sehat Indonesia (JUSINDO) Vol. 4 No. 01 (2022): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (274.367 KB) | DOI: 10.59141/jsi.v4i01.41

Abstract

Hiperurisemia adalah keadaan terjadinya peningkatan kadar asam urat di atas normal. Bila keseimbangan asam urat di dalam darah terganggu maka dapat menyebabkan hiperurisemia salah satunya disebabkan oleh obesitas. Obesitas merupakan suatu keadaan tertimbunnya lemak dalam tubuh sebagai akibat berlebihnya asupan kalori dimana dapat memicu gangguan metabolisme yang menyebabkan asam urat dalam serum menjadi tinggi. Penelitian ini bertujuan untuk melihat gambaran hiperurisemia pada pria dan wanita obesitas di usia produktif 25-45 tahun. Penelitian ini penelitian dilakukan di Laboratorium Klinik Prodia Pluit pada bulan September – Oktober 2019. Sampel ditentukan dengan teknik purposive sampling. Sampel penelitian diperoleh sebanyak 80 orang. Hasil penelitian menunjukkan kadar hiperurisemia berdasarkan jenis kelamin yaitu pria lebih banyak mengalami hiperurisemia sebanyak 24 orang (53%) dan wanita 15 orang (43%). Kadar hiperurisemia berdasarkan usia menunjukkan usia 31-35 tahun paling banyak menderita hiperurisemia sebanyak 17 orang (55%). Kadar hiperurisemia berdasarkan pendidikan didapatkan kelompok pendidikan lulusan SMU yang paling banyak menderita hiperurisemia sebanyak 7 orang (88%) dan pemeriksaan kadar hiperurisemia berdasarkan riwayat genetika sebanyak 11 orang (69%). Dapat disimpulkan bahwa pada pria dan wanita yang mengalami obesitas di usia produktif memiliki kadar asam urat dalam batas normal.
Perbedaan Pemeriksaan Hitung Jumlah Trombosit Metode Impedans dan Optik pada Pasien Mikrositosis Anis Setyowati; Nuroh Najmi; Apriani Apriani
Jurnal Sehat Indonesia (JUSINDO) Vol. 4 No. 02 (2022): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.489 KB) | DOI: 10.59141/jsi.v4i02.44

Abstract

Ada dua metode untuk menghitung trombosit secara otomatis, yaitu metode impedansi dan metode optik, dan prinsipnya berbeda. Prinsip kerja dari metode impedansi adalah resistansi atau hambatan baterai tergantung pada pengaruh volume baterai terhadap arus tinggi, semakin besar baterai, semakin besar resistansi dan sebaliknya. Prinsip metode optik adalah hamburan cahaya yang terjadi ketika sel mengalir melalui celah dan berkas difokuskan ke area penginderaan di aperture/orifice. Penelitian ini bertujuan untuk mengetahui perbedaan jumlah trombosit yang diperiksa dengan metode impedansi dan optik pada pasien dengan mikrositosis di laboratorium klinik utama Bio Medika. Penelitian dilakukan mulai September 2019 hingga Oktober 2019. Sampel yang digunakan dalam penelitian ini adalah 122 pasien dari laboratorium klinik utama Bio Medika. Data yang diperoleh diuji normalitasnya kemudian diolah menggunakan uji statistik Wilcoxon. Dari hasil uji beda diperoleh p-value sebesar 0,000 (<0,05) yang berarti terdapat perbedaan nilai pemeriksaan impedansi dan optical platelet count pada pasien mikrositosis di laboratorium klinik utama Bio Medika. Jumlah trombosit metode impedansi lebih tinggi daripada metode optik. Kesimpulan Metode optik untuk jumlah trombosit pada pasien dengan mikrositosis
Oral Manifestations in Patients with Down's Syndrome and Management in Prosthodontics Achmad Syawqie; Jennifer Putri; Stephanie Yessica; Nuroh Najmi
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.58 KB)

Abstract

Down syndrome is an autosomal disorder associated with involving mental and physical changes. The types of craniofacial phenotypes and dental anomalies in individuals with Down syndrome have been described extensively, but further elaboration of their impact of oral and craniofacial conditions still needs to be understood. In addition, in prosthodontic, oral rehabilitation with complete dentures and implants in patients with Down's syndrome still needs to be studied. The aim of this review is to describe that the oral and craniofacial manifestations may occur in patients with Down syndrome, and determine the effectiveness of oral rehabilitation treatments in patients with Down syndrome. The article was   conducted of two databases and were limited to the period from January 2016 to February 2022 with a combination of the following keywords: “Down Syndrome”, “oral manifestation”, “implant”, “prosthodontic treatment”. The results obtained were 194 articles found at the beginning of the search in both databases, and the 16 full text articles were selected for further review and discussion. The results of this study shows that Down syndrome causes several oral and craniofacial manifestations, dental caries risk, higher periodontal disease, dental abnormalities, soft and occlusal tissue, and the presence of a craniofacial complex. In prosthodontics, the choice of using removable dentures or implants must be adjusted to each patient's condition. Down syndrome is an autosomal disorder that has oral and craniofacial manifestations that must be a concern for health practitioners, especially dentists. In prosthodontics, oral rehabilitation with either complete dentures or implants in patients with Down's syndrome is the right choice, but it is necessary to consider the complications that may occur.
The Role of Nutrition on the Immune Response Felisha Febriane Balafif; Anggun Rafisa; Faisal Kuswandani; Nuroh Najmi
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.861 KB)

Abstract

The immune system reaction against infections and other foreign substances is known as the immune response. Nutrition is a critical component in the modulation of the immune system, hence the importance of a balanced diet. Better nutrition improves health, reinforces the immune system, contributes to longevity, and decreases the chance of non-communicable diseases. Thus, nutrition, health, and immune system are strongly connected. The aim of the present study is to evaluate current knowledge on the role of nutrition on the immune response. The article was conducted of two databases and were limited to the period from January 2018 to April 2023 with a combination of the following keywords: “role" and "nutrition" and "immune response. The results obtained were 17 articles found at the beginning of the search in both databases, and the 10 full text articles were selected for further review and discussion. The results of this study shows that immunonutrition plays a role in immune function. Nutrition such as vitamins A, B6, B12, C, D, E, and folate; and trace elements (zinc, iron, selenium, magnesium, and copper) play important and complementary roles in supporting both the innate and adaptive immune systems. The development and maintenance of our immune system are very intricately tied to our dietary pattern. Therefore, working on our food habits and improving our nutrition seem to be a pragmatic approach to strengthen our immune response. Multiple micronutrients play vital roles in supporting the immune response.
Early Childhood Caries Among Overweight and Obese Children Anggun Rafisa; Felisha Febriane Balafif; Nuroh Najmi; Faisal Kuswandani
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.313 KB)

Abstract

Dental caries and obesity are both global public health issues that can have an impact on overall systemic health. Despite numerous studies investigating the link between dental caries and obesity, the findings remain inconclusive. This review aimed to determine the relationship between overweight, obese and ECC, as well as the impact of other potential risk factors. Research articles were searched using electronic databases such as Pubmed and Scopus. The selection of studies was following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) protocols. The initial phase of searching for articles in databases yielded 1176 results. There were twenty-three articles that received full-text appraisals, and fourteen studies were eliminated for not meeting the eligibility criteria. Finally, the study included nine articles. Only one of the nine articles considered in this review was a cohort study. The years of publishing range from 2019 to 2023. The majority of the study settings (n=5) were in high-income countries. Five of the studies reviewed found no association between overweight or obesity and ECC, whereas four identified a significant association. Based on the findings of this review, the association between overweight, obesity, and ECC appears undetermined. The differences in the findings of the studies included in this review could be attributed to the various BMI indicators employed to define the nutritional status of children. Other risk factors such as family socioeconomic status, parental educational level, and parental awareness of oral hygiene and dental visits may influence the association between overweight, obesity, and ECC.
Efficacy of Local Anesthetic: A Narrative Literature Review and Clinical Update in Dentistry Faisal Kuswandani; Felisha Febriane Balafif; Nuroh Najmi; Anggun Rafisa
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.295 KB)

Abstract

Achieving adequate anesthesia in patients is one of the most important aspects of the practice of dentistry to control or eliminate of pain. Pain is one of the most commonly experienced symptoms in dentistry and is a major concern to the dentist. The most essential skill of all dental practitioners is the ability to provide safe and effective local anesthesia. Several local anesthetics are used by the dentist, lidocaine has been considered as the golden standard for local anesthetic agents in dentistry for years. Articaine and mepivacaine both relatively new anesthetic agents are now widely used too. The purpose of this article is to provide a pharmacological profile of the various local anesthetic formulations in current use and their technical considerations.
Oral Inflammation and The Role of Cytokine Nuroh Najmi; Faisal Kuswandani; Anggun Rafisa; Felisha Febriane Balafif
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.087 KB)

Abstract

Acute inflammation becomes chronic when inflammation prolongs. Oral inflammation can develop become chronic and can be serious disease. Cytokines are small secreted proteins released by cells have a specific effect on the interactions and communications between cells. Based on studied that cytokine can be one of markers of inflammation. In many diseases cytokines can be biomarkers of inflammation and recently many studies use cytokines as one of the biomarkers in additional examination for their studies
The Role Of Entamoeba Gingivalis In Periodontal Disease: A Literature Study Emma Rachmawati; Rizky Farida Berlian; Ina Hendiani; Nuroh Najmi; Achmad Syawqie
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (487.628 KB)

Abstract

Background: Periodontal disease can affect the supporting structures of the teeth and can cause tooth loss. Periodontal disease is caused mainly by bacteria in dental plaque, but protozoa can also be found in deep pockets. The most common protozoa existing in periodontal disease is Entamoeba gingivalis. This study aims to determine the role of E. gingivalis in periodontal disease. Method: This research was a rapid review which is a method of synthesizing and assessing existing research. Articles were searched using the PubMed database from February 2021 to April 2021 with inclusion criteria in English from 2010 to 2020 and discussing the presence of E. gingivalis in periodontal disease. Result: Articles that comply with the inclusion criteria of this study are 11 articles. The study designs included case-control, cross-sectional, cohort, and case series. All articles concluded that E. gingivalis was found in patients with periodontal disease. Conclusion: The presence of E. gingivalis in large numbers in inflamed periodontal tissues indicates that E. gingivalis has a role in the course of periodontal disease.
Effect of Myristica fragrans on PGC1α and Synaptophysin Expression in Male Wistar Rats Hippocampus Veronica, Fifi; Goenawan, Hanna; Bahjah, Firda Hanan; Najmi, Nuroh; Lesmana, Ronny
Journal of Biomedicine and Translational Research Vol 10, No 1 (2024): April 2024
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v10i1.19959

Abstract

Background: Nutmeg is an indigenous plant from Indonesia that has been used extensively in herbal treatment. Nutmeg seed extract (NuSE) contains the active compound macelignan, which exhibits pharmacological activities. A previous study stated that NuSE is PPARγ or peroxisome proliferator-activated receptor gamma agonist that potentially enhances synaptic signal modulation. PPARγ activation can activate PGC1α or peroxisome proliferator-activated receptor gamma coactivator-1 alpha as the primary regulator of mitochondrial biogenesis. Mitochondria are involved in synaptic transmission. Increased modulation of signals at synapses can increase neuroplasticity, potentially improving the brain's cognitive function, as seen by the amount of Synaptophysin in the synaptic vesicle membrane for evaluating synaptogenesis.Objective: This research demonstrates how nutmeg seed extract (NuSE) affects PGC1α and synaptophysin expression compared with DHA or docosahexanoieac acid, which has been evidenced to promote neurite growth.Methods: Twenty-four Wistar male rats aged eight weeks were divided into four groups (control, PGA group, NuSE group, and DHA group). The treatment group was administered for 12 weeks using a gavage. After that, the rats were sacrificed, and the hippocampus neurons were collected. The PGC1α and Synaptophysin mRNA expression was measured using semiquantitative reversed PCR, visualized with electrophoresis, and then quantified with ImageJ.Results: This study showed that NuSE increased synaptophysin and PGC1α mRNA expressions compared to the control group with significance statistic (p=0.017, p<0,05) in synaptophysin expression but did not increase PGC1α expression significantly (p=0.364, p>0,05).Conclusion: In conclusion, nutmeg seed extract (NuSE) impacts synaptogenesis in synaptophysin expression to modulate synaptic transmission.
Pemeriksaan Cea dan M2PK Sebagai Tes Skrining Pada Kanker Kolorektal Murti, Evivana Pranika; Najmi, Nuroh; Apriani, Apriani; Setyawati, Rina
Jurnal Analis Kesehatan Vol. 10 No. 1 (2021): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v10i1.2720

Abstract

Kanker memiliki ciri mempertahankan sinyal proliferatif, menghindari penekan pertumbuhan, terjadi invasi dan metastasis, menginduksi angiogenesis, memungkinkan replikatif yang immortal, dan melawan kematian sel. Kanker kolorektal (CRC) merupakan hubungan kompleks dari sel tumor, sel non-neoplastik, dan sejumlah besar mikroorganisme. Deteksi dini pada awal lesi dapat menurunkan mordibitas dan mortilitas keganasan, sehingga penting dilakukan skrining. Pemeriksaan CEA dan M2PK dapat dilakukan sebagai tes skrining yang dilakukan di laboratorium. Beberapa Laboratorium sering kali hanya melakukan 1 pemeriksaan saja seperti CEA tanpa M2PK. Penelitian ini bertujuan untuk mengetahui perbedaan antara pemeriksaan CEA dan M2PK sebagai tes skrining kanker kolorektal. Penelitian ini dilakukan menggunakan metode komparatif. Penelitian dilakukan pada bulan Maret-Mei 2020 di Laboratorium Multilab Rawamangun. Sampel penelitian berasal dari 30 orang subjek yang dipilih berdasarkan kriteria harus melakukan pemeriksaan CEA dan M2PK secara bersamaan. Hasil uji statistik menggunakan uji Mann-Whitney diperoleh hasil p value 0,000. Hasil analisa tersebut menujukkan adanya perbedaan yang signifikan antara pemeriksaan CEA dan M2PK sebagai diagnosis kanker kolorektal. Pemeriksaan CEA dan M2PK dapat digunakan sebagai tes skrining awal pada pemeriksaan kanker kolorektal.
Co-Authors Achmad Syawqie Agus Rohmat Hidayat Anggraini, Jamas Ari Anggun Rafisa Anis Setyowati APRIANI Apriani Apriani Bahjah, Firda Hanan Balafif, Felisa Febriane Balafif, Felisha Faisal Kuswandani Faisal Kuswandani Falisha Febriane Balafif Febriane Balafif, Felisa Felisha Febriane Balafif Fifi Veronica Hanna Goenawan Ina Hendiani Jennifer Putri Kuswandani , Faisal Murti, Evivana Pranika Nurwijayanti Otih Yuningsih Rizky Farida Berlian Ronny Lesmana Sari, Kartika Indah Setyawati, Rina Stephanie Yessica