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All Journal MDJ (Makassar Dental Journal)
Wahyuningrat, Mitha Wijaya
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Dentistry

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Antibacterial effect of brown seaweed (Eisenia bicyclis) against Staphylococcus aureus: Efek antibakteri rumput laut cokelat (Eisenia bicyclis) terhadap Staphylococcus aureus Megumi, A. Apriliiqa; Benyamin, Roland Deavid; Wahyuningrat, Mitha Wijaya; Purnamasari, Daranisa Wulan; Rieuwpassa, Irene E.
Makassar Dental Journal Vol. 14 No. 1 (2025): Volume 14 Issue 1 April 2025
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v14i1.1109

Abstract

The oral cavity is one part of the body that is important to keep healthy; dental plaque which is an aggregation of bacteria, espe-cially those caused by Staphylococcus aureus, can cause various oral diseases. The brown alga Eisenia bicyclis has potential as an antibacterial agent due to the content of bioactive compounds such as phlorotannin, fucosterol, and fucoidan that have an-tibacterial, anti-inflammatory, and antioxidant activities. This article examines the antibacterial effect of E.bicyclis against S. au-reus in the context of oral health. The study showed that E.bicyclis extract inhibited the growth of S.aureus by the mechanism of increasing cell membrane permeability and inhibiting biofilm formation. In addition, phlorotannin compounds from E.bicyclis also showed synergistic effects in enhancing antimicrobial activity. It is concluded that E.bicyclis has the potential to be developed as a natural antibacterial therapy in oral health, especially to control the growth and plaque formation caused by S.aureus.
Co-Authors Benyamin, Roland Deavid Irene E. Rieuwpassa, Irene E. Megumi, A. Apriliiqa Purnamasari, Daranisa Wulan