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All Journal MDJ (Makassar Dental Journal)
Irene E. Rieuwpassa, Irene E.
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Dentistry

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Potential use of collagen extract from sea urchin for wound healing: Potensi penggunaan ekstrak kolagen dari landak laut untuk penyembuhan luka Ramadhan, Bagas Karunia; Amru, Muh Akmal; Masruroh, Bihaeri Itsna; Ika, Khaerunnisa; Rieuwpassa, Irene E.
Makassar Dental Journal Vol. 13 No. 3 (2024): Volume 13 Issue 3 Desember 2024
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v13i3.1078

Abstract

Wound healing in oral tissues requires a series of processes to close the wound and prevent infection. Sea urchin (SU) collagen can be utilised in biomedical applications such as periodontal tissue regeneration and wound healing in oral and maxillofacial surgi-cal treatments. Research shows that marine-sourced collagen can promote wound healing and skin regeneration in animals. This paper explores the potential of SU collagen as a biomaterial for wound healing applications in oral tissues. This collagen is sourced from marine connective tissues such as echinoderms and SU. Further research is needed to understand the potential of marine-sourced collagen in wound care and tissue regeneration in humans. The SU collagen shows favourable mechanical properties and potential for sustainable production. The SU collagen is promising for use in wound healing and tissue regeneration especially in oral tissues. It is concluded that SU collagen extract can accelerate wound healing and reduce scar tissue formation.
Antibacterial effect of brown seaweed (Eisenia bicyclis) against Staphylococcus aureus: Efek antibakteri rumput laut cokelat (Eisenia bicyclis) terhadap Staphylococcus aureus Megumi, A. Apriliiqa; Benyamin, Roland Deavid; Wahyuningrat, Mitha Wijaya; Purnamasari, Daranisa Wulan; Rieuwpassa, Irene E.
Makassar Dental Journal Vol. 14 No. 1 (2025): Volume 14 Issue 1 April 2025
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v14i1.1109

Abstract

The oral cavity is one part of the body that is important to keep healthy; dental plaque which is an aggregation of bacteria, espe-cially those caused by Staphylococcus aureus, can cause various oral diseases. The brown alga Eisenia bicyclis has potential as an antibacterial agent due to the content of bioactive compounds such as phlorotannin, fucosterol, and fucoidan that have an-tibacterial, anti-inflammatory, and antioxidant activities. This article examines the antibacterial effect of E.bicyclis against S. au-reus in the context of oral health. The study showed that E.bicyclis extract inhibited the growth of S.aureus by the mechanism of increasing cell membrane permeability and inhibiting biofilm formation. In addition, phlorotannin compounds from E.bicyclis also showed synergistic effects in enhancing antimicrobial activity. It is concluded that E.bicyclis has the potential to be developed as a natural antibacterial therapy in oral health, especially to control the growth and plaque formation caused by S.aureus.
Co-Authors Amru, Muh Akmal Benyamin, Roland Deavid Ika, Khaerunnisa Masruroh, Bihaeri Itsna Megumi, A. Apriliiqa Purnamasari, Daranisa Wulan Ramadhan, Bagas Karunia Wahyuningrat, Mitha Wijaya