Naurah, Ghina Nurjihan
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Impact of Soursop Leaf Decoction on Blood Pressure in Individuals with Hypertension: A Systematic Literature Review Rosalina, Dela Gita; Nurazizah, Tsaniya; Naurah, Ghina Nurjihan; Supriadi, Dedi; Noviati, Elis; Kusumawaty, Jajuk
Genius Journal Vol. 6 No. 1 (2025): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v6i1.530

Abstract

Introduction: Hypertension remains a leading global health concern, significantly increasing the risk of cardiovascular morbidity and mortality. Interest in natural therapies has grown, including the use of Annona muricata (soursop) leaf decoction, which is hypothesized to exert antihypertensive effects through its bioactive compounds. Objective: This systematic review aims to evaluate the efficacy of Annona muricata leaf decoction in reducing blood pressure among individuals with hypertension. Methods: A comprehensive literature search was conducted across four databases—PubMed, ProQuest, Garuda, and JSTOR—for studies published between 2021 and 2025. Inclusion criteria focused on studies involving hypertensive individuals treated with soursop leaf decoction, with outcomes measured using manual or digital sphygmomanometers. The selection process adhered to PRISMA guidelines. Data extraction and quality appraisal were independently performed by two to three reviewers using the CASP checklist. Extracted data included study characteristics, intervention details, duration, frequency, and delivery methods. Results: A total of 16 studies involving 322 participants were included. Findings consistently demonstrated that soursop leaf decoction significantly reduced both systolic and diastolic blood pressure. The observed antihypertensive effects are attributed to flavonoids and potassium, which contribute to vasodilation. The most effective regimen was consumption twice daily over a 7–8 week period. Conclusion: Annona muricata leaf decoction shows promising potential as an adjunctive, non-pharmacological intervention for managing hypertension. It offers a cost-effective and accessible alternative, especially in low-resource settings. Nonetheless, further clinical trials are needed to determine standardized dosages and assess interactions with conventional antihypertensive medications.
Efficacy of Guava Leaf Decoction in Lowering Blood Glucose in Diabetes Mellitus: A Systematic Review Naurah, Ghina Nurjihan; Oktaviani, Sophia; Rosalina, Dela Gita; Gandara, Purnama; Setiawan, Henri; Waluyo , Endrian Mulyadi Justisiya
Genius Journal Vol. 6 No. 1 (2025): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v6i1.532

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Introduction: Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels due to insulin resistance or insufficient insulin secretion. The rising global prevalence of DM has led to increased interest in alternative therapies, including herbal remedies such as guava leaf decoction, which is believed to possess hypoglycemic properties. Objective: This systematic review aims to evaluate the efficacy of guava leaf decoction in reducing blood glucose levels in patients with diabetes mellitus. Methods: A comprehensive literature search was conducted across four databases—PubMed, ProQuest, Garuda, and JSTOR—for studies published between 2020 and 2024. Inclusion criteria were studies involving diabetic patients receiving guava leaf decoction as an intervention, with outcomes measured in terms of blood glucose levels using glucometers. The selection and quality appraisal of studies were independently performed by two to three reviewers, following the PRISMA guidelines. The CASP checklist was used for methodological quality assessment. Extracted data included study authors, intervention details, facilitators, setting, session frequency, duration, and delivery method. Results: Eight eligible studies comprising a total of 229 participants were included. The findings consistently demonstrated that guava leaf decoction significantly reduced blood glucose levels. Effective regimens included twice-daily administration for 7 days or once daily (250 ml) for 14 days. Benefits were observed in both diabetic and obese individuals. Conclusion: Guava leaf decoction shows potential as a complementary therapy in the management of diabetes mellitus by naturally lowering blood glucose levels. Further clinical trials are recommended to confirm its efficacy and safety.
Holistic Care for Reducing Pain Intensity among Individual with Rheumatoid Arthritis: A Systematic Literature Review Nurazizah, Tsaniya; Naurah, Ghina Nurjihan; Oktaviani, Shopia; Hidayat, Nur; Setiawan, Henri; Kusumawaty, Jajuk; Suhanda, Suhanda
Genius Journal Vol. 7 No. 1 (2026): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v7i1.834

Abstract

Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disorder marked by persistent joint inflammation that causes pain, stiffness, and impaired mobility. While pharmacological treatment helps manage symptoms, some patients experience side effects or inadequate pain control. Therefore, holistic approaches involving psychological, lifestyle, and physical therapies are increasingly considered to support overall well-being and complement medical management. Objective: This systematic review aims to assess the effectiveness of holistic interventions in reducing pain intensity among individuals with RA. Method: A systematic search of six databases PubMed, ProQuest, Garuda, JSTOR, ScienceDirect, and Wiley was conducted for studies published between 2020 and 2024. Eligible studies included RA patients whose pain intensity was measured using validated tools such as the Numerical Rating Scale (NRS), Visual Analog Scale (VAS), or McGill Pain Questionnaire (MPQ). Two independent reviewers performed study selection and data extraction, while quality assessment followed PRISMA guidelines and the CASP Checklist. Results: Eleven studies comprising 607 participants met the inclusion criteria. The findings showed that holistic interventions including warm ginger compresses, Swedish massage, hand and foot massage, lavender aromatherapy, eucalyptus inhalation, Reiki therapy, and combined ginger compress with rheumatic exercise, were effective in reducing pain intensity in RA patients. Most studies reported significant improvements, with warm ginger compress being the most consistently effective method across various settings. Conclusion: Holistic approaches demonstrate meaningful benefits in reducing pain and supporting comfort in individuals with RA, particularly among older adults. Consistent application and appropriate duration of therapy enhance effectiveness. Overall, holistic care serves as a valuable complementary strategy that promotes patient-centered pain management and improves quality of life.