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All Journal Jurnal Kesehatan Andalas Jurnal Dunia Kesmas JOURNAL LA MEDIHEALTICO Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Ristyana, Sabira Husna
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Computer Science & IT Engineering Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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A 19-Years-Old Male with Left Maxillary Abscess: Case Report Ristyana, Sabira Husna; Aziizah, Reza Salmaa Nur; Adji, Iwan Setiawan
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5534

Abstract

Purpose: The purpose of this report is to present a case of a left maxillary abscess in a 19-year-old male, analyze its etiology, risk factors, clinical symptoms, diagnostic examinations, and the treatment provided. This report also highlights the importance of prevention and proper management to improve patient prognosis. Methodology: The methodology used in this report is a clinical case study. Data were collected through anamnesis, physical examination, and supporting examinations such as CT scan and histopathology. The patient’s management was analyzed based on existing medical theories and appropriate treatment was provided according to the patient’s condition. Results: The patient was diagnosed with a left maxillary abscess, presenting with persistent pain and swelling in the left cheek for two months.CT scan findings suggested left-sided sinusitis with a possible abscess, while histopathology confirmed chronic sinusitis.The patient received antibiotic therapy (Ceftriaxone and Metronidazole), symptomatic treatment (Santagesic, Methylprednisolone, and Ranitidine), and education on oral hygiene and follow-up care.The patient had a history of left maxillary surgery and smoking habits, both of which were identified as significant risk factors for developing the condition. Applications/Originality/Value: This report provides insights into the importance of early diagnosis and proper management in maxillary abscess cases.The findings can be useful for healthcare professionals to understand clinical signs and effective treatment approaches for similar cases.The study emphasizes the need for preventive measures, such as maintaining good oral hygiene and avoiding risk factors like smoking.
Relationship between Chronic Tonsillitis and Vascular Endothelial Growth Factor, Hypoxia, Biofilm and The Development of Therapies for Tonsillitis: Literature Review Febrian, Rizky; Ristyana, Sabira Husna; Adji, Iwan Setiawan
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5537

Abstract

Purpose: Tonsillitis is an inflammatory process that occurs in the palatine tonsils and can affect all ages, especially children. Chronic tonsillitis is a disease that is still a major health problem in the world. This disease can spread and cause percontinuitatum, hematogenous or lymphogenous complications. To date, tonsillectomy is the best option for tonsillitis management, but it is not the safest option because of the postoperative complications that can occur. With the advancement of health science, there are several studies have tried to find medicamentous treatments based pathogenetically against vascular endothelial growth factor, hypoxia and biofilms in tonsilitis that could be new modalities other than surgical therapy such as tonsillectomy. This scientific paper aims to determine the relationship between chronic tonsillitis and vascular endothelial growth factor, hypoxia and biofilm in the pathogenesis of tonsillitis and the development of medical therapy for chronic tonsillitis. Results: Microbial biofilms can lead of recurrent tonsillitis in population pediatric and adult. Using antibiofilm therapis can improve the efficacy of antimicrobials therapy and reduce the dose of systemically administered drugs. Elevated VEGF expression in the tonsil organ can be involved in the pathogenesis of recurrent or chronic tonsillitis. Anti-VEGF may be a potential treatment for tonsillitis by suppressing VEGF expression., in a hypoxia state may worsen the overall inflammatory status. Value: Our results show that there are several new modalities in the treatment of tonsillitis in the form of antibiofilms, and anti-VEGF.
Stevens Johnson Sindrome (SJS) in a Patient Presenting with Acute Pharyngitis Ristyana, Sabira Husna; Nadiroh, Ulayya Azzah; Adji, Iwan Setiawan
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5546

Abstract

Purpose: The purpose of this report is to present a case of Stevens Johnson Syndrome (SJS) in a Patient with Acute Pharyngitis, analyzing its etiology, risk factors, clinical symptoms, diagnostic tests, and treatment. This report also highlights the importance of prevention and proper management to improve the prognosis of the patient. Methodology: The methodology used in this report is a clinical case study. Data were collected through anamnesis, physical examination, and supporting examinations such as laboratorium. The patient's management was analyzed based on existing medical theories and appropriate treatment was provided according to the patient's condition. Results: The patient was diagnosed with acute pharyngitis with a differential diagnosis of Steven Johnson syndrome, with complaints of sore throat since 5 days ago. Blood laboratory results; leukocyte count 10.75 thousand/ul, leukocyte differential count; neutrophils 78.7% (H), lymphocytes 12.9% (L), eosinophils 0.9%, NLR 6.10% (H). Patients received therapies such as neurobion injections, metamizole injections, and dexamethasone injections. The patient was consulted to a dermatovenerology because the patient was suspected of having Steven Johnson Syndrome. So it is true that the patient has Steven Johnson Syndrome. The therapy given by the dermatovenerology was a 10 mg dexamethasone injection, followed by 5 mg every hour. Other therapies were stopped. The patient had a history of taking medication for headaches which was identified as a significant risk factor for developing the condition. Applications/Originality/Value: This report provides insights into the importance of early diagnosis and proper management in steven jhonson syndrome. sore throat most frequently recorded as a prodromal symptom for SJS, before the onset of skin rashes and oral cavity lesions. Painful skin rash when pressed and Nikolsky's sign are indicators to suspect Stevens-Johnson syndrome. Delayed management of SJS can be fatal, so misdiagnosis must be avoided. The findings can be useful for healthcare professionals to understand clinical signs and effective treatment approaches for similar cases. The study emphasizes the need for preventive measures. A thorough investigation of the drug usage history must be conducted to establish the diagnosis and determine the management plan. Management through multidisciplinary collaboration is highly expected for the patient's recovery.
Analysis of Nasal Septal Deviation Types on Sinusitis Incidence: Literature Review Ristyana, Sabira Husna; Povitasari, Povitasari; Andarista, Aprilia Intan; Adji, Iwan Setiawan
Journal La Medihealtico Vol. 6 No. 4 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i4.2187

Abstract

Nasal septal deviation is a common anatomical abnormality found in the general population and is thought to play a role in the pathogenesis of sinusitis. Some types of nasal septal deviation can impair sinus drainage and airflow, leading to inflammation and infection. However, there is no consensus on which type of septal deviation contributes most to sinusitis. Objective: This literature review aims to analyze and identify the types of nasal septal deviation that are most frequently associated with sinusitis. Methods: The data review was conducted using the PRISMA method, with data searches from PubMed, Google Scholar, ScienceDirect and Wiley with research data criteria between 2020-2024. The keywords used to search for data were "Type", "Nasal Septal Deviation", and "Sinusitis". A total of 23,943 articles were screened, with the final result being 20 articles that met the criteria for review. Results: Based on the review of the review in this study, nasal septal deviation (SND), especially types 3 and 5 according to the Mladina classification, contributes to chronic sinusitis through impaired ventilation and sinus drainage. Discussion : Nasal septal deviation (SND) is an anatomical abnormality that can interfere with airflow and sinus drainage, thus playing a role in the pathogenesis of sinusitis, especially types 3 and 5 according to the Mladina classification. These two types are often associated with osteomeatal complex obstruction and chronic mucosal irritation. The mechanisms involved include local hypoxia, mucociliary disorders, chronic inflammation, and changes in the microbiome.
Leukocytosis Fluctuation Despite Clinical Improvement In Peritonsillar Infiltrate: A Case Report Ristyana, Sabira Husna; Adji, Iwan Setiawan; Faqihudin, Fadli Rizal
Jurnal Dunia Kesmas Vol 15, No 1 (2026): Volume 15 Nomor 1
Publisher : Persatuan Dosen Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jdk.v15i1.23646

Abstract

Leukocytosis is an important indicator in assessing the inflammatory response to acute infections, including peritonsillar infiltrate, which represents an early stage preceding the formation of a peritonsillar abscess. However, an increased leukocyte count does not always correlate proportionally with clinical improvement. This case report presents an 11-year-old boy diagnosed with peritonsillar infiltrate, accompanied by odynophagia, mild trismus, and submandibular edema. Laboratory examinations revealed fluctuating leukocytosis, rising from 23,280/µL to 30,800/µL and then decreasing to 23,360/µL, despite significant clinical improvement. The patient initially showed a suboptimal response to ceftriaxone–metronidazole therapy but demonstrated marked improvement after the administration of meropenem. This phenomenon is presumed to result from the interplay between ongoing inflammatory activity, the pharmacologic effect of corticosteroids causing neutrophil demargination, and the physiological stress response during the healing phase. This case underscores the importance of a multidimensional interpretation of hematologic parameters when evaluating the success of therapy in acute infections and highlights the urgency of implementing antibiotic stewardship in response to increasingly complex patterns of antibiotic resistance.
Strategi pencegahan non-farmakologis pada rhinitis alergi dalam mengatasi keterbatasan terapi antihistamin jangka panjang: Systematic review Adji, Iwan Setiawan; Ristyana, Sabira Husna; Mahensa, Noval Gentha; Anggrahini, Witrishya; Nabilah, Aisyah; Nadhifa, Marshanda Ariella; Fatimah, Lina Nur; Nadzifa, Dhia Laila
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2685

Abstract

Non-pharmacological prevention strategies for allergic rhinitis in addressing the limitations of long-term antihistamine therapy: A systematic review Antihistamine therapy in Allergic rhinitis is generally the primary choice for symptom management. However, long-term use often presents side effects such as sedation, tolerance, and lack of control over allergen exposure. Non-pharmacological preventive strategies are important to explore as complementary and alternative approaches. Objective: To analyze effective non-pharmacological strategies for the prevention of allergic rhinitis. Methods: A literature search was conducted across electronic databases such as PubMed, Scopus, and Google Scholar, focusing on publications published between 2015 and 2024. The selected studies included experimental studies, systematic reviews, and clinical guidelines addressing non-pharmacological interventions for allergic rhinitis. The most frequently discussed non-pharmacological strategies included environmental controls (e.g., reducing exposure to dust, mites, and air pollution), nasal saline irrigation, mask use, lifestyle modifications, and patient education. Results: Several interventions have shown significant reductions in symptom scores and improvements in patients' quality of life, especially when combined with pharmacological therapy. Non-pharmacological approaches have significant potential as long-term management strategies for allergic rhinitis. Conclusion: The combination of education, environmental modifications, and physical interventions can reduce symptom frequency and the need for antihistamines. Keywords: allergic rhinitis, antihistamines, environmental modifications, non-pharmacological, prevention
Co-Authors Adji, Iwan Setiawan Andarista, Aprilia Intan Anggrahini, Witrishya Aziizah, Reza Salmaa Nur Faqihudin, Fadli Rizal FATIMAH, Lina Nur Febrian, Rizky Mahensa, Noval Gentha Nabilah, Aisyah Nadhifa, Marshanda Ariella Nadiroh, Ulayya Azzah Nadzifa, Dhia Laila Povitasari, Povitasari