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Correlation of Platelet Count, PDW, and MPV with Length of Stay in Children with Dengue Infection Faqihudin, Fadli Rizal; Puspitasari, Metana; Jatmitko, Safari Wahtu; Dewi, Listiana Masyita
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5510

Abstract

Purpose: The research aim to determine and analyze the correlation between platelet count, platelet distribution width, mean platelet volume and length of stay in children dengue virus patients. Methodology: This research used correlative observational study employed a cross-sectional design and included 48 children patients with dengue virus infection treated at PKU Muhammadiyah Sampangan Hospital, Surakarta. Platelet count, PDW, MPV, and LoS data were obtained from medical records. Statistical analysis to evaluate the correlation between these variables. Results: Results The study found platelet count (r = 0.28, p = 0.849), PDW (r = -0.110, p = 0.456), or MPV (r = 0.105, p = 0.477) no significant correlation with the length of stay. The result suggest that these platelet count, PDW, MPV are not acurate predictors of LoS in children dengue patients. Applications/Originality/Value: The platelet count, PDW, MPV are not reliable predictors the length of stay in children with dengue virus infection. This finding suggests for future studies, emphazie the need for a comprehensive clinical assessment rather than relying solely on platelet parameters when managing children dengue patients to predictors the length of stay in children with dengue virus infection and inform doctors in monitoring the course of dengue infection so that it is expected to reduce the incidence dengue infection in children.
Primary Health Care in Preliminary Hypertension Management: A Literature Review Irvan, Muhammad; Mahfud, Miftakhul Ulum; Mangkuluhur, Adhysta; Faqihudin, Fadli Rizal; Auliansyah, Jundan; Asyari, Rahima Galan
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5522

Abstract

Abstract Purpose: The purpose of the article is to evaluate and emphasize the role of primary health care (PHC) in managing hypertension. It systematically reviews the integration of various pharmacological, non-pharmacological, and technological strategies used in PHC to improve hypertension outcomes. By analyzing studies from different regions and methodologies, the article identifies effective interventions, challenges, and areas requiring improvement in hypertension management. Methodology: This review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standard statement. Our search strategy used electronic databases, namely Pubmed, Scopus, and Google Schoolar. Journal searches were conducted in November 2024. Pubmed and Scopus searches used the search keywords "Primary Health Care" OR "Primary Care" AND "Hypertension" AND "Management". Results: Our search strategy identified a total of 2698 articles. After full-text reading, 19 relevant journals were found. Applications/Originality/Value: The article's originality lies in its comprehensive review of primary health care's (PHC) role in managing hypertension, integrating recent evidence (2019–2024) from diverse regions. It highlights the importance of combining medications, lifestyle changes, and technology (e.g., telemonitoring, ABPM) while addressing barriers like poor access, low adherence to guidelines, and socio-economic disparities. By focusing on practical solutions, such as better training, patient education, and programs like Indonesia's PROLANIS, the article offers valuable insights for improving hypertension management, particularly in low-resource settings, emphasizing a holistic, actionable, and globally relevant approach.
Rhinosinusitis Kronis Yang Diperberat Dengan Anemia: A Case Report Adji, Iwan Setiawan; Ayuningrum, Nyovita; Ningtiyas, Devy Ayu; Faqihudin, Fadli Rizal; Al Farghani, Rayhan Fahrezi; Reanita, Ria
Jurnal Dunia Kesmas Vol 15, No 1 (2026): Volume 15 Nomor 1
Publisher : Persatuan Dosen Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jdk.v15i1.23647

Abstract

Chronic rhinosinusitis (CRS) is a ≥12-week inflammation of the paranasal sinuses influenced by anatomical and immunological factors. Iron-deficiency anemia (IDA) can worsen CRS through mucosal hypoxia, impaired ciliary function, oxidative stress, and reduced local immunity. A 15-year-old girl presented with bilateral nasal obstruction, facial pain, and difficulty clearing secretions. She had a history of heavy menstrual bleeding and showed hypochromic microcytic anemia (Hb 7.4 g/dL, serum iron 13 µg/dL, TIBC 385 µg/dL). Examination revealed bilateral inferior turbinate hypertrophy, right maxillary rhinosinusitis, and mild bilateral ethmoiditis. Inferior turbinate hypertrophy impaired sinus ventilation and drainage, leading to mucus retention and chronic inflammation. IDA further aggravated the condition by reducing mucosal oxygenation, weakening ciliary activity, and impairing phagocytic function. The patient underwent left inferior turbinate reduction first due to cross-obstruction, and received two units of PRC with gradual clinical improvement.Correction of anemia improved mucosal oxygenation and supported epithelial recovery after surgery. Overall, IDA contributes to worsening CRS, and its management is an essential component of comprehensive treatment to enhance healing and prevent recurrence.
Leukocytosis Fluctuation Despite Clinical Improvement In Peritonsillar Infiltrate: A Case Report Ristyana, Sabira Husna; Adji, Iwan Setiawan; Faqihudin, Fadli Rizal
Jurnal Dunia Kesmas Vol 15, No 1 (2026): Volume 15 Nomor 1
Publisher : Persatuan Dosen Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jdk.v15i1.23646

Abstract

Leukocytosis is an important indicator in assessing the inflammatory response to acute infections, including peritonsillar infiltrate, which represents an early stage preceding the formation of a peritonsillar abscess. However, an increased leukocyte count does not always correlate proportionally with clinical improvement. This case report presents an 11-year-old boy diagnosed with peritonsillar infiltrate, accompanied by odynophagia, mild trismus, and submandibular edema. Laboratory examinations revealed fluctuating leukocytosis, rising from 23,280/µL to 30,800/µL and then decreasing to 23,360/µL, despite significant clinical improvement. The patient initially showed a suboptimal response to ceftriaxone–metronidazole therapy but demonstrated marked improvement after the administration of meropenem. This phenomenon is presumed to result from the interplay between ongoing inflammatory activity, the pharmacologic effect of corticosteroids causing neutrophil demargination, and the physiological stress response during the healing phase. This case underscores the importance of a multidimensional interpretation of hematologic parameters when evaluating the success of therapy in acute infections and highlights the urgency of implementing antibiotic stewardship in response to increasingly complex patterns of antibiotic resistance.
The Sound Horeg Phenomenon: Health Impacts of Infrasound Exposure: A Literature Review Adji, Iwan Setiawan; Ayuningrum, Nyovita; Ningtiyas, Devy Ayu; Faqihudin, Fadli Rizal; Al Farghani, Rayhan Fahrezi; Reanita, Ria
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.2772

Abstract

The sound horeg phenomenon represents a cultural practice involving the use of high-power audio systems during social events in various regions of Indonesia, particularly East Java. While it serves as an important medium of entertainment, cultural expression, and local economic activity, exposure to excessive noise dominated by low-frequency noise (LFN) and infrasound raises public health concerns. This literature review aims to evaluate current scientific evidence regarding the biological, neurophysiological, psychological, and social impacts of infrasound exposure on humans. A comprehensive search was conducted in PubMed, Scopus, ScienceDirect, Google Scholar, and ProQuest for articles published between 2015 and 2025. The results show that moderate-intensity infrasound (≤90 dB) causes sleep disturbances, increased stress, and subtle neurological adaptations that can alter long-term cognitive function. Extreme exposure, such as to high-intensity sound (≥120 dB), carries a high risk of causing Noise-Induced Hearing Loss (NIHL), decreased memory function, and social isolation due to communication disorders. In addition to biological effects, psychological factors such as the nocebo effect play a role in the emergence of health complaints due to negative perceptions of loud noise. Therefore, a balance between preserving cultural values and protecting health needs to be achieved through sound intensity regulation, public education, and adaptive acoustic architectural design