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All Journal Indonesian Journal of Tropical and Infectious Disease Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Mubaraq, Syahrun El
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Computer Science & IT Earth & Planetary Sciences Engineering Health Professions Medicine & Pharmacology Public Health Social Sciences Other

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Case Report: Peptic Ulcer and Anemia Gravis Due to Over-the-Counter Anti-Inflammatory Drugs Misuse in Gout Arthritis Mubaraq, Syahrun El; Nawangasri, Andis Putri; Syabany, Muhammad Noer; Suling, Irmawati
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5541

Abstract

Background: Peptic ulcer disease (PUD) is a serious global health concern, often linked to nonsteroidal anti-inflammatory drugs (NSAIDs). Chronic, unsupervised NSAID use increases the risk of severe gastrointestinal complications, particularly in rural areas with limited healthcare access. Case Presentation: A 62-year-old male from a remote village presented with hematemesis, melena, and severe anemia (Hb 6.7 g/dL). He had a history of prolonged NSAID and steroid use for gout arthritis without medical supervision. Due to limited diagnostic facilities, the diagnosis of NSAID-induced peptic ulcer with anemia was based on clinical and laboratory findings. The patient received blood transfusions, proton pump inhibitors, gastroprotective agents, and urate-lowering therapy. His condition improved after seven days of hospitalization, and he was discharged with medication guidelines and follow-up care. Discussion: This case highlights the dangers of self-medication and the lack of awareness regarding NSAID-associated complications in underserved regions. Alternative pain management strategies, including colchicine and lifestyle modifications, should be prioritized to reduce reliance on NSAIDs. Conclusion: Chronic NSAID misuse can lead to life-threatening complications, as demonstrated in this case of peptic ulcer and anemia gravis. This report emphasizes the need for better patient education, medication supervision, and stricter regulations on over-the-counter drug sales, especially in rural settings.
Correlation between Probable or Non-Probable Leptospirosis with Laboratory Findings: Based on Leptospirosis Case Definition and Faine Criteria Citra Saputra, Rada; Mahmuda, Iin Novita Nurhidayati; Utami, Musrifah Budi; Pinakesty, Angiesta; Mubaraq, Syahrun El; Srirojanakul, Sirada
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.56564

Abstract

The incidence of leptospirosis is increasing globally, and developing countries are no exception. Leptospirosis cases are called the tip of the iceberg phenomenon, even though misdiagnosis, underdiagnosis, and underreporting still occur in health services. Thus, it leads to delays in leptospirosis treatment and may result in increased mortality rate from severe leptospirosis infection (Weil's disease). This study was to establish an accurate diagnosis by optimizing the Faine criteria. This study used an analytical observational design with a cross-sectional approach to examine faine criteria and laboratory examinations. We collected data from medical records from the Karanganyar General Hospital and the PKU Muhammadiyah Surakarta Hospital. We processed the data using SPSS version 25. The total number of samples was 42. They were divided into women (19%) and men (81%). Based on the definition category of leptospirosis cases, there were 2.4% probable group (score criteria faine part A 20-25) and 97.6% not-probable group (score criteria faine part A <20). Bivariate analysis (Chi-Square test) showed that there was no significant correlation between Faine Part A criteria and serological tests in both groups (p=0.874) as well as Hb (p=0.522), thrombocytopenia (p=0.265), leukocytosis (p=0.197), and neutrophilia (p=0.710). Loss of sodium and potassium didn’t show significant data (hyponatremia p=0.174; hypokalemia p=0.311; hypocalcemia p=0.131) not as in tropical diseases. The approach to diagnosis of leptospirosis cannot be performed using only Part A criteria, Faine, even though the patient was included in the probable definition category, even though the Faine Part A criteria score is 20-25 or ≥26.
Co-Authors Citra Saputra, Rada Iin Novita Nurhidayati Mahmuda Nawangasri, Andis Putri Pinakesty, Angiesta Srirojanakul, Sirada Suling, Irmawati Syabany, Muhammad Noer Utami, Musrifah Budi