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Journal : Asian Journal of Healthcare Analytics

Systematic Literature Review: Effectiveness of Insulin Combination Therapy with Glucagon-Like Peptide-1 (GLP-1) Incretin-Based Therapy in Patients with Type 2 Diabetes Mellitus Sibarani, Benly Levi Andreas; Utami, Putri
Asian Journal of Healthcare Analytics Vol. 3 No. 2 (2024): November 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v3i2.12310

Abstract

Diabetes mellitus remains an evolving metabolic and endocrine disease. Effective pharmacological management of type 2 DM is still a global concern. Insulin therapy often causes side effects of hypoglycemia, so other therapies are expected to be combined with insulin. The literature reviewed in this review used two databases, PubMed and Cochrane, based on objectives, clinical keywords, and choice of articles according to predetermined inclusion and exclusion criteria. The methodology was a systematic approach involving identification, analysis, synthesis, evaluation, and comparison of relevant literature. A total of two results were obtained showing that the composite of insulin-based therapy and GLP-1 therapy in patients with type 2 DM provides effective results to control the levels of blood sugar in type 2 DM patients.
Systematic Literature Review: The Effect of Breastfeeding on the Incidence of Stunting in Infants and Children Sibarani, Benly Levi Andreas; Utami, Putri
Asian Journal of Healthcare Analytics Vol. 3 No. 2 (2024): November 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v3i2.12166

Abstract

Child malnutrition affects children's health in terms of morbidity and mortality rates. Stunting remains a persistent nutritional issue among children that has yet to be effectively addressed. This study aims to examine the impact of breastfeeding on the incidence of stunting in infants and young children. This study reviewed literature from two databases, PubMed and Google Scholar, based on predetermined criteria. The methodology was conducted using a systematic approach from the literature. The results of the study obtained nine articles that met the criteria, then continued with a systematic review. Three studies showed the role of breastfeeding as a significant protective factor. Five studies identified a link between breastfeeding and stunting incidence, while another study found no such association. The presence of a significant relationship and the protective role of breastfeeding against stunting are crucial in efforts to lower the risk of stunting among toddlers and young children.
Microsurgical versus Conventional Inguinal Varicocelectomy: A Systematic Review of Fertility Outcomes and Recurrence Risk Putra, Bobby Aksanda; Sibarani, Benly Levi Andreas; Sinaga, Maeike Grestiana
Asian Journal of Healthcare Analytics Vol. 4 No. 2 (2025): November 2025
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v4i2.15750

Abstract

Infertility affects 8–12% of couples, with varicocele being the most common correctable male factor. Microsurgical subinguinal varicocelectomy offers better reproductive results than conventional or laparoscopic techniques. To compare fertility outcomes and recurrence rates between microsurgical and conventional varicocelectomy (2020–2025). A systematic review of 371 articles identified 9 eligible studies assessing semen quality, pregnancy rate, hydrocele, and recurrence. Microsurgical varicocelectomy showed greater improvements in semen parameters and natural pregnancy rates, along with lower hydrocele and recurrence. Sperm count increased by 7.7 ± 4.5 million/mL. Microsurgical subinguinal varicocelectomy is safer and more effective, and remains the preferred approach for varicocele management in infertile men.