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The Relationship Between Age And Gender And The Time To Achieve Euthyroid Condition In Graves' Disease Patients Who Receive Antithyroid Drug Therapy Miftah, Nanang; Mohtar, Ladika Avicena Dzikaf Masyahiro; Nur'Amin, Hendra Wana; Liani, Fauzia Noor; Yasmina, Alfi
Eduvest - Journal of Universal Studies Vol. 5 No. 3 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i3.1813

Abstract

Graves' disease is an autoimmune disease that most common cause of hyperthyroidism which is characterized by diffuse thyroid disease, thyrotoxicosis, and can be accompanied by orbitopathy and dermopathy. Age and gender are factors that are thought to influence the time it takes for GD patients to reach a euthyroid state who receive antithyroid drug therapy. The aim of this study was to determine the relationship between age and gender on the time to achieve euthyroidism in GD patients who received anti- thyroid drug therapy. This analytical observational study is a cohort study conducted using the Borneo Wetland Study on Thyroid 2 (BEST-T 2) Endocrine Polyclinic, Ulin Hospital Banjarmasin database. Data on 68 GD patients were taken using the total sampling method. Data were analyzed using the Cox Regression test with SPSS version 26 with a confidence level of 95%. Survival data will be displayed using the Kaplan Meier curve. This study showed that there was no relationship with age (p=0.064), but showed there was a relationship with gender (p=0.044) on the time to achieve euthyroidism in Graves' disease patients.
Manfaat Klinis Insulin Glargine U300 - Insulin Basal Generasi Kedua: Analisis Miftah, Nanang
Cermin Dunia Kedokteran Vol 51 No 11 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i11.1363

Abstract

Untreated diabetes can lead to complications and increase the risk of death. Many patients with type 2 diabetes will require injectable medication within 5-10 years after diagnosis, following the failure of two or three oral antidiabetic therapies. Adding basal insulin can be well tolerated, more effective with lower risks of hypoglycemia and weight gain compared to other insulin regimens, but it carries a risk of hypoglycemia. Insulin glargine U300, with its special formulation, reduces the risk of hypoglycemia in diabetic patients.