Article Per Year (5 Year)
p-Index From 2020 - 2025
0.408
P-Index
This Author published in this journals
All Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH)
arniwati mat daud, Noor
Unknown Affiliation
Computer Science & IT Decision Sciences, Operations Research & Management Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Teratogenic Tinospora Cordifolia And Carica Papaya On White Mouse Fetuses (Mus Musculus) ardiyantoro, Bagas; arniwati mat daud, Noor
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4241

Abstract

Tinospora cordifolia and Carica papaya in the production of traditional herbal medicines, specifically in formulations known as tinospora cordifolia and Carica papaya herbal mixtures. Extracts from Tinospora cordifolia stems and Carica papaya contain bioactive flavonoid antioxidants, which can inhibit phosphodiesterase enzymes that hydrolyze cAMP. Elevated cAMP concentrations can impede growth acceleration. This research aims to assess the teratogenic effects on the fetuses of white mice after administering tinospora cordifolia and carica papaya extracts. The study involved 25 Mus musculus divided into five groups. The first group, serving as the negative control, received 0.5% Na CMC, while the second group, serving as the positive control, was injected with intravenous Cyclophosphamide at 50 mg/kg. The other groups were administered various doses: ET Dose 1120, ECP Dose 1120, Dose 1 ETCP 2:1, Dose 2 ETCP 1:2, and Dose 3 ETCP 1:1. The extracts were given during the organogenesis period, and on the 18th day, the mice underwent laparotomy to collect the fetuses. The research findings indicate that tinospora cordifolia and carica papaya extracts can cause teratogenic effects, particularly at Dose 3 ETCP 1:1.
Teratogenic Tinospora Cordifolia And Carica Papaya On White Mouse Fetuses (Mus Musculus) ardiyantoro, Bagas; arniwati mat daud, Noor
Proceeding of the International Conference Health, Science And Technology (ICOHETECH) 2024: Proceeding of the 5th International Conference Health, Science And Technology (ICOHETECH)
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/icohetech.v5i1.4241

Abstract

Tinospora cordifolia and Carica papaya in the production of traditional herbal medicines, specifically in formulations known as tinospora cordifolia and Carica papaya herbal mixtures. Extracts from Tinospora cordifolia stems and Carica papaya contain bioactive flavonoid antioxidants, which can inhibit phosphodiesterase enzymes that hydrolyze cAMP. Elevated cAMP concentrations can impede growth acceleration. This research aims to assess the teratogenic effects on the fetuses of white mice after administering tinospora cordifolia and carica papaya extracts. The study involved 25 Mus musculus divided into five groups. The first group, serving as the negative control, received 0.5% Na CMC, while the second group, serving as the positive control, was injected with intravenous Cyclophosphamide at 50 mg/kg. The other groups were administered various doses: ET Dose 1120, ECP Dose 1120, Dose 1 ETCP 2:1, Dose 2 ETCP 1:2, and Dose 3 ETCP 1:1. The extracts were given during the organogenesis period, and on the 18th day, the mice underwent laparotomy to collect the fetuses. The research findings indicate that tinospora cordifolia and carica papaya extracts can cause teratogenic effects, particularly at Dose 3 ETCP 1:1.
Co-Authors Bagas Ardiyantoro