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All Journal Journal of Comprehensive Science Enrichment: Journal of Multidisciplinary Research and Development
Natih, Made Agus Raditya
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Humanities Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Engineering Health Professions Languange, Linguistic, Communication & Media Library & Information Science Social Sciences

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Perbandingan Tangential Flow Filtration Dan Dead-End Filtration: Potensi Dan Aplikasi Dalam Nanomedicine Natih, Made Agus Raditya; Sukrawati, Linda; Paramitha, Paramitha; Vedani, Trisalya
Journal of Comprehensive Science Vol. 4 No. 5 (2025): Journal of Comprehensive Science (JCS)
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v4i5.3165

Abstract

Sterilisasi merupakan proses penting dalam menjamin keamanan dan kualitas produk di bidang farmasi dan pangan, dengan tujuan utama menghilangkan seluruh mikroorganisme dari suatu material. Salah satu metode yang banyak digunakan adalah filtrasi membran, yang terbagi menjadi dua pendekatan utama: Tangential Flow Filtration (TFF) dan Dead-End Filtration (DEF). Artikel ini menyajikan tinjauan literatur terhadap kedua metode tersebut berdasarkan berbagai sumber ilmiah dari database terpercaya. TFF dinilai lebih unggul dalam efisiensi dan keberlanjutan proses filtrasi karena aliran sejajarnya mampu mengurangi akumulasi padatan di permukaan membran. Hal ini menjadikan TFF sangat cocok untuk aplikasi berteknologi tinggi seperti pemurnian nanopartikel dan pengolahan produk pangan cair, misalnya jus buah tropis. Sebaliknya, DEF merupakan metode yang lebih sederhana dan ekonomis, namun membutuhkan perawatan dan penggantian filter secara berkala karena akumulasi padatan lebih cepat terjadi. Studi ini menekankan bahwa pemilihan metode filtrasi harus disesuaikan dengan karakteristik aplikasi, serta mempertimbangkan parameter operasional seperti tekanan, suhu, dan ukuran pori membran. Dari 100 artikel yang ditelusuri secara daring, sebanyak 30 artikel terpilih dianalisis secara kualitatif untuk mendukung pembahasan dalam tinjauan ini.
Potential Therapeutic Compounds for Neurological Diseases in Lavender Oil Extract (Lavandula Angustifolia) Natih, Made Agus Raditya
Enrichment: Journal of Multidisciplinary Research and Development Vol. 3 No. 2 (2025): Enrichment: Journal of Multidisciplinary Research and Development
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/enrichment.v3i2.358

Abstract

Lavender oil (Lavandula angustifolia) is widely known for its soothing aromatherapy effects and diverse therapeutic benefits. The plant is rich in bioactive compounds—terpenes (linalool, limonene, triterpenes), linalyl acetate, alcohols, ketones, polyphenols, coumarin, sineol, and flavonoids—with linalool and linalyl acetate as the main components. The flower part is chosen for oil extraction because it contains the highest concentration of compounds. This literature review aims to identify the potential of lavender oil in the treatment of neurological diseases. Sources were taken from international journals indexed by Google Scholar, PubMed, and Scopus using the Publish or Perish program in the range of 2019–2024 with the keywords "aromatherapy" AND "neurological disorders" AND "lavender" AND "essential oils" AND "neurological diseases". Of the 78 articles identified, 47 were further reviewed and 12 met the inclusion criteria; The data is analyzed descriptively. Results showed that lavender oil has anxiolytic and antidepressant effects through modulation of GABA-A, SERT, and NMDA receptors; anti-inflammatory effect and regulation of glutamate receptors as well as inhibition of calcium channels; as well as anti-epileptic mechanisms through increased GABA inhibition, potassium current, and decreased sodium flow. Effectiveness has been reported in conditions such as anxiety, major depression, epilepsy, migraines, and Alzheimer's. In conclusion, lavender aromatherapy is effective for the therapy of neurological disorders thanks to the content of linalool and linalyl acetate. The implications of this study are as a reference for the development of methods and further research on the clinical potential of lavender oil in the treatment of neurological diseases.
Co-Authors Paramitha Paramitha Sukrawati, Linda Vedani, Trisalya