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All Journal Ensiklopedia of Journal Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)
Rizki, Famella Yustika
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Arts Humanities Computer Science & IT Dentistry Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Case Report: 60-Year-Old Female with Ischemic Stroke, Type 2 Diabetes Mellitus, and Hypertension Husnawati, Husnawati; Andriani, Dita Maulida; Rizki, Famella Yustika; Wanty, Fitri Prima; Sinaga, Giacinta Gracesandy; Rahmi, Helvy; Anggraini, Laurentin Leni; Khairani, Putri; Sakinah, Rezkila; Rasihen, Sri Lidya; Wahyudi, Wahyudi; Sinulinga, Yori Yunita
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1564

Abstract

Background: Ischemic stroke remains a leading cause of death and disability worldwide, with increasing incidence each year. Patients with comorbidities, such as Type 2 diabetes mellitus (DM), pose additional treatment challenges due to a higher risk of drug-related problems (DRPs), particularly drug interactions. Objective: This study aims to describe pharmaceutical care in female patients diagnosed with ischemic stroke and Type 2 DM, with a focus on identifying and evaluating DRPs. Method: A descriptive case study was conducted. Data were collected through medical records and patient monitoring, focusing on the identification and analysis of potential DRPs in the context of pharmaceutical care. Results: The study found drug interactions as the most prominent DRP. An interaction between potassium slow-release (KSR) and candesartan was identified as requiring monitoring. Additionally, moderate interactions were found between atorvastatin and clopidogrel, as well as atorvastatin and amlodipine. These interactions have the potential to influence therapeutic outcomes. Conclusion: The prescribed medication regimen was generally appropriate for the patient's condition. Nevertheless, the presence of DRPs highlights the importance of regular monitoring and dose adjustments. Optimizing pharmaceutical care through early detection and management of DRPs is essential to ensure treatment safety and effectiveness in patients with complex conditions.
ANALISIS TERAPI METFORMIN DENGAN GLIMEPIRID PADA PASIEN DIABETES MELITUS TIPE II Hasti, Syilfia; Rizki, Famella Yustika; Sinata, Novia; Satiya, Selin Faysa
Ensiklopedia of Journal Vol 7, No 4 (2025): Vol. 7 No. 4 Edisi 2 Juli 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i4.3280

Abstract

Abstract: Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Hyperglycemia is a medical condition in the form of an increase in blood glucose levels that exceeds normal. Based on the cause, DM can be classified into 4 groups, namely type I DM, type II DM, gestational DM and other types of DM. The purpose of this study was to determine the comparison of the decrease in blood glucose levels when type 2 DM patients were hospitalized with Metformin and Glimepirid. This research is an observational study with the type of analytic descriptive study. The sample in the study amounted to 103 patients, the sample was taken using a purposive sampling technique and the instrument used was medical record data of type 2 diabetes mellitus patients. Data analysis used the Mann Whitney test and the Wilcoxon test. The results showed that there was no significant difference (p>0.05) between generic metformin monotherapy and generic glimepiride monotherapy in lowering transient blood glucose levels.Keywords: Diabetes Melitus Type II, Metformin, Glimepirid, Current Blood Glucose.
Co-Authors Andriani, Dita Maulida Anggraini, Laurentin Leni Husnawati Husnawati Khairani, Putri Rahmi, Helvy Rasihen, Sri Lidya Sakinah, Rezkila Satiya, Selin Faysa Sinaga, Giacinta Gracesandy Sinata, Novia Sinulinga, Yori Yunita Syilfia Hasti Wahyudi Wahyudi Wanty, Fitri Prima