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Sinjari, Bruna
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Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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The Role of Mesenchymal Stem Cells in Stroke Recovery: A Regenerative Medicine Approach with Medical Rehabilitation Vinski, Deby Susanti Pada; Sinjari, Bruna; Ernandini, Endang; Vinski, Natasha Cinta; Nugroho, Andi Kurniawan
Journal of World Science Vol. 4 No. 4 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i4.1404

Abstract

This study examines the role of mesenchymal stem cells (MSCs) in stroke recovery, exploring their regenerative properties and potential to enhance rehabilitation outcomes. Stroke remains a leading cause of long-term disability, with limited treatment options for functional recovery. This research investigates how MSC therapy, combined with conventional rehabilitation methods, can improve motor and cognitive function in stroke patients. Using case studies and patient care records, the study analyzes the effectiveness of MSC therapy in promoting neural repair, reducing disability levels, and improving overall quality of life. The findings suggest that MSC therapy significantly enhances functional recovery when integrated with rehabilitation, particularly when cerebrospinal fluid treatment is used before MSC administration. Imaging and biomarker analyses support these results, showing improvements in neurogenesis, synaptic plasticity, and reduced neuroinflammation. This research highlights the synergistic effects of MSC therapy and rehabilitation, presenting a promising approach to stroke recovery. The study also emphasizes the need for further research to optimize MSC-based treatments, refine delivery methods, and evaluate long-term safety and effectiveness. The implications of this study contribute to the development of integrated therapeutic strategies for stroke patients, offering a more holistic approach to recovery.
Co-Authors Andi Kurniawan Nugroho Ernandini, Endang Vinski, Deby Susanti Pada Vinski, Natasha Cinta