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All Journal Biology, Medicine, & Natural Product Chemistry Jurnal Sylva Lestari
Limbong, Zest Lively
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Energy Environmental Science Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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In Vivo Evaluation of Antidepressant Potential of Temulawak (Curcuma xanthorriza Robb.) Ethanol Extract in Mus musculus Virgilius, Raja David; Limbong, Zest Lively; Ginting, Jericho L.
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.239-242

Abstract

Temulawak (Curcuma xanthorriza Roxb.) is a medicinal plant from the Zingiberceae family widely used in Indonesia for its various bioactives, including antiviral, antibacterial, and hepatoprotective properties. This research aims to evaluate the antidepressant potential of Curcuma xanthorriza ethanol extract in Mus musculus through in vivo testing. The extraction used the maceration method with 96% ethanol as a solvent, yielding 5.2504% extract. The primary bioactive compounds identified in the extract were terpenoids and curcuminoids, which are known for their neuroprotective and antidepressant effects. The antidepressant activity was assessed using the tail-suspension test (TST) and forced-swimming test (FST), with immobility time as the main parameter. Amitriptyline, a standard antidepressant, was used as a positive control, while sodium carboxymethylcellulose served as a negative control. The results showed that increasing doses of Curcuma xanthorriza extract significantly reduced immobility time, indicating an antidepressant-like effect. Statistical analysis revealed that the immobility time in mice treated with a 650 mg/Kg BW dose of Curcuma xanthorriza extract was not significantly different from the amitriptyline group, suggesting comparable efficacy. These findings highlight the potential of Curcuma xanthorriza ethanol extract as a natural antidepressant, warranting further investigation into its mechanisms and clinical applications.
Time Consumption and Productivity of Motorbike Timber Extraction in Private Forests Budiaman, Ahmad; Hardjanto; Limbong, Zest Lively
Jurnal Sylva Lestari Vol. 12 No. 1 (2024): January
Publisher : Department of Forestry, Faculty of Agriculture, University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jsl.v12i1.815

Abstract

Timber extraction in private forests in Indonesia is carried out using appropriate technology. Motorbike extraction is one of the means of timber extraction widely used in private forests in Indonesia. This research aimed to analyze the working time and productivity of timber extraction using motorbikes in private forests. The research was conducted in a private forest in Probolinggo, East Java. The terrain conditions at the study site were partly flat and partly rather steep. The study site can only be accessed through a footpath that is 2 m wide. Observations were made on three motorbikes. The number of trips for each motorbike was 11 trips. The skidding distance was 300 m. Data on timber extraction work time were obtained through video analysis. Production data on timber extraction were obtained through direct measurements in the field. The research showed that the work time spent to transport timber from private forests using motorbikes was 18.18 minutes per trip. The loaded travel spent the highest working time, followed by the empty travel, logs stacking, unloading, and traveling to logs. The efficiency of timber extraction using motorbikes in private forests was 82.11%. The productivity of timber extraction was 0.61 m3/hour or 0.002 m3/hour.m. Keywords: appropriate technology, motorbike, private forests, timber extraction, working time
Co-Authors Ahmad Budiaman Ginting, Jericho L. Hardjanto Virgilius, Raja David