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All Journal Heart Science Journal
Saputri, Vemmy Lian
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Health Professions Immunology & microbiology Medicine & Pharmacology

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Case series analysis: Atrial fibrillation ablation with normal vs. left atrium enlargement Baskoro, Shalahuddin Suryo; Saerang, Gebryel Dennis; Saputri, Vemmy Lian; Rizal, Ardian; Wikananda, Adhika Prastya; Waranugraha, Yoga
Heart Science Journal Vol. 6 No. 2 (2025): The Complexity in the Management of Heart Rhythm Disorder
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.02.15

Abstract

Background: Atrial fibrillation (AF) is one of the most common cardiac arrhythmias, and its incidence is gradually increasing worldwide. It can develop such life-threatening conditions as heart failure, myocardial infarction, and thromboembolism. Catheter ablation, as a minimally invasive procedure to eliminate AF triggers, demonstrates different levels of success, particularly in relation to the size of the left atrium (LA). Even though left atrium enlargement (LAE) associates with worse ablation outcomes, its mechanisms are poorly understood. Case Illustration: This case report investigated the treatment results in AF ablation cases with normal LA size and LAE. This case report described two paroxysmal AF patients who underwent catheter ablation. The patient of the first case is a 45-year-old male with normal LA Size, while the second case is a 55-year-old male with LAE. Both of these patients underwent pulmonary vein isolation (PVI) using a 3D mapping system. Sinus rhythm was gained in both patients before the discharge and both performed the ablation successfully. Conclusion: Left Atrial Enlargement (LAE) exposed patient to more difficult procedures and greater risk of recurrence. LA size is one of the predictor of long term outcome in AF ablation patients, but with proper management, the prognosis might still be favourable. More studies need to determine how to manage AF ablation in patients with high-risk characteristics 
Hype or hope: The role of alcohol septal ablation in improving outcomes for young patients with obstructive hypertrophic cardiomyopathy: A case series Saputri, Vemmy Lian; Rizal, Ardian; Rahimah, Anna Fuji; Karolina, Wella; Yogibuana, Valerinna; Prasetya, Indra
Heart Science Journal Vol. 6 No. 3 (2025): Advancements in Cardiac Imaging : Unlocking New Perspectives on the Heart Visua
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.03.19

Abstract

Background: Hypertrophic cardiomyopathy (HCM) is a disease that has a poor prognosis and a higher likelihood of death in young people. Alcohol septal ablation (ASA) is a minimally invasive procedure that involves the injection of ethanol through a septal perforator to lead to infarction of the hypertrophied septum. This case series aims to present data on the beneficial effects of ASA in promoting hope for enhanced outcomes in young patients with HCM. Case: Patient 1: A 32-year-old male with HCM has been suffering from chest discomfort and atrial fibrillation since 2020. Echocardiography detected an increased obstruction in the left ventricular outflow tract (LVOT), resulting in a gradient of 104 mmHg. The patient underwent ASA to decrease the gradient to 37 mmHg, reducing hospitalizations throughout a 12-month follow-up period. Patient 2: A 27-year-old female diagnosed with HCM has been frequently suffering episodes of near syncope and shortness of breath with light activity over the past 6 months. The echocardiography findings showed a significant increase in the resting gradient in the LVOT. Following ASA, the resting gradient decreased to 54 mmHg during a 3-month follow-up. The patient did not suffer further near syncope events, and her NYHA functional class improved throughout a 9-month follow-up period. Conclusion: The effectiveness of ASA as a treatment option is hope for young patients with obstructive HCM, which is demonstrated in this case series, leading to relieving symptoms, reduced repeated hospitalization, and improved functional capacity.
Co-Authors Baskoro, Shalahuddin Suryo Indra Prasetya Karolina, Wella Rahimah, Anna Fuji Rizal, Ardian Saerang, Gebryel Dennis Wikananda, Adhika Prastya Yoga Waranugraha Yogibuana, Valerinna