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All Journal International Journal of Applied and Scientific Research (IJASR)
Ohiwerei Wisdom O
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Impact of Tigernuts on Blood Glucose and Insulin Levels in Normal Weight Male Humans Edokpolor N, Igbinovia; Ohiwerei Wisdom O; Blackie Okosun H; Edebiri Ogbemudia E; Otaye Micheal O; Ohiwerei Faith O
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Abstract

Tigernuts contain bioactive compounds such as sterols, alkaloids, tannins, saponins, resins, and vitamins E and C. This study examined their effects on blood glucose and insulin levels in normal-weight male subjects under resting conditions. Methods: Forty non-habitual tigernut chewers, aged 18–28 years, participated. After recording anthropometric data, subjects rested for 90 minutes. Blood glucose levels were measured using the enzymatic method of Barham and Trinder with a glucometer. Insulin levels were assessed using the ELISA Teco kit following Tiez and Andresen's method. On a separate day, the same subjects consumed 5g of tigernuts as a bolus, followed by 50ml of water. After another 90-minute rest, blood glucose and insulin levels were reassessed. Statistical analysis was conducted using GraphPad Prism Version 8.1. Results: Tigernut consumption led to a slight reduction in blood glucose levels (92.66 ± 2.156 to 89.61 ± 1.907 mg/dl), though not statistically significant. However, insulin levels showed a significant decrease (P<0.05, 4.220 ± 0.297 to 1.705 ± 0.061 µg/ml). Conclusion: Tigernuts demonstrated both blood glucose and insulin-lowering effects in normal-weight male subjects
Effects of Tigernuts on Blood Urea, Uric Acid and Creatinine Levels in the Normal Weight Male Humans Igbinovia Edokpolor N; Ohiwerei Wisdom O; Festus Oloruntoba O; Ohiwerei Faith O; Onokevbagbe Elisha O
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Natural antioxidants are gaining significant attention from nutritionists, food manufacturers, medical professionals, and consumers due to their numerous health benefits. This study explored the potential effects of tigernuts on blood urea, uric acid, and creatinine levels in normal-weight male subjects under resting conditions, as well as the possible mechanisms involved. Methods: A total of forty (40) non-habitual tigernut chewers, aged 18–28 years, participated in the study. After recording the anthropometric data of the control group, the subjects rested for 1 hour and 30 minutes. Urea levels were measured colorimetrically using the Urease-Berthelot’s Method, where urea in plasma was hydrolyzed to ammonia in the presence of urease, and the resulting ammonia was detected photometrically through Berthelot’s reaction. Uric acid was determined using an enzymatic colorimetric method, while creatinine was assessed using the Modified Jaffe’s Method, in which creatinine in the sample reacted with picrate in an alkaline medium to form a colored complex, measured within a short period to minimize interference.On a separate day, 5g of tigernuts were given to the same subjects—who had previously served as controls—to be chewed as a bolus. Findings indicated that tigernuts significantly reduced (P < 0.05) blood urea levels post-consumption (from 16.32 ± 0.759 to 11.76 ± 1.325 mg/dl). However, uric acid levels significantly increased (P < 0.05) following ingestion (from 2.438 ± 0.439 to 4.851 ± 0.393 mg/dl). Blood creatinine levels decreased from 1.778 ± 0.093 to 1.617 ± 0.089 g/dl, though this reduction was not statistically significant. This study suggests that tigernuts have beneficial effects on renal urea and creatinine levels, supporting their consumption for maintaining kidney health
Co-Authors Blackie Okosun H Edebiri Ogbemudia E Edokpolor N, Igbinovia Festus Oloruntoba O Igbinovia Edokpolor N Ohiwerei Faith O Onokevbagbe Elisha O Otaye Micheal O