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All Journal International Journal of Applied and Scientific Research (IJASR)
Festus Oloruntoba O
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Effects of Tigernuts on Blood Urea, Uric Acid and Creatinine Levels in the Normal Weight Male Humans Igbinovia Edokpolor N; Ohiwerei Wisdom O; Festus Oloruntoba O; Ohiwerei Faith O; Onokevbagbe Elisha O
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Abstract

Natural antioxidants are gaining significant attention from nutritionists, food manufacturers, medical professionals, and consumers due to their numerous health benefits. This study explored the potential effects of tigernuts on blood urea, uric acid, and creatinine levels in normal-weight male subjects under resting conditions, as well as the possible mechanisms involved. Methods: A total of forty (40) non-habitual tigernut chewers, aged 18–28 years, participated in the study. After recording the anthropometric data of the control group, the subjects rested for 1 hour and 30 minutes. Urea levels were measured colorimetrically using the Urease-Berthelot’s Method, where urea in plasma was hydrolyzed to ammonia in the presence of urease, and the resulting ammonia was detected photometrically through Berthelot’s reaction. Uric acid was determined using an enzymatic colorimetric method, while creatinine was assessed using the Modified Jaffe’s Method, in which creatinine in the sample reacted with picrate in an alkaline medium to form a colored complex, measured within a short period to minimize interference.On a separate day, 5g of tigernuts were given to the same subjects—who had previously served as controls—to be chewed as a bolus. Findings indicated that tigernuts significantly reduced (P < 0.05) blood urea levels post-consumption (from 16.32 ± 0.759 to 11.76 ± 1.325 mg/dl). However, uric acid levels significantly increased (P < 0.05) following ingestion (from 2.438 ± 0.439 to 4.851 ± 0.393 mg/dl). Blood creatinine levels decreased from 1.778 ± 0.093 to 1.617 ± 0.089 g/dl, though this reduction was not statistically significant. This study suggests that tigernuts have beneficial effects on renal urea and creatinine levels, supporting their consumption for maintaining kidney health
Influence of Tigernuts on the Antioxidant Vitamins Levels in Normal Weight Male Human Subjects Edokpolor N, Igbinovia; Wisdom O, Ohiwerei; Festus Oloruntoba O; Onokevbagbe Elisha I; Adisa W A
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

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Tubers have been recognized as a valuable source of essential macro- and micronutrients vital for overall health. Among these, tigernut has been gaining popularity due to its rich composition. This tuber contains bioactive compounds such as sterols, alkaloids, tannins, saponins, resins, and vitamins E and C. Natural antioxidants have attracted significant attention from nutritionists, food manufacturers, medical professionals, and consumers due to their numerous health benefits. This study aimed to examine the effect of tigernuts on human vitamin A, C, and E levels in normal-weight male subjects under resting conditions, as well as to explore potential mechanisms of action. Methods: The study involved forty (40) male participants who were non-habitual tigernut consumers, aged 18–28 years. Anthropometric data were recorded for control subjects, who then rested for 1 hour and 30 minutes. Serum vitamin C levels were analyzed using a spectrophotometric method, with ascorbic acid showing maximum absorption at 478.5 nm in methanolOn a separate day, each participant was given 5g of tigernut to chew as a bolus, with the same subjects serving as both control and test participants.The findings revealed that tigernut consumption significantly increased (P < 0.05) vitamin E levels from 0.09573 ± 0.021 to 0.8430 ± 0.057 mg/%. In contrast, vitamin A levels significantly decreased (P < 0.05) from 291.8 ± 29.50 to 97.89 ± 32.36 mg/%. Vitamin C levels also declined post-consumption, from 1.586 ± 0.201 to 1.188 ± 0.080 mg/%, though this decrease was not statistically significant.The results suggest that tigernut consumption enhances vitamin E levels while reducing both vitamin A and C levels in normal-weight male subjects
Co-Authors Adisa W A Edokpolor N, Igbinovia Igbinovia Edokpolor N Ohiwerei Faith O Ohiwerei Wisdom O Onokevbagbe Elisha I Onokevbagbe Elisha O Wisdom O, Ohiwerei