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All Journal Pharmacology and Clinical Pharmacy Research
Nuryady, Moh M.
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Medicine & Pharmacology

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The Potency of Polymeric Nanoparticles as New Drug Delivery System: A Narrative Review Ariesaka, Kiky M.; Hidayati, Zulfa; Nurhayati, Siti; Dewi, Ni L.M.N.; Nuryady, Moh M.
Pharmacology and Clinical Pharmacy Research Vol 10, No 1 (2025)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v10i1.56782

Abstract

Polymeric nanoparticles are particles ranging from 1 to 1,000 nm that can be loaded with active compounds. Polymeric nanoparticles can be classified based on their morphological structure into nanocapsules and nanospheres. In addition, polymeric nanoparticles can also be classified based on the compound’s origin into natural and synthetic polymer. The nanoparticle production method is adjusted based on the type of drug that will be loaded. The methods commonly used for the production of polymeric nanoparticles are solvent evaporation, solvent emulsification/ diffusion, nanoprecipitation, emulsification/ reverse-salting out, and nanoprecipitation. This review also provides several examples of clinical applications of nanoparticles in the formulation of several drugs/bioactives including hyperforin, curcumin, and amphotericin B.
Co-Authors Ariesaka, Kiky M. Dewi, Ni L.M.N. Hidayati, Zulfa Siti Nurhayati