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All Journal Nusantara Hasana Journal International Journal Of Public Health
Cindy Octavia
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Agriculture, Biological Sciences & Forestry Humanities Economics, Econometrics & Finance Education Health Professions Nursing Public Health

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AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN GAHARU ( Aquilaria malaccensis Lamk ) PADA MENCIT PUTIH JANTAN ( Mus Musculus ) Delladari Mayefis; Cindy Octavia; Sri Hainil; Rury Trisa Utami; Desy Maniarti Gusmali; Hesti Marliza; Nurliyasman, Nurliyasman
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1413

Abstract

Inflammation is a complex response that occurs in blood vessel tissue due to external or internal stimuli. One plant that is known to have anti-inflammatory properties is agarwood leaves (Aquilaria malaccensis Lam). This study aims to evaluate the effect of ethanol extract from gaharu leaves on anti-inflammatory activity in male white mice (Mus musculus) and to determine the most effective dose. The experimental animals were divided into five groups, including a control group that received Na CMC and diclofenac sodium. Inflammation induction was carried out through injection of egg white solution, and measurements were carried out periodically for six hours. The analysis results showed that a dose of 300 mg/KgBW of agarwood leaf extract provided the most significant anti-inflammatory effect compared to lower doses. 100 mg/kgBB and 200 mg/kgBB
Integrating Infant Massage and Aromatherapy as a Complementary Non-Pharmacological Intervention in Supporting Infant Growth and Development Darah Ifalahma; Totok Wahyudi; Cindy Octavia; Risma Nurul Istiqomah
International Journal of Public Health Vol. 2 No. 4 (2025): December : International Journal of Public Health
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijph.v2i4.560

Abstract

Early childhood is a critical period for growth and development, characterized by rapid changes in neurological, motor, sensory, and emotional systems. Stimulation during this stage plays a vital role, and non-pharmacological interventions such as massage and aromatherapy may enhance developmental outcomes. This quasi-experimental study employed a pretest–posttest control group design to evaluate the effectiveness of infant massage combined with aromatherapy. Twenty infants aged 3–12 months who met inclusion and exclusion criteria were recruited and assigned to either a control group (infant massage only) or an intervention group (infant massage with aromatherapy). Growth parameters (weight, length, head circumference) and developmental outcomes were measured using the Developmental Pre-Screening Questionnaire, covering gross motor, fine motor, language, and personal-social domains. Infants in the intervention group demonstrated significantly greater improvements in body weight, body length, head circumference, and developmental scores compared to the control group. These findings indicate that the addition of aromatherapy to infant massage provides measurable benefits for both physical growth and developmental progress. Combined infant massage and aromatherapy represent effective non-pharmacological strategies for early stimulation, supporting optimal growth and developmental trajectories in infants.
Co-Authors Darah Ifalahma Delladari Mayefis Desy Maniarti Gusmali Hesti Marliza Nurliyasman Nurliyasman Risma Nurul Istiqomah Rury Trisa Utami Sri Hainil Totok Wahyudi