Sofro, Muchlis AU
Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Canavalia ensiformis Protein Extract Effect Toward Serum Lipid Profile of Hypercholesterolemic Sprague Dawley Rat Naufalina, Mira Dian; Sofro, Muchlis AU; Anjani, Gemala
KEMAS: Jurnal Kesehatan Masyarakat Vol 14, No 1 (2018)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v14i1.10678

Abstract

Riskesdas 2013 showed the prevalence of abnormal total cholesterol levels in Indonesia is 35.9%, low HDL cholesterol is 22.9%, high LDL cholesterol is 15.9%, and high triglyceride is 11.9%. This study aimed to prove the effect of jack bean protein extract toward serum lipid profile of a hypercholesterolemic rat. This was a true experimental study conducted in September 2016 with post-only control group design. Twenty four male Sprague Dawley rats were randomly classified into 4 different groups; control negative group (C-), control positive group (C+), first experimental group (X1) which was given jack bean extract 4g/200g of body weight of the rat per day, and second experimental group (X2) which was given jack bean extracts 6g/200g of body weight of the rat per day. Treatment for 2 weeks showed a significant effect. Total cholesterol, LDL cholesterol, and triglycerides levels of groups with protein jack bean extract administration were lower than the positive control group (p <0.05). Increasing doses of jack bean extracts was linear with serum lipid profile improvement of Sprague Dawley Rat. These result indicated the positive effect of jack bean protein extract toward serum lipid profile of hypercholesterolemic Sprague Dawley Rat.
Risk Factors of Gonorrhoea Among Female Indirect Sex Workers Nugrahaeni, Anita; Sofro, Muchlis AU; Shaluhiyah, Zahroh; Suryosaputro, Antono; Widjanarko, Bagoes
Journal of Epidemiology and Public Health Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (526.182 KB)

Abstract

Background: Gonorrhoea is one of sexually transmitted infections (STI) with high incidence, besides chlamydia, syphilis, and trichomoniasis. STIs are spread predominantly by sexual context including vaginal, anal, and oral. STIs have a profound impact on sexual and reproductive health worldwide. STIs can increase the risk of HIV acquisition three fold or more. This study aimed to determine the risk factors of gonorrhoea among female indirect sex workers.Subjects and Method: This was a case control study carried out in Wonosobo district, Central Java, from April to May 2017. A sample of 84 female indirect sex workers were selected for this study consisting of 42 cases of gonorrhea and 42 control. The dependent variable was gonorrhoea. The independent variables were sex combination and condom use. Data on gonorrhoea was collected from STI clinic. The other data were collected by questionnaire. The data were analyzed using logistic regression.Results: The risk of gonorrhoea among female indirect sex workers increased with sex combination practice (OR=3.17; p=0.027; 95% CI= 1.14 to 8.82) and absence of condom use (OR= 8.04; 95% CI= 2.30 to 28.12; p=0.001).Conclusion: The risk of gonorrhoea among female indirect sex workers increases with sex combination practice and absence of condom use.Keywords : gonorrhoea, sex combination, condom use, female, indirect sex workersCorrespondence: Anita Nugrahaeni. Masters Program in Epidemiology, Diponegoro University, Jl. Imam Bardjo SH No. 5, Semarang, Central Java. Email: nitaozora@gmail.com. Mobile: 081335980666.Journal of Epidemiology and Public Health (2017), 2(3): 216-224https://doi.org/10.26911/jepublichealth.2017.02.03.03