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All Journal Sehat Rakyat: Jurnal Kesehatan Masyarakat Hang Tuah Medical Journal
MINNALIA SOAKAKONE
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Analisis Pemberian Ekstrak Rumput Kebar (Biophytum Petersianum Klotzsch) Terhadap Kadar MDA Mencit Model Diabetes Melitus : Analisis Pengaruh Pemberian EKstrak Rumput Kebar (Biophytum petersianum Klotzsch) terhadap kadar MDA mencit model diabetes melitus DJURUMANA, YOHANA; MINNALIA SOAKAKONE; YOWAN EMBUAI
Hang Tuah Medical Journal Vol 22 No 2 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v22i2.482

Abstract

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia and abnormalities in the metabolism of carbohydrates, fats, and proteins. The mechanisms of diabetes mellitus can affect infertility starting with an increase in free radicals due to hyperglycemic conditions, leading to glucose auto-oxidation, protein glycation, and activation of the polyol pathway metabolism, which further accelerates the formation of reactive oxygen species. Oxidative stress increases the amount of Reactive Oxygen Species (ROS), oxidizes unsaturated fatty acids in spermatozoa membranes, leading to a chain reaction in cell membranes and the formation of toxic lipid peroxides. Lipid peroxides generate aldehyde compounds due to the disruption of the fatty acid chain, such as Malondialdehyde (MDA). Malondialdehyde (MDA) is a marker of oxidative stress. This study aims to evaluate the effect of Kebar Grass extract on the level of MDA (malondialdehyde), which is one of the indicators of oxidative stress, in a diabetic mouse model. The mice in this study were divided into two groups: a diabetes control group and a treatment group receiving Kebar Grass extract. The results of the study indicate that the administration of Kebar Grass extract did not have a significant effect on the MDA levels in the diabetic mouse model. Although there was a trend of decreased MDA levels in the treatment group, the difference did not reach a statistically significant level. This research indicates that although Elephant Grass has the potential as a traditional remedy for diabetes management, its effect on reducing oxidative stress, measured by MDA levels, may not be very strong. Further research is needed to better understand the mechanisms of action of Elephant Grass in diabetes management and its impact on oxidative stress.
Determinasi Pendapatan, Ability to Pay, dan Jumlah Tanggungan terhadap Beban Biaya Kesehatan Peserta BPJS Mandiri: Studi pada Pedagang Pasar Passo Mersy Delty Kainama; Wuritimur, Pollan Versilia; Minnalia Soakakone
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 4 No. 4 (2025): November 2025
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v4i4.5678

Abstract

The National Health Insurance (JKN) is a program of the Indonesian government that, in principle, aims to provide health insurance for the Indonesian people. In Indonesia, people are at risk of catastrophic health payments, namely if health payments exceed 10% of household income. From a government perspective, government spending on health reaches 0.9% of GDP in Indonesia, much lower than Thailand (2.9%), China (2.7%), and Vietnam (2.6%). The purpose of this study was to determine the factors associated with the burden of health costs for families of BPJS Kesehatan Mandiri participants among traders in Passo Market. The research method in this study was quantitative with a cross-sectional approach. The results of the study indicate a relationship between income and the burden of health costs for independent BPJS participants with a P value of 0.044, with the average feeling of having a high cost burden being those with incomes <UMR. This study also shows a relationship between Ability to Pay (ATP) and the burden of health costs for independent BPJS participants with a P value of 0.047, with the average being unable to pay and feeling they have a high burden. This study also shows a relationship between the number of family members and the burden of health costs for independent BPJS participants, with the average number of family members being >5. Thus, Passo market traders, most of whom are independent BPJS participants, feel that they have a greater burden in financing their health.
Co-Authors Djurumana, Yohana Mersy Delty Kainama Wuritimur, Pollan Versilia YOWAN EMBUAI