Article Per Year (5 Year)
p-Index From 2020 - 2025
0.659
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Scientia Psychiatrica Neurona
Muhlisa, Safitri
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
FAKTOR-FAKTOR YANG MEMPENGARUHI LUARAN PADA PASIEN PERDARAHAN SUBARAKHNOID: PENELITIAN COHORT PROSPEKTIF 18 BULAN Muhlisa, Safitri; Ramadhoni, Pinto Desti; Junaidi, Achmad; Octavinawaty, Lenny; Adwirianny, Ashita Hulwah
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 2 (2024): Vol 40 No 2 (2024): Volume 40, No 2 - Maret 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i2.451

Abstract

Introduction: Subarachnoid hemorrhage (SAH) is an acute bleeding in the subarachnoid space. The mortality rate of SAH is quite high and survivors will experience limitations in activity daily living. Identification and factors that affect SAH are needed to improve patient outcomes. Aim: to identify the factors that affect the mortality of SAH Methods: This study was an observational study with a prospective cohort approach regarding the factors that affect the outcome of subarachnoid hemorrhagic patients in Dr. Mohammad Hoesin Hospital Palembang from January 2021 to July 2022. Results: From 62 subjects, the patients were 55.35 (SD ± 12.4) years old in average, most of them were female (67.7%). About 87.1% of patients had GCS> 8 (mean 11.68, SD ± 3.273). There were 82.3% of patients with mild-moderate NIHSS (mean 11.68; SD ± 3.273). The mortality rate was 37.1% (n = 23) with associated factors such as onset of admission (p = 0.044, GCS on admission (p= 0.003), severity of stroke (NIHSS) (p = 0.013), SAH severity (Hunt and Hess scale) (p=0.00), modified fisher scale (p=0.000), and coiling (p=0.001).The factor that most influenced the outcome was modified Fisher 3-4 (OR= 12,426, CI95% = 2,239 – 68,953) and non-coiling (OR: 12,2278, CI95% = 1,716 – 87,838). Discussion: There was a significant correlation between admission onset, GCS on admission, stroke severity (NIHSS score), modified Fisher scale, SAH severity (Hunt and Hess scale), and coiling, with the mortality of subarachnoid hemorrhage. Modified fisher scale and non-coiling were the most dominant factors that affected the mortality rate. Keywords: SAH, mortality, outcome
DIAGNOSTIC ACCURACY OF CLINICAL SCORING SYSTEMS (NSS, NDS, AND TCSS) COMPARED TO ELECTROPHYSIOLOGICAL TESTING IN DIABETIC NEUROPATHY AMONG T2DM PATIENTS Muhlisa, Safitri; Theresia Christin; Yulianto Kusnadi; Erial Bahar
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 3 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i3.689

Abstract

Diabetic neuropathy is one of the most common chronic complications in diabetes mellitus patients and can significantly impair quality of life. Early diagnosis is essential, but limited availability of diagnostic tools such as electrophysiological testing in many healthcare facilities calls for more practical and efficient alternatives. This study aimed to compare the diagnostic accuracy of three clinical scoring systems—NSS (Neuropathy Symptom Score), NDS (Neuropathy Disability Score), and TCSS (Toronto Clinical Scoring System)—in detecting diabetic neuropathy among Type 2 DM patients at Dr. Mohammad Hoesin Hospital, Palembang. A cross-sectional design was employed, and findings revealed that TCSS had the highest accuracy (90.3%) compared to NDS (85.5%) and NSS (85.4%). TCSS also demonstrated the best balance of sensitivity (95.4%) and specificity (77.8%). All three instruments can serve as effective early screening tools, especially in healthcare settings with limited access to electrophysiological diagnostic facilities.
The Role of Neurotransmitters in Relation to Psychiatric Conditions Throughout the COVID-19 Epidemic Muhlisa, Safitri
Scientia Psychiatrica Vol. 4 No. 4 (2023): Scientia Psychiatrica
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/scipsy.v4i3.116

Abstract

Various studies have reported the presence of psychiatric symptoms among individuals diagnosed with COVID-19, encompassing heightened stress levels, impaired cognitive function, depressive mood, anxiousness, post-traumatic stress disorder (PTSD), psychotic symptoms, and suicidal ideation. The objective of this review was to elucidate the involvement of neurotransmitters in psychiatric disorders following the COVID-19 pandemic. There are multiple variables that can influence the results of research studies examining the presence of symptoms or the initiation of psychiatric disorders in individuals diagnosed with COVID-19. Factors associated with mental health difficulties include direct involvement in the healthcare field, presence of a psychiatric disease within the family, limited social support, advanced age, solitary living arrangements, and the utilization of high dosages of steroids during the acute phase. Multiple types of neurotransmitters are involved in the modulation of stress levels inside the human body. The neurotransmitters implicated in this process include dopamine, serotonin, epinephrine and norepinephrine, acetylcholine, gamma-aminobutyric acid (GABA), and glutamate. In summary, cytokines have a pivotal role in modulating the hypothalamic-pituitary-adrenal (HPA) axis within the brain, hence potentially giving rise to psychiatric manifestations including impaired sleep, heightened stress, depressive affect, and several other psychological disturbances.
Co-Authors Achmad Junaidi, Achmad Adwirianny, Ashita Hulwah Erial Bahar Octavinawaty, Lenny Ramadhoni, Pinto Desti Theresia Christin Yulianto kusnadi