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All Journal Indonesian Journal of Pharmaceutical Science and Technology Innovative: Journal Of Social Science Research
Dewi, Ni Kadek Santi Maha
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Humanities Computer Science & IT Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Other

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Uniformity Test of Total Flavonoid Content in Antidiabetic Capsules from Ethanol Extract of Purple Sweet Potato Leaves (Ipomoea batatas L.) Suhendi, Jessica Rianty; Dewi, Ni Kadek Santi Maha; Warditiani, Ni Kadek; Arisanti, Cokorda Istri Sri; Wirasuta, I Made Agus Gelgel
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.53962

Abstract

The ethanol extract of purple sweet potato leaves (Ipomoea batatas L. or “IBL”) has antidiabetic activity, and the total flavonoid (KTF) is designated as the quality marker (Q-marker) in capsule manufacturing. This research aims to develop KTF As a Q-marker for OHT capsules from ethanol extract of IBL leaves as antidiabetic. KTF Q-marker determination involves: (1) Identification of the absorption peak of the quercetin-AlCl3 complex, (2) Method verification, and (3) Testing OHT capsule content uniformity. The Quersetin-AlCl3 complex provides a bathochromic shift in band I from 380 nm before being reacted towards 430 nm after complex formation. The method verification test resulted in a correlation coefficient of 0.998, intraday RSD of 0.76-2.00%, and interday RSD of 0.87-1.96%, and accuracy of return in the range 82.88-91.83%. The consistency test results of the capsule content of the four bets obtained a ratio of the content of 10 capsules of each bet of 100% and RSD value in the range of 3.22-4.57% The establishment of KTF with a method in accordance with the FHI has met the verification requirements, showing that the method can be used and potentially as a quality control in the manufacture of IBL leaf capsules on a production scale.
Efektivitas Metode Ekstraksi Ramah Lingkungan Terhadap Kualitas dan Efisiensi Produksi Fitofarmaka dari Jahe (Zingiber officinale): Kajian Literatur Ninjaya, Anak Agung Ngurah Gede Aditya; Dewi, Putu Mas Dyani; Dewi, Ni Putu Arya Krisna; Parta, Nyoman Adinda Triana Putri; Dewi, Ni Kadek Santi Maha
Innovative: Journal Of Social Science Research Vol. 5 No. 4 (2025): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v5i4.20313

Abstract

The increasing global demand for phytopharmaceutical products demands innovation in sustainable production processes, especially at the stage of extracting active ingredients from herbal plants such as ginger (Zingiber officinale). This study aims to evaluate the effectiveness of environmentally friendly extraction methods on the quality and efficiency of phytopharmaceutical production from ginger. The study was conducted through a systematic literature review of ten selected articles discussing green extraction methods in the period 2020 to 2025, with one exception for relevant articles outside that period. The methods studied included Ultrasound-Assisted Extraction (UAE), Microwave-Assisted Extraction (MAE), Subcritical Water Extraction (SWE), and Supercritical Fluid Extraction (SFE), considering the type of solvent, operational conditions, and main bioactive compounds such as gingerol and shogaol. The results of the analysis showed that SWE and SFE excel in terms of sustainability and purity of results, while UAE and MAE offer time and energy efficiency. The choice of solvents such as water, ethanol, and CO₂ has been shown to affect the stability of bioactive compounds and the ecological impact of the process. This study confirms that green extraction methods play an important role in ensuring the quality of the extract results while supporting environmentally responsible phytopharmaceutical production. The implications of these results encourage the adoption of sustainable approaches on an industrial scale to strengthen the competitiveness of national herbal products.
Co-Authors Dewi, Ni Putu Arya Krisna Dewi, Putu Mas Dyani Ni Kadek Warditiani Ninjaya, Anak Agung Ngurah Gede Aditya Parta, Nyoman Adinda Triana Putri Suhendi, Jessica Rianty