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All Journal Indonesian Journal of Pharmaceutical Science and Technology Innovative: Journal Of Social Science Research
Dewi, Ni Kadek Santi Maha
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Humanities Computer Science & IT Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

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Uniformity Test of Total Flavonoid Content in Antidiabetic Capsules from Ethanol Extract of Purple Sweet Potato Leaves (Ipomoea batatas L.) Suhendi, Jessica Rianty; Dewi, Ni Kadek Santi Maha; Warditiani, Ni Kadek; Arisanti, Cokorda Istri Sri; Wirasuta, I Made Agus Gelgel
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.53962

Abstract

The ethanol extract of purple sweet potato leaves (Ipomoea batatas L. or “IBL”) has antidiabetic activity, and the total flavonoid (KTF) is designated as the quality marker (Q-marker) in capsule manufacturing. This research aims to develop KTF As a Q-marker for OHT capsules from ethanol extract of IBL leaves as antidiabetic. KTF Q-marker determination involves: (1) Identification of the absorption peak of the quercetin-AlCl3 complex, (2) Method verification, and (3) Testing OHT capsule content uniformity. The Quersetin-AlCl3 complex provides a bathochromic shift in band I from 380 nm before being reacted towards 430 nm after complex formation. The method verification test resulted in a correlation coefficient of 0.998, intraday RSD of 0.76-2.00%, and interday RSD of 0.87-1.96%, and accuracy of return in the range 82.88-91.83%. The consistency test results of the capsule content of the four bets obtained a ratio of the content of 10 capsules of each bet of 100% and RSD value in the range of 3.22-4.57% The establishment of KTF with a method in accordance with the FHI has met the verification requirements, showing that the method can be used and potentially as a quality control in the manufacture of IBL leaf capsules on a production scale.
Co-Authors Dewi, Ni Putu Arya Krisna Dewi, Putu Mas Dyani Ni Kadek Warditiani Ninjaya, Anak Agung Ngurah Gede Aditya Parta, Nyoman Adinda Triana Putri Suhendi, Jessica Rianty