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Zega, Sati Agriani Zega
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Health Professions Medicine & Pharmacology Nursing

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Antibacterial Activity of the Secondary Metabolite of Fusarium LBSU Isolate from the Cat’s Whiskers Plant (Orthosiphon stamineus) Zega, Sati Agriani Zega; Halim, Rico; Ginting, Astri Natalia; Piska, Finna
Jurnal Ners Vol. 9 No. 3 (2025): JULI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.46029

Abstract

The cat's whisker plant is known to contain bioactive metabolites that have potential as therapeutic agents, while its rhizosphere is a habitat for microorganisms that produce secondary metabolites. Fusarium LBSU isolate were isolate from the rhizosphere of cat’s whiskers plant. Secondary metabolites are produced through liquid fermentation, followed by extraction using ethyl acetate. Antibacterial activity was tested using the disk diffusion method against the Escherichia coli and Staphylococcus aureus. The highest antibacterial activity obtained against Escherichia coli 23.565 mm, higher than Staphylococcus aureus which is 15.3 mm. These findings support the further development of secondary metabolites from rhizosphere isolate as an alternative source of environmentally friendly and effective antibacterial agents.
Co-Authors Ginting, Astri Natalia Halim, Rico Piska, Finna