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All Journal Edubiotik : Jurnal Pendidikan, Biologi dan Terapan
Rosalinda, Julitha D
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance

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Phytochemical profiling and anti-Staphylococcus epidermidis activity of mango leaf extract using gas chromatography-mass spectrometry Waluyo, Joko; Kuswati, Kuswati; Putri, Rizqi Wulandari; Rosalinda, Julitha D; Fatmawati, Yayuk; Habibi, Mohammad Wildan
Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Vol. 10 No. 01 (2025): Edubiotik : Jurnal Pendidikan, Biologi dan Terapan
Publisher : Biology Education Department, Universitas Insan Budi Utomo, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33503/ebio.v10i01.1177

Abstract

Staphylococcus epidermidis is increasingly recognized for its resistance to certain antibiotics, posing a significant threat due to its potential to cause infections. Plant extracts have emerged as promising alternatives owing to their diverse phytochemical composition. This study aimed to evaluate the antibacterial efficacy of the ethanolic extract of Arumanis mango leaves (Mangifera indica L. var. arumanis) against S. epidermidis and to characterize its metabolite profile using Gas Chromatography-Mass Spectrometry (GC-MS). Employing the disc diffusion method, the extract demonstrated inhibitory activity against S. epidermidis at a concentration of 2% (2 mg/ml). Subsequent GC-MS analysis identified phenols, flavonoids, and alcohols as the predominant bioactive compounds, consistent with their known antibacterial properties. These findings suggest that Arumanis mango leaf extract holds potential as a natural antibacterial agent against S. epidermidis and warrants further investigation for incorporation into natural antibacterial formulations.
Co-Authors Joko Waluyo Kuswati Kuswati Mohammad Wildan Habibi, Mohammad Wildan Putri, Rizqi Wulandari Yayuk Fatmawati, Yayuk