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All Journal SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Ilmiah Farmako Bahari
Rachmadhiani, Ana Noviana
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Antidiabetic Activity of Green Seaweed (Eucheuma spinosum) Ethanol Extract in Alloxan Induced Male White Rats (Rattus norvegicus) Rachmadhiani, Ana Noviana; Rahayuningsih, Nur; Nuryadin, Dichy
Jurnal Ilmiah Farmako Bahari Vol 16 No 2 (2025): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v16i2.42629

Abstract

Diabetes is a long-term metabolic disorder with a globally increasing prevalence, including in Indonesia. This study aims to evaluate the antidiabetic effects of the ethanol extract of Eucheuma spinosum on alloxan-induced rats in vivo. This study used an experimental design with 24 rats divided into six groups, namely the normal control group, positive control (metformin 9 mg/200 g body weight), negative control, and three treatment groups receiving Eucheuma spinosum extract at doses of 30, 60, and 120 mg/200 g body weight. The extract was obtained through the maceration method and contains active compounds such as alkaloids, flavonoids, saponins, and tannins. Blood glucose measurements were taken before and after the treatment. The yield of the extract obtained was 2.5%. The highest dose, 120 mg/200 g body weight of the rats, resulted in the most significant decrease in blood glucose levels by 39.705%. Statistical analysis using ANOVA showed a significant difference (p ≤ 0.05) between the treatment and negative control groups. The antidiabetic activity of this extract is suspected to originate from its flavonoid and saponin content, which stimulate the regeneration of pancreatic β cells and inhibit glucose absorption in the digestive tract. Ethanol extract of Eucheuma spinosum is effective in lowering blood glucose levels in diabetic rats and has the potential to be developed as a natural antidiabetic agent.
Peningkatan pengetahuan masyarakat mengenai berbagai macam dan cara pemanfaatan tanaman obat keluarga (toga) di desa Linggalaksana Wardani, Gatut Ari; Auli, Tiffani Navisha; Syahrani, Ismi; Rachmadhiani, Ana Noviana; Assidik, Rizki Abdurochman; Mujahidah, Luthfi Najdah
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 3 (2024): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i3.25379

Abstract

Abstrak Indonesia merupakan salah satu negara dengan keanekaragaman hayati yang besar sehingga kaya akan berbagai tanaman yang memiliki potensi sebagai obat. Di Desa Linggalaksana, Kecamatan Cikatomas, Kabupaten Tasikmalaya, terdapat banyak tanaman yang berpotensi sebagai tanaman obat keluarga (TOGA) diantaranya binahong dan bunga telang, namun pemahaman masyarakat Desa Linggalaksana terkait pemanfaatan tanaman obat masih rendah. Penyuluhan ini bertujuan untuk meningkatkan pengetahuan masyarakat dan mendorong budidaya Tanaman Obat Keluarga (TOGA) di Desa Linggalaksana. Melalui penyuluhan, diskusi, dan tanya jawab, pengetahuan masyarakat Desa Linggalaksana meningkat secara signifikan, dari 5,38% menjadi 61,53%. Program ini diharapkan dapat mendorong penanaman TOGA lebih luas untuk meningkatkan kesadaran akan pentingnya tanaman obat keluarga. Kata kunci: tanaman; obat; herbal; keluarga; budidaya. Abstract Indonesia is one of the countries with great biodiversity, rich in various plants with medicinal potential. In Linggalaksana Village, Cikatomas District, Tasikmalaya Regency, there are many plants with the potential to be used as family medicinal plants (TOGA), including binahong and butterfly pea flowers. However, the understanding of the Linggalaksana Village community regarding the use of medicinal plants is still low. This outreach aims to increase the community's knowledge and encourage the cultivation of Family Medicinal Plants (TOGA) in Linggalaksana Village. Through outreach, discussions, and question-and-answer sessions, the knowledge of the Linggalaksana Village community increased significantly, from 5.38% to 61.53%. This program is expected to encourage wider TOGA planting to raise awareness of the importance of family medicinal plants. Keywords: plants; medicine; herbs; family; cultivation.
Co-Authors Assidik, Rizki Abdurochman Auli, Tiffani Navisha Gatut Ari Wardani Mujahidah, Luthfi Najdah Nur Rahayuningsih, Nur Nuryadin, Dichy Syahrani, Ismi