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All Journal Padjadjaran Journal of Dentistry Interdental Jurnal Kedokteran Gigi (IJKG)
Sanjaya, Devita
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Effect Of 8% Ethyl Acetate Fractionated Coriander Seed (Coriandrum sativum) Extract Gel on The Number of Neutrophils and Fibroblasts in The Healing Process of Gingivitis (in vivo Study on Wistar Rats) Sanjaya, Devita; Nur, Asikin; Kuswandari, Sri
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.9724

Abstract

Introduction: Gingivitis is inflammation of the gingiva and the initial stage of periodontal disease, which, if not treated, will become periodontitis. Coriander seeds (Coriandrum sativum) have anti-bacterial and anti-inflammatory properties. This study aimed to determine the effect of 8% ethyl acetate fractionated coriander seed extract gel on the number of neutrophils and fibroblasts in the healing process of gingivitis (in vivo) in Wistar rats. Material and Method: Thirty-six rats were divided into 3 groups: the 8% ethyl acetate fractionated coriander seed extract gel group, the chlorhexidine gel group, and the placebo gel group. Gingivitis was induced by tying a silk ligation to the subgingival area of ​​the lower incisor for 7 days. 0.05 ml of gel was applied twice a day in the gingivitis area. On days 1, 3, 5, and 7, three rats from each group were decapitated, histological preparations were made with HE staining, and the number of neutrophils and fibroblasts was counted using an Optilab microscope with 400x magnification. Healing assessment was measured based on the decrease in the number of neutrophils or the increase in the number of fibroblasts compared to the number of neutrophils or fibroblasts on the initial observation day. Results and Discussions: A significant difference in neutrophil counts was found in the 8% ethyl acetate fractionated coriander seed extract gel group (45.43%) and the placebo gel group (51.67%) on days 3. A significant difference was also found in the number of fibroblast in the 8% ethyl acetate fractionated coriander seed extract gel group (5410%) and the placebo gel group (4470%) on days 5, and between the 8% ethyl acetate fractionated coriander seed extract gel group (8463.33%) and the placebo gel group (7953.33%) on days 7. Conclusion: This research concludes that 8% ethyl acetate fractionated coriander seed extract gel can reduce the number of neutrophils and increase the number of fibroblasts in the gingivitis healing process.
Management of anterior crossbite in mixed dentition using sloped composite resin: a case report Sanjaya, Devita; Kuswandari, Sri
Padjadjaran Journal of Dentistry Vol 38, No 1 (2026): March 2026
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol38no1.62790

Abstract

Introduction: Dental-type anterior crossbite is a malocclusion involving an individual tooth, in which the maxillary incisor is positioned lingual to the mandibular incisor without skeletal discrepancy. Its most common aetiology is persistence of a primary tooth, which may disrupt the eruption path and lead to palatal eruption of the permanent successor. Sloped composite resin is a simple and effective method for correcting an anterior crossbite. In the cases presented, the dental crossbite was corrected by applying a 3-4 mm bonded resin-composite inclined plane to the incisal edge of the mandibular incisors at an angle of approximately 45° to the long axis of the tooth. This case report aimed to describe the management of dental-type anterior crossbite involving individual teeth using sloped composite resin in children during the mixed dentition period. Case report: Three cases of anterior crossbite were managed in three paediatric patients. The first case involved an 8-year-old boy with a crossbite affecting teeth 11 and 21. The second case involved an 8-year-old boy with a crossbite of tooth 21, and the third case involved a 7-year-old girl with a crossbite affecting teeth 11 and 21. All patients had good oral hygiene and no deleterious oral habits. The available arch space exceeded the mesiodistal width of the affected incisors. Sloped composite resin was applied to the antagonist mandibular incisors, either directly or indirectly, at an angle of approximately 45° to the long axis of the tooth. On average, the crossbites were corrected within two weeks. Conclusion: This case report demonstrates that direct and indirect sloped composite resin applications can provide rapid and consistent correction of dental-type anterior crossbite during the mixed dentition period. The technique was effective, minimally complex and clinically practical, with an average correction time of two weeks.
Co-Authors Asikin Nur Sri Kuswandari, Sri