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All Journal Jurnal Respirasi (JR) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Pradnyandari, Anak Agung Sagung Putri
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Clinical and Radiological Characteristics of Pneumonia in COVID-19 Patients at First Admission of Dr. Soetomo General Academic Hospital, Surabaya, in June-August 2021 Pradnyandari, Anak Agung Sagung Putri; Hasan, Helmia; Setiawati, Rosy; Effendi, Wiwin Is
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.115-121

Abstract

Highlights: This was the first study that described the radiological features of pneumonia in COVID-19 patients at first admission to Dr. Soetomo General Academic Hospital, Surabaya, during the Delta wave. This study presented the gastrointestinal symptoms of COVID-19 patients with pneumonia.   Abstract Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gave rise to the coronavirus disease (COVID-19) pandemic. Pneumonia in COVID-19 can cause acute respiratory distress syndrome (ARDS), which could lead to damage to end organs. This study aimed to describe the clinical and radiological profile of pneumonia in COVID-19 patients at first admission to the emergency department of Dr. Soetomo General Academic Hospital, Surabaya, in June-August 2021. Methods: This was a single-center, descriptive study of COVID-19 patients with pneumonia (n=193) at their first admission to the emergency department of Dr. Soetomo General Academic Hospital, Surabaya, from June to August 2021. The demographic data, pre-existing comorbidities, clinical signs and symptoms, and radiological findings were collected from the electronic medical record and analysed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26. Results: Out of all the COVID-19 patients included in the study (n=193), most of them were 18-64 years old (86.0%), and the majority were males (50.8%). Of 193 patients, 51.3% had pre-existing comorbidities. Most patients (95.9%) experienced pulmonary symptoms, with shortness of breath being the most common. On chest radiograph, 60.1% patients showed consolidation with central and peripheral predominance (60.6%) and bilateral lung involvement (91.2%). Conclusion: This study presented a description of the clinical and radiological findings in COVID-19 patients with pneumonia. Most of which showed extensive lesions on chest radiograph along with dyspnea, which may suggest that most patients were suffering from late-stage and severe COVID-19 with pneumonia. To confirm this suggestion, further research is needed.
Disseminated Tuberculosis in An Immunocompetent Patient Presenting with Ptosis and Diplopia: A Case Report Zahra, Nadhifa Az; Pradnyandari, Anak Agung Sagung Putri; Kusmiati, Tutik; Widjaja, Stella Agatha
Jurnal Respirasi Vol. 11 No. 3 (2025): September 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.3.2025.269-275

Abstract

Introduction: Tuberculosis (TB) remains a global health burden to this day, with pulmonary TB (PTB) being one of its most common types. A lapse in the host immune response may lead to the dissemination of TB infection, causing extrapulmonary TB (EPTB) that is more difficult to manage, as it frequently shows atypical complaints. However, its manifestations among immunocompetent patients are rarely well-investigated. Case: A 28-year-old human immunodeficiency virus (HIV)-negative woman presented with a history of chronic progressive bilateral headache, followed by diplopia and ptosis of her left eyelid. She also had classical TB symptoms 3 months prior. She had a history of household tuberculous contact for years, but she was never tested for TB nor given an anti-TB treatment (ATT). Chest X-ray revealed cavities and pleural thickening in the apex of the left lung. Contrast-enhanced magnetic resonance imaging (MRI) of the brain showed multiple intracranial tuberculomas and meningeal enhancement in most brain areas. GeneXpert tests from both sputum and cerebrospinal fluid (CSF) suggested TB infections. She was later diagnosed with simultaneous tuberculous meningoencephalitis (TBME) and PTB. After a 17-day course of oral ATT, streptomycin injection, and intravenous corticosteroid, she was discharged with improved clinical conditions and scheduled for outpatient follow-up until she completed 12 months of ATT. Conclusion: In immunocompetent patients, disseminated TB is an uncommon occurrence and is frequently characterized by atypical symptoms. Findings from this case emphasize that comprehensive assessment and timely therapeutic intervention are critical for minimizing morbidity and mortality of TB infection.
Co-Authors Effendi, Wiwin Is Hasan, Helmia Kusmiati, Tutik Setiawati, Rosy Widjaja, Stella Agatha Zahra, Nadhifa Az