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All Journal Jurnal Respirasi (JR) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Effendi, Wiwin Is
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Appendicular Tuberculosis as Manifestation of Gastrointestinal Tuberculosis: A Case Report Yuliza Yuliza; Alfian Nur Rosyid; Wiwin Is Effendi; Prastuti Asta Wulaningrum; Herley Windo Setiawan
Jurnal Respirasi Vol. 7 No. 3 (2021): September 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.745 KB) | DOI: 10.20473/jr.v7-I.3.2021.122-126

Abstract

Introduction: Gastrointestinal tuberculosis (GI TB) is quite rare with 3% incidence of all extrapulmonary involvement. Appendicular TB may occur in 0.1 - 3% of cases. Diagnosis is often difficult because the patient usually complains about chronic abdominal pain and fever. A definite diagnosis is based on histopathological examination of resected specimens from the appendectomy procedure.Case: We present a 37-year-old male patient admitted to the hospital with chronic abdominal pain, fever, nausea, and loss of body weight. The patient never had a persistent cough, hemoptysis, or night sweating. Physical examination showed pain and muscular rigidity in the right iliac area during palpation with Blumberg's sign and Rovsing's sign positive. Abdomen ultrasound imaging showed an appendicular abscess. The patient underwent appendectomy afterwards with histopathology result showing TB. The patient was treated with first category anti-tuberculosis drugs (ATD).Discussion: Diagnosis of appendicular TB is difficult due to unspecific clinical presentations. Appendicular TB patients often complain of signs and symptoms which are similar to acute appendicitis. These conditions can delay ATD treatment because the definitive diagnosis could be made after histopathological examination.Summary: Appendicular TB is a rare case of extrapulmonary TB. It can present as acute appendicitis. The definitive diagnosis is based on the histopathological examination. It is recommended to check the appendicectomy specimens histopathologically to exclude TB or other diseases. 
The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital Arifandi, Yoga Akbar; Rosyid, Alfian Nur; Indiastuti, Danti Nur; Effendi, Wiwin Is
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 1 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I12025.63-69

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Highlights: The administration of different dosages of vitamin C significantly yields different outcomes in preventing the progression of disease severity. Most patients with mild and moderate coronavirus disease (COVID-19) did not demonstrate an escalation in disease severity.   Abstract Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties.  This study aimed to explain the impact of three distinct vitamin C supplementation dosages in preventing disease severity progression among mild and moderate COVID-19 patients. Methods: This retrospective study used secondary data from 100 medical records (n=100). The subjects were classified into three categories based on the vitamin C dosage. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26.0 for Windows. Results: Most of mild and moderate COVID-19 patients (78%) did not experience increased disease severity. Vitamin C supplementation significantly demonstrated a different outcome in preventing disease severity progression among the three groups (p=0.018). However, it did not significantly show any difference in reducing the duration of hospital stay (p=0.680). Conclusion: The impact of vitamin C supplementation on COVID-19 severity appeared to vary depending on the dosage administered. However, it did not affect the duration of the hospital stay.
Clinical and Radiological Characteristics of Pneumonia in COVID-19 Patients at First Admission of Dr. Soetomo General Academic Hospital, Surabaya, in June-August 2021 Pradnyandari, Anak Agung Sagung Putri; Hasan, Helmia; Setiawati, Rosy; Effendi, Wiwin Is
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.115-121

Abstract

Highlights: This was the first study that described the radiological features of pneumonia in COVID-19 patients at first admission to Dr. Soetomo General Academic Hospital, Surabaya, during the Delta wave. This study presented the gastrointestinal symptoms of COVID-19 patients with pneumonia.   Abstract Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gave rise to the coronavirus disease (COVID-19) pandemic. Pneumonia in COVID-19 can cause acute respiratory distress syndrome (ARDS), which could lead to damage to end organs. This study aimed to describe the clinical and radiological profile of pneumonia in COVID-19 patients at first admission to the emergency department of Dr. Soetomo General Academic Hospital, Surabaya, in June-August 2021. Methods: This was a single-center, descriptive study of COVID-19 patients with pneumonia (n=193) at their first admission to the emergency department of Dr. Soetomo General Academic Hospital, Surabaya, from June to August 2021. The demographic data, pre-existing comorbidities, clinical signs and symptoms, and radiological findings were collected from the electronic medical record and analysed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26. Results: Out of all the COVID-19 patients included in the study (n=193), most of them were 18-64 years old (86.0%), and the majority were males (50.8%). Of 193 patients, 51.3% had pre-existing comorbidities. Most patients (95.9%) experienced pulmonary symptoms, with shortness of breath being the most common. On chest radiograph, 60.1% patients showed consolidation with central and peripheral predominance (60.6%) and bilateral lung involvement (91.2%). Conclusion: This study presented a description of the clinical and radiological findings in COVID-19 patients with pneumonia. Most of which showed extensive lesions on chest radiograph along with dyspnea, which may suggest that most patients were suffering from late-stage and severe COVID-19 with pneumonia. To confirm this suggestion, further research is needed.
Co-Authors Arifandi, Yoga Akbar Hasan, Helmia Herley Windo Setiawan Indiastuti, Danti Nur Pradnyandari, Anak Agung Sagung Putri Prastuti Asta Wulaningrum Rosyid, Alfian Nur Setiawati, Rosy Yuliza Yuliza