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Mustika Sari, Rahayu
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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FORMULASI DAN UJI SIFAT FISIK LIP BALM ESKTRAK ETANOL BUAH STRAWBERRY (Fragraria Sp) Mustika Sari, Rahayu
Journal of Pharmacy Tiara Bunda Vol. 2 No. 1 (2022): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i1.66

Abstract

Lip balm is a preparation that is applied to the lips to function as a moisturizer by forming a layer of oil that does not mix on the surface of the lips. Strawberry (Fragraria) functions as an antioxidant and anti-inflammatory so that the strawberry fruit extract can be used as a moisturizer and will be maximized when used in the form of cosmetic products. The aim was to determine whether the ethanol extract of strawberry fruit (Fragraria) can be used in lip balm preparations and the difference in the ethanol extract concentration of strawberry fruit (fragraria) could affect the physical properties of lip balm preparations and determine the concentration of what lip balm preparations preferred by respondents. Strawberry fruit is obtained in the mountainous area of Tegal district. The extraction method used in this research is the maceration method with a concentration of 5%, 10% and 15%. The evaluation of lip balm preparations includes organoleptic test, pH test, irritation test, preference test, homogeneity test, smear test, melting point test. The results showed that the lip balm preparation of strawberry fruit extract (Fragraria) had no effect on the physical properties of the lip balm preparation. Formulas 1, 2 and 3 produce good physical properties, which include organoleptic tests, homogeneity tests, pH tests, melting point tests, irritation tests, and spreadability tests. Based on the preference test which includes color, aroma and moisture, formula 1 is the most preferred formula with a preference for color and aroma as much as 90% with the humidity level of 80%
Formulasi dan Uji Stabilitas Fisik Sediaan Salep Dari Fraksi Daun Kemangi (Ocimun sanctum L) Mustika Sari, Rahayu
Journal of Pharmacy Tiara Bunda Vol. 3 No. 2 (2023): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v1i2.86

Abstract

This basil plant (Ocimum Sanctum.Lin.) contains: essential oils, alkaloids, eugenol, rosmarinic acid, saponins, flavonoids, tannins and phenols. This study aims to determine the preparation of ointment from the basil leaf fraction that meets the requirements of the physical quality of the preparation and to determine the effect of variations in the ointment base from basil leaves by testing the physical stability of the preparation. This research was conducted using the one-way Anova statistical test followed by the Tukey test and the data were analyzed using Kurskal Wallis and Man Withney then tested for the physical properties and stability of the ointment which included organoleptic tests, homogeneity tests, pH tests, viscosity tests, dispersibility tests, and adhesion test. The results showed that basil leaf extract could be formulated into ointment preparations from the basil leaf fraction (Ocimum Sanctum L) into ointment preparations with various base variations that met the physical quality requirements of the preparation and in this study there was an effect of variations in the ointment base from the basil leaf fraction ( hydrocarbon base, absorption base and water soluble base) based on the physical stability test of the ointment preparation. So it can be concluded that the Basil leaf extracts and fractions can be formulated into ointment preparations (Ocimum Sanctum L) but do not meet the physical quality requirements of the preparation and have the effect of base variations on the ointment preparation
ANALISA DRUG RELATED PROBLEM PADA ENDOMETRIOSIS DI PUSKESMAS DUREN SERIBU PERIODE 1 JANUARI - 30 JUNI 2025 Mustika Sari, Rahayu; Ambarsari, Niati
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.276

Abstract

This study analyzed the incidence of drug-related problems, including adverse events and medical errors, and possible associated risk factors, in patients with endometriosis who used combined oral contraceptives (COCs) and progestins. Reports were collected between January 1, 2024, and June 30, 2025, regarding endometriosis patients in the Medical Record System at the Duren Seribu Community Health Center, Depok City. A disproportionate analysis was performed using the Gamma–Poisson Shrinker model to detect overreported drug–event pairs. Logistic regression analysis was used to explore potential risk factors. There were 23 reports regarding long-term hormonal treatment and 45 reports regarding other medications used for endometriosis. Long-term hormonal treatment included: 15 reports (22.0%) of combined oral contraceptives (COCs), 10 reports (14.7%) of oral progestins, 8 reports (11.76%) of injectable (depot) progestins, 23 reports (33.82%) of progestin-releasing IUDs, and 12 reports (17.64%) of progestin-only implants. Both combined oral contraceptives (COCs) and progestin-only products are relatively safe for patients with endometriosis. Combination therapy (polytherapy) has been negatively associated with several medical errors in COC users, while patients aged ≥30 years have had more pulmonary embolism cases but fewer reported product-related problems.
Co-Authors Ambarsari, Niati